Research ExplorerPublicationsIs there a 'gut-brain-skin axis'?

Is there a 'gut-brain-skin axis'?

Standard

Is there a 'gut-brain-skin axis'? / Arck, Petra; Handjiski, Bori; Hagen, Evelin; Pincus, Maike; Bruenahl, Christian; Bienenstock, John; Paus, Ralf.

In: EXP DERMATOL, Vol. 19, No. 5, 5, 2010, p. 401-405.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Arck, P, Handjiski, B, Hagen, E, Pincus, M, Bruenahl, C, Bienenstock, J & Paus, R 2010, 'Is there a 'gut-brain-skin axis'?', EXP DERMATOL, vol. 19, no. 5, 5, pp. 401-405. https://doi.org/10.1111/j.1600-0625.2009.01060.x

APA

Arck, P., Handjiski, B., Hagen, E., Pincus, M., Bruenahl, C., Bienenstock, J., & Paus, R. (2010). Is there a 'gut-brain-skin axis'? EXP DERMATOL, 19(5), 401-405. [5]. https://doi.org/10.1111/j.1600-0625.2009.01060.x

Vancouver

Arck P, Handjiski B, Hagen E, Pincus M, Bruenahl C, Bienenstock J et al. Is there a 'gut-brain-skin axis'? EXP DERMATOL. 2010;19(5):401-405. 5. https://doi.org/10.1111/j.1600-0625.2009.01060.x

Bibtex

@article{76fdd43271b7410fb1d2780997e943c1,
title = "Is there a 'gut-brain-skin axis'?",
abstract = "Emerging evidence arising from interdisciplinary research supports the occurrence of communication axes between organs, such as the brain-gut or brain-skin axis. The latter is employed in response to stress challenge, along which neurogenic skin inflammation and hair growth inhibition is mediated. We now show that ingestion of a Lactobacillus strain in mice dampens stress-induced neurogenic skin inflammation and the hair growth inhibition. In conclusion, we are introducing a hypothesis, encouraged by our pilot observations and resting upon published prior evidence from the literature, which amalgamates previously proposed partial concepts into a new, unifying model, i.e. the gut-brain-skin axis. This concept suggests that modulation of the microbiome by deployment of probiotics can not only greatly reduce stress-induced neurogenic skin inflammation but even affect a very complex cutaneous phenomenon of (mini-) organ transformation, i.e. hair follicle cycling. These observations raise the intriguing prospect that feeding of just the right kind of bacteria can exert profound beneficial effects on skin homoeostasis, skin inflammation, hair growth and peripheral tissue responses to perceived stress.",
author = "Petra Arck and Bori Handjiski and Evelin Hagen and Maike Pincus and Christian Bruenahl and John Bienenstock and Ralf Paus",
year = "2010",
doi = "10.1111/j.1600-0625.2009.01060.x",
language = "Deutsch",
volume = "19",
pages = "401--405",
journal = "EXP DERMATOL",
issn = "0906-6705",
publisher = "Wiley-Blackwell",
number = "5",

}

RIS

TY - JOUR

T1 - Is there a 'gut-brain-skin axis'?

AU - Arck, Petra

AU - Handjiski, Bori

AU - Hagen, Evelin

AU - Pincus, Maike

AU - Bruenahl, Christian

AU - Bienenstock, John

AU - Paus, Ralf

PY - 2010

Y1 - 2010

N2 - Emerging evidence arising from interdisciplinary research supports the occurrence of communication axes between organs, such as the brain-gut or brain-skin axis. The latter is employed in response to stress challenge, along which neurogenic skin inflammation and hair growth inhibition is mediated. We now show that ingestion of a Lactobacillus strain in mice dampens stress-induced neurogenic skin inflammation and the hair growth inhibition. In conclusion, we are introducing a hypothesis, encouraged by our pilot observations and resting upon published prior evidence from the literature, which amalgamates previously proposed partial concepts into a new, unifying model, i.e. the gut-brain-skin axis. This concept suggests that modulation of the microbiome by deployment of probiotics can not only greatly reduce stress-induced neurogenic skin inflammation but even affect a very complex cutaneous phenomenon of (mini-) organ transformation, i.e. hair follicle cycling. These observations raise the intriguing prospect that feeding of just the right kind of bacteria can exert profound beneficial effects on skin homoeostasis, skin inflammation, hair growth and peripheral tissue responses to perceived stress.

AB - Emerging evidence arising from interdisciplinary research supports the occurrence of communication axes between organs, such as the brain-gut or brain-skin axis. The latter is employed in response to stress challenge, along which neurogenic skin inflammation and hair growth inhibition is mediated. We now show that ingestion of a Lactobacillus strain in mice dampens stress-induced neurogenic skin inflammation and the hair growth inhibition. In conclusion, we are introducing a hypothesis, encouraged by our pilot observations and resting upon published prior evidence from the literature, which amalgamates previously proposed partial concepts into a new, unifying model, i.e. the gut-brain-skin axis. This concept suggests that modulation of the microbiome by deployment of probiotics can not only greatly reduce stress-induced neurogenic skin inflammation but even affect a very complex cutaneous phenomenon of (mini-) organ transformation, i.e. hair follicle cycling. These observations raise the intriguing prospect that feeding of just the right kind of bacteria can exert profound beneficial effects on skin homoeostasis, skin inflammation, hair growth and peripheral tissue responses to perceived stress.

U2 - 10.1111/j.1600-0625.2009.01060.x

DO - 10.1111/j.1600-0625.2009.01060.x

M3 - SCORING: Zeitschriftenaufsatz

VL - 19

SP - 401

EP - 405

JO - EXP DERMATOL

JF - EXP DERMATOL

SN - 0906-6705

IS - 5

M1 - 5

ER -