Interrater agreement for final infarct MRI lesion delineation.
Standard
Interrater agreement for final infarct MRI lesion delineation. / Neumann, Anders B; Jonsdottir, Kristjana Y; Mouridsen, Kim; Hjort, Niels; Gyldensted, Carsten; Bizzi, Alberto; Fiehler, Jens; Gasparotti, Roberto; Gillard, Jonathan H; Hermier, Marc; Kucinski, Thomas; Larsson, Elna-Marie; Sørensen, Leif; Ostergaard, Leif.
In: STROKE, Vol. 40, No. 12, 12, 2009, p. 3768-3771.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Harvard
APA
Vancouver
Bibtex
}
RIS
TY - JOUR
T1 - Interrater agreement for final infarct MRI lesion delineation.
AU - Neumann, Anders B
AU - Jonsdottir, Kristjana Y
AU - Mouridsen, Kim
AU - Hjort, Niels
AU - Gyldensted, Carsten
AU - Bizzi, Alberto
AU - Fiehler, Jens
AU - Gasparotti, Roberto
AU - Gillard, Jonathan H
AU - Hermier, Marc
AU - Kucinski, Thomas
AU - Larsson, Elna-Marie
AU - Sørensen, Leif
AU - Ostergaard, Leif
PY - 2009
Y1 - 2009
N2 - BACKGROUND AND PURPOSE: Lesion volume measured on follow-up magnetic resonance imaging (MRI) is commonly used as an outcome parameter in clinical stroke trials. However, few studies have evaluated the optimal sequence choice and the interrater reliability of this outcome measure. The objective of this study was to quantify the geometric interrater agreement for lesion delineation of chronic infarcts on T2-weighted and fluid-attenuated inverse recovery (FLAIR) MRI. METHODS: In a retrospective study of 14 patients, lesions on 90-day follow-up FLAIR and T2 fast spin echo MRI were outlined by 9 independent, blinded, experienced neuroradiologists. Voxel-wise interrater agreement was measured as (1) the volume of the intersection of individual rater's lesion outlines relative to the mean lesion volume (overlap ratio) and (2) the Hausdorff distance between the lesion markings. RESULTS: Mean patient age was 64.4 years (range, 45 to 79). Lesion volumes on FLAIR were, on average, 2.5 mL greater than were T2 volumes (median; P
AB - BACKGROUND AND PURPOSE: Lesion volume measured on follow-up magnetic resonance imaging (MRI) is commonly used as an outcome parameter in clinical stroke trials. However, few studies have evaluated the optimal sequence choice and the interrater reliability of this outcome measure. The objective of this study was to quantify the geometric interrater agreement for lesion delineation of chronic infarcts on T2-weighted and fluid-attenuated inverse recovery (FLAIR) MRI. METHODS: In a retrospective study of 14 patients, lesions on 90-day follow-up FLAIR and T2 fast spin echo MRI were outlined by 9 independent, blinded, experienced neuroradiologists. Voxel-wise interrater agreement was measured as (1) the volume of the intersection of individual rater's lesion outlines relative to the mean lesion volume (overlap ratio) and (2) the Hausdorff distance between the lesion markings. RESULTS: Mean patient age was 64.4 years (range, 45 to 79). Lesion volumes on FLAIR were, on average, 2.5 mL greater than were T2 volumes (median; P
M3 - SCORING: Zeitschriftenaufsatz
VL - 40
SP - 3768
EP - 3771
JO - STROKE
JF - STROKE
SN - 0039-2499
IS - 12
M1 - 12
ER -