Intracranial hemorrhage, outcome, and mortality after intra-arterial therapy for acute ischemic stroke in patients under oral anticoagulants.
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Intracranial hemorrhage, outcome, and mortality after intra-arterial therapy for acute ischemic stroke in patients under oral anticoagulants. / Marchis, De; Marco, Gian; Jung, Simon; Colucci, Giuseppe; Meier, Niklaus; Fischer, Urs; Weck, Anja; Mono, Marie-Luise; Galimanis, Aekaterini; Mattle, Heinrich P; Schroth, Gerhard; Gralla, Jan; Brekenfeld, Caspar; Brekenfeld, Caspar.
In: STROKE, Vol. 42, No. 11, 11, 2011, p. 3061-3066.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
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TY - JOUR
T1 - Intracranial hemorrhage, outcome, and mortality after intra-arterial therapy for acute ischemic stroke in patients under oral anticoagulants.
AU - Marchis, De
AU - Marco, Gian
AU - Jung, Simon
AU - Colucci, Giuseppe
AU - Meier, Niklaus
AU - Fischer, Urs
AU - Weck, Anja
AU - Mono, Marie-Luise
AU - Galimanis, Aekaterini
AU - Mattle, Heinrich P
AU - Schroth, Gerhard
AU - Gralla, Jan
AU - Brekenfeld, Caspar
AU - Brekenfeld, Caspar
PY - 2011
Y1 - 2011
N2 - Use of intravenous tissue-type plasminogen activator (IV tPA) for acute ischemic stroke is restricted to patients with an international normalized ratio (INR) less than 1.7. However, a recent study showed increased risk of symptomatic intracranial hemorrhage after IV tPA use in patients with oral anticoagulants (OAC) even with an INR less than 1.7. The present study assessed the risk of symptomatic intracranial hemorrhage, clinical outcome, and mortality after intra-arterial therapy (IAT) in patients with and without previous use of OAC.
AB - Use of intravenous tissue-type plasminogen activator (IV tPA) for acute ischemic stroke is restricted to patients with an international normalized ratio (INR) less than 1.7. However, a recent study showed increased risk of symptomatic intracranial hemorrhage after IV tPA use in patients with oral anticoagulants (OAC) even with an INR less than 1.7. The present study assessed the risk of symptomatic intracranial hemorrhage, clinical outcome, and mortality after intra-arterial therapy (IAT) in patients with and without previous use of OAC.
M3 - SCORING: Journal article
VL - 42
SP - 3061
EP - 3066
JO - STROKE
JF - STROKE
SN - 0039-2499
IS - 11
M1 - 11
ER -