Ischemia-reperfusion-induced unmeasured anion generation and glycocalyx shedding: sevoflurane versus propofol anesthesia.
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Ischemia-reperfusion-induced unmeasured anion generation and glycocalyx shedding: sevoflurane versus propofol anesthesia. / Annecke, Thorsten; Rehm, Markus; Bruegger, Dirk; Kubitz, Jens; Kemming, Gregor I; Stoekelhuber, Mechthild; Becker, Bernhard F; Conzen, Peter F.
In: J INVEST SURG, Vol. 25, No. 3, 3, 2012, p. 162-168.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
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TY - JOUR
T1 - Ischemia-reperfusion-induced unmeasured anion generation and glycocalyx shedding: sevoflurane versus propofol anesthesia.
AU - Annecke, Thorsten
AU - Rehm, Markus
AU - Bruegger, Dirk
AU - Kubitz, Jens
AU - Kemming, Gregor I
AU - Stoekelhuber, Mechthild
AU - Becker, Bernhard F
AU - Conzen, Peter F
PY - 2012
Y1 - 2012
N2 - Vascular leakage after ischemia-reperfusion (IR) is largely attributed to the destruction of the endothelial barrier and its associated negatively charged glycocalyx. In vitro, sevoflurane attenuates these changes. Therefore, we compared sevoflurane with propofol with regard to the protection of the glycocalyx and the release of negatively charged substances in vivo.
AB - Vascular leakage after ischemia-reperfusion (IR) is largely attributed to the destruction of the endothelial barrier and its associated negatively charged glycocalyx. In vitro, sevoflurane attenuates these changes. Therefore, we compared sevoflurane with propofol with regard to the protection of the glycocalyx and the release of negatively charged substances in vivo.
KW - Animals
KW - Male
KW - Female
KW - Disease Models, Animal
KW - Sus scrofa
KW - Acid-Base Equilibrium/drug effects
KW - Anesthetics/pharmacology
KW - Capillary Permeability/drug effects
KW - Endothelium, Vascular/drug effects/injuries
KW - Glycocalyx/drug effects/metabolism/pathology
KW - Heparitin Sulfate/metabolism
KW - Methyl Ethers/pharmacology
KW - Propofol/pharmacology
KW - Reperfusion Injury/metabolism/pathology/prevention & control
KW - Animals
KW - Male
KW - Female
KW - Disease Models, Animal
KW - Sus scrofa
KW - Acid-Base Equilibrium/drug effects
KW - Anesthetics/pharmacology
KW - Capillary Permeability/drug effects
KW - Endothelium, Vascular/drug effects/injuries
KW - Glycocalyx/drug effects/metabolism/pathology
KW - Heparitin Sulfate/metabolism
KW - Methyl Ethers/pharmacology
KW - Propofol/pharmacology
KW - Reperfusion Injury/metabolism/pathology/prevention & control
M3 - SCORING: Journal article
VL - 25
SP - 162
EP - 168
JO - J INVEST SURG
JF - J INVEST SURG
SN - 0894-1939
IS - 3
M1 - 3
ER -