Intraoperative hypotension: Pathophysiology, clinical relevance, and therapeutic approaches
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Intraoperative hypotension: Pathophysiology, clinical relevance, and therapeutic approaches. / Kouz, Karim; Hoppe, Phillip; Briesenick, Luisa; Saugel, Bernd.
In: INDIAN J ANAESTH, Vol. 64, No. 2, 02.2020, p. 90-96.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
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TY - JOUR
T1 - Intraoperative hypotension: Pathophysiology, clinical relevance, and therapeutic approaches
AU - Kouz, Karim
AU - Hoppe, Phillip
AU - Briesenick, Luisa
AU - Saugel, Bernd
N1 - Copyright: © 2020 Indian Journal of Anaesthesia.
PY - 2020/2
Y1 - 2020/2
N2 - Intraoperative hypotension (IOH) i.e., low arterial blood pressure (AP) during surgery is common in patients having non-cardiac surgery under general anaesthesia. It has a multifactorial aetiology, and is associated with major postoperative complications including acute kidney injury, myocardial injury and death. Therefore, IOH may be a modifiable risk factor for postoperative complications. However, there is no uniform definition for IOH. IOH not only occurs during surgery but also after the induction of general anaesthesia before surgical incision. However, the optimal therapeutic approach to IOH remains elusive. There is evidence from one small randomised controlled trial that individualising AP targets may reduce the risk of postoperative organ dysfunction compared with standard care. More research is needed to define individual AP harm thresholds, to develop therapeutic strategies to treat and avoid IOH, and to integrate new technologies for continuous AP monitoring.
AB - Intraoperative hypotension (IOH) i.e., low arterial blood pressure (AP) during surgery is common in patients having non-cardiac surgery under general anaesthesia. It has a multifactorial aetiology, and is associated with major postoperative complications including acute kidney injury, myocardial injury and death. Therefore, IOH may be a modifiable risk factor for postoperative complications. However, there is no uniform definition for IOH. IOH not only occurs during surgery but also after the induction of general anaesthesia before surgical incision. However, the optimal therapeutic approach to IOH remains elusive. There is evidence from one small randomised controlled trial that individualising AP targets may reduce the risk of postoperative organ dysfunction compared with standard care. More research is needed to define individual AP harm thresholds, to develop therapeutic strategies to treat and avoid IOH, and to integrate new technologies for continuous AP monitoring.
U2 - 10.4103/ija.IJA_939_19
DO - 10.4103/ija.IJA_939_19
M3 - SCORING: Review article
C2 - 32139925
VL - 64
SP - 90
EP - 96
JO - INDIAN J ANAESTH
JF - INDIAN J ANAESTH
SN - 0019-5049
IS - 2
ER -