Intestinal Kaposi's sarcoma may mimic gastrointestinal stromal tumor in HIV infection.
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Intestinal Kaposi's sarcoma may mimic gastrointestinal stromal tumor in HIV infection. / Zoufaly, Alexander; Schmiedel, Stefan; Lohse, Ansgar W.; van Lunzen, Jan.
In: WORLD J GASTROENTERO, Vol. 13, No. 33, 33, 2007, p. 4514-4516.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
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TY - JOUR
T1 - Intestinal Kaposi's sarcoma may mimic gastrointestinal stromal tumor in HIV infection.
AU - Zoufaly, Alexander
AU - Schmiedel, Stefan
AU - Lohse, Ansgar W.
AU - van Lunzen, Jan
PY - 2007
Y1 - 2007
N2 - Diffuse intestinal Kaposi's sarcoma shares macroscopic and histopathologic features with gastrointestinal stromal tumors. Correct diagnosis may pose a clinical challenge. We describe the case of a young HIV-1-infected African lady without advanced immunodeficiency, who presented with a diffuse spindle cell tumor of the gut. Initial diagnosis was of a gastrointestinal stromal tumor, based on endoscopy and histopathology. Further evaluation revealed evidence for human herpesvirus 8 (HHV8) and the diagnosis had to be changed to diffuse intestinal Kaposi's sarcoma. Antiretroviral triple therapy together with chemotherapy was commenced, and has led to the rapid remission of intestinal lesions. With a background of HIV infection, the presence of HHV8 as the causative agent of Kaposi's sarcoma should be determined, as distinct treatment is indicated.
AB - Diffuse intestinal Kaposi's sarcoma shares macroscopic and histopathologic features with gastrointestinal stromal tumors. Correct diagnosis may pose a clinical challenge. We describe the case of a young HIV-1-infected African lady without advanced immunodeficiency, who presented with a diffuse spindle cell tumor of the gut. Initial diagnosis was of a gastrointestinal stromal tumor, based on endoscopy and histopathology. Further evaluation revealed evidence for human herpesvirus 8 (HHV8) and the diagnosis had to be changed to diffuse intestinal Kaposi's sarcoma. Antiretroviral triple therapy together with chemotherapy was commenced, and has led to the rapid remission of intestinal lesions. With a background of HIV infection, the presence of HHV8 as the causative agent of Kaposi's sarcoma should be determined, as distinct treatment is indicated.
M3 - SCORING: Zeitschriftenaufsatz
VL - 13
SP - 4514
EP - 4516
JO - WORLD J GASTROENTERO
JF - WORLD J GASTROENTERO
SN - 1007-9327
IS - 33
M1 - 33
ER -
