L1CAM: Cell adhesion and more
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L1CAM: Cell adhesion and more. / Samatov, Timur R; Wicklein, Daniel; Tonevitsky, Alexander G.
In: PROG HISTOCHEM CYTO, Vol. 51, No. 2, 08.2016, p. 25-32.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
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TY - JOUR
T1 - L1CAM: Cell adhesion and more
AU - Samatov, Timur R
AU - Wicklein, Daniel
AU - Tonevitsky, Alexander G
N1 - Copyright © 2016 Elsevier GmbH. All rights reserved.
PY - 2016/8
Y1 - 2016/8
N2 - L1CAM is a cell adhesion molecule of the immunoglobulin superfamily which was originally discovered as a major player in the development of the nervous system. L1CAM was demonstrated to have prognostic value in different cancers and to be a promising target for anti-cancer therapy. Here we overview the present data on L1CAM structure and function, regulation of its expression, role in cancer and therapeutic potential.
AB - L1CAM is a cell adhesion molecule of the immunoglobulin superfamily which was originally discovered as a major player in the development of the nervous system. L1CAM was demonstrated to have prognostic value in different cancers and to be a promising target for anti-cancer therapy. Here we overview the present data on L1CAM structure and function, regulation of its expression, role in cancer and therapeutic potential.
KW - Journal Article
KW - Review
U2 - 10.1016/j.proghi.2016.05.001
DO - 10.1016/j.proghi.2016.05.001
M3 - SCORING: Journal article
C2 - 27267927
VL - 51
SP - 25
EP - 32
JO - PROG HISTOCHEM CYTO
JF - PROG HISTOCHEM CYTO
SN - 0079-6336
IS - 2
ER -