Intraoperative hypotension: Pathophysiology, clinical relevance, and therapeutic approaches

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Intraoperative hypotension: Pathophysiology, clinical relevance, and therapeutic approaches. / Kouz, Karim; Hoppe, Phillip; Briesenick, Luisa; Saugel, Bernd.

In: INDIAN J ANAESTH, Vol. 64, No. 2, 02.2020, p. 90-96.

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@article{eb79219edcd84ee6bff180534a9aa303,
title = "Intraoperative hypotension: Pathophysiology, clinical relevance, and therapeutic approaches",
abstract = "Intraoperative hypotension (IOH) i.e., low arterial blood pressure (AP) during surgery is common in patients having non-cardiac surgery under general anaesthesia. It has a multifactorial aetiology, and is associated with major postoperative complications including acute kidney injury, myocardial injury and death. Therefore, IOH may be a modifiable risk factor for postoperative complications. However, there is no uniform definition for IOH. IOH not only occurs during surgery but also after the induction of general anaesthesia before surgical incision. However, the optimal therapeutic approach to IOH remains elusive. There is evidence from one small randomised controlled trial that individualising AP targets may reduce the risk of postoperative organ dysfunction compared with standard care. More research is needed to define individual AP harm thresholds, to develop therapeutic strategies to treat and avoid IOH, and to integrate new technologies for continuous AP monitoring.",
author = "Karim Kouz and Phillip Hoppe and Luisa Briesenick and Bernd Saugel",
note = "Copyright: {\textcopyright} 2020 Indian Journal of Anaesthesia.",
year = "2020",
month = feb,
doi = "10.4103/ija.IJA_939_19",
language = "English",
volume = "64",
pages = "90--96",
journal = "INDIAN J ANAESTH",
issn = "0019-5049",
publisher = "Medknow Publications and Media Pvt. Ltd",
number = "2",

}

RIS

TY - JOUR

T1 - Intraoperative hypotension: Pathophysiology, clinical relevance, and therapeutic approaches

AU - Kouz, Karim

AU - Hoppe, Phillip

AU - Briesenick, Luisa

AU - Saugel, Bernd

N1 - Copyright: © 2020 Indian Journal of Anaesthesia.

PY - 2020/2

Y1 - 2020/2

N2 - Intraoperative hypotension (IOH) i.e., low arterial blood pressure (AP) during surgery is common in patients having non-cardiac surgery under general anaesthesia. It has a multifactorial aetiology, and is associated with major postoperative complications including acute kidney injury, myocardial injury and death. Therefore, IOH may be a modifiable risk factor for postoperative complications. However, there is no uniform definition for IOH. IOH not only occurs during surgery but also after the induction of general anaesthesia before surgical incision. However, the optimal therapeutic approach to IOH remains elusive. There is evidence from one small randomised controlled trial that individualising AP targets may reduce the risk of postoperative organ dysfunction compared with standard care. More research is needed to define individual AP harm thresholds, to develop therapeutic strategies to treat and avoid IOH, and to integrate new technologies for continuous AP monitoring.

AB - Intraoperative hypotension (IOH) i.e., low arterial blood pressure (AP) during surgery is common in patients having non-cardiac surgery under general anaesthesia. It has a multifactorial aetiology, and is associated with major postoperative complications including acute kidney injury, myocardial injury and death. Therefore, IOH may be a modifiable risk factor for postoperative complications. However, there is no uniform definition for IOH. IOH not only occurs during surgery but also after the induction of general anaesthesia before surgical incision. However, the optimal therapeutic approach to IOH remains elusive. There is evidence from one small randomised controlled trial that individualising AP targets may reduce the risk of postoperative organ dysfunction compared with standard care. More research is needed to define individual AP harm thresholds, to develop therapeutic strategies to treat and avoid IOH, and to integrate new technologies for continuous AP monitoring.

U2 - 10.4103/ija.IJA_939_19

DO - 10.4103/ija.IJA_939_19

M3 - SCORING: Review article

C2 - 32139925

VL - 64

SP - 90

EP - 96

JO - INDIAN J ANAESTH

JF - INDIAN J ANAESTH

SN - 0019-5049

IS - 2

ER -