INSIGHT MM: a large, global, prospective, non-interventional, real-world study of patients with multiple myeloma

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INSIGHT MM: a large, global, prospective, non-interventional, real-world study of patients with multiple myeloma. / Costello, Caitlin; Davies, Faith E; Cook, Gordon; Vela-Ojeda, Jorge; Omel, Jim; Rifkin, Robert M; Berdeja, Jesus; Puig, Noemi; Usmani, Saad Z; Weisel, Katja; Zonder, Jeffrey A; Terpos, Evangelos; Spencer, Andrew; Leleu, Xavier; Boccadoro, Mario; Thompson, Michael A; Romanus, Dorothy; Stull, Dawn M; Hungria, Vania.

In: FUTURE ONCOL, Vol. 15, No. 13, 05.2019, p. 1411-1428.

Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

Harvard

Costello, C, Davies, FE, Cook, G, Vela-Ojeda, J, Omel, J, Rifkin, RM, Berdeja, J, Puig, N, Usmani, SZ, Weisel, K, Zonder, JA, Terpos, E, Spencer, A, Leleu, X, Boccadoro, M, Thompson, MA, Romanus, D, Stull, DM & Hungria, V 2019, 'INSIGHT MM: a large, global, prospective, non-interventional, real-world study of patients with multiple myeloma', FUTURE ONCOL, vol. 15, no. 13, pp. 1411-1428. https://doi.org/10.2217/fon-2019-0013

APA

Costello, C., Davies, F. E., Cook, G., Vela-Ojeda, J., Omel, J., Rifkin, R. M., Berdeja, J., Puig, N., Usmani, S. Z., Weisel, K., Zonder, J. A., Terpos, E., Spencer, A., Leleu, X., Boccadoro, M., Thompson, M. A., Romanus, D., Stull, D. M., & Hungria, V. (2019). INSIGHT MM: a large, global, prospective, non-interventional, real-world study of patients with multiple myeloma. FUTURE ONCOL, 15(13), 1411-1428. https://doi.org/10.2217/fon-2019-0013

Vancouver

Bibtex

@article{bad8f7a30ab4425e89e9cd505374ee6c,
title = "INSIGHT MM: a large, global, prospective, non-interventional, real-world study of patients with multiple myeloma",
abstract = "With the introduction of new drugs with different mechanisms of action, multiple myeloma (MM) patients' outcomes have improved. However, the efficacy seen in clinical trials is often not seen in real-world settings and data on the effectiveness of MM therapies are needed. INSIGHT MM is a prospective, global, non-interventional, observational study that is enrolling approximately 4200 patients with newly diagnosed or relapsed/refractory MM, making it the largest study of its kind to date. The study aims to describe contemporary, real-world patterns of patient characteristics, clinical disease presentation, therapies chosen, clinical outcomes (response, treatment duration, time-to-next-therapy, progression-free and overall survival), safety, healthcare resource utilization and quality of life. One interim analysis has been conducted to date; current accrual is approximately 3094 patients. Trial registration number: NCT02761187.",
keywords = "Journal Article",
author = "Caitlin Costello and Davies, {Faith E} and Gordon Cook and Jorge Vela-Ojeda and Jim Omel and Rifkin, {Robert M} and Jesus Berdeja and Noemi Puig and Usmani, {Saad Z} and Katja Weisel and Zonder, {Jeffrey A} and Evangelos Terpos and Andrew Spencer and Xavier Leleu and Mario Boccadoro and Thompson, {Michael A} and Dorothy Romanus and Stull, {Dawn M} and Vania Hungria",
year = "2019",
month = may,
doi = "10.2217/fon-2019-0013",
language = "English",
volume = "15",
pages = "1411--1428",
journal = "FUTURE ONCOL",
issn = "1479-6694",
publisher = "Future Medicine Ltd",
number = "13",

}

RIS

TY - JOUR

T1 - INSIGHT MM: a large, global, prospective, non-interventional, real-world study of patients with multiple myeloma

AU - Costello, Caitlin

AU - Davies, Faith E

AU - Cook, Gordon

AU - Vela-Ojeda, Jorge

AU - Omel, Jim

AU - Rifkin, Robert M

AU - Berdeja, Jesus

AU - Puig, Noemi

AU - Usmani, Saad Z

AU - Weisel, Katja

AU - Zonder, Jeffrey A

AU - Terpos, Evangelos

AU - Spencer, Andrew

AU - Leleu, Xavier

AU - Boccadoro, Mario

AU - Thompson, Michael A

AU - Romanus, Dorothy

AU - Stull, Dawn M

AU - Hungria, Vania

PY - 2019/5

Y1 - 2019/5

N2 - With the introduction of new drugs with different mechanisms of action, multiple myeloma (MM) patients' outcomes have improved. However, the efficacy seen in clinical trials is often not seen in real-world settings and data on the effectiveness of MM therapies are needed. INSIGHT MM is a prospective, global, non-interventional, observational study that is enrolling approximately 4200 patients with newly diagnosed or relapsed/refractory MM, making it the largest study of its kind to date. The study aims to describe contemporary, real-world patterns of patient characteristics, clinical disease presentation, therapies chosen, clinical outcomes (response, treatment duration, time-to-next-therapy, progression-free and overall survival), safety, healthcare resource utilization and quality of life. One interim analysis has been conducted to date; current accrual is approximately 3094 patients. Trial registration number: NCT02761187.

AB - With the introduction of new drugs with different mechanisms of action, multiple myeloma (MM) patients' outcomes have improved. However, the efficacy seen in clinical trials is often not seen in real-world settings and data on the effectiveness of MM therapies are needed. INSIGHT MM is a prospective, global, non-interventional, observational study that is enrolling approximately 4200 patients with newly diagnosed or relapsed/refractory MM, making it the largest study of its kind to date. The study aims to describe contemporary, real-world patterns of patient characteristics, clinical disease presentation, therapies chosen, clinical outcomes (response, treatment duration, time-to-next-therapy, progression-free and overall survival), safety, healthcare resource utilization and quality of life. One interim analysis has been conducted to date; current accrual is approximately 3094 patients. Trial registration number: NCT02761187.

KW - Journal Article

U2 - 10.2217/fon-2019-0013

DO - 10.2217/fon-2019-0013

M3 - SCORING: Journal article

C2 - 30816809

VL - 15

SP - 1411

EP - 1428

JO - FUTURE ONCOL

JF - FUTURE ONCOL

SN - 1479-6694

IS - 13

ER -