Influence of age, sex and hospitalisation on the administration of tuberculosis medication:
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Influence of age, sex and hospitalisation on the administration of tuberculosis medication: an evaluation of routine data from a German health insurer. / Kersten, Jan F; Wobbe-Ribinski, Stefanie; Diel, Roland; Nienhaus, Albert; Schablon, Anja.
In: ERJ OPEN RES, Vol. 6, No. 3, 07.2020.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
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TY - JOUR
T1 - Influence of age, sex and hospitalisation on the administration of tuberculosis medication:
T2 - an evaluation of routine data from a German health insurer
AU - Kersten, Jan F
AU - Wobbe-Ribinski, Stefanie
AU - Diel, Roland
AU - Nienhaus, Albert
AU - Schablon, Anja
N1 - Copyright ©ERS 2020.
PY - 2020/7
Y1 - 2020/7
N2 - Background: So far, there is no reliable information on the drugs actually taken by tuberculosis patients. With billing data from a large German health insurance company, valid data from practice will be used for analysis. The objective here is to use the claims data of a health insurer to gain an insight into the prescriptions issued to patients with tuberculosis in Germany.Methods: The study design encompasses a longitudinal, analytical observational study of selected insurance holders. Descriptive analyses of the outpatient drug supply of pulmonary tuberculosis patients are determined for 6 payroll years. We have studied whether different doses of tuberculosis medication are associated with age, sex, inpatient status and comorbidity. Quantile regression is used as a method to identify subgroups or characteristic dosages.Results: The number of defined daily doses prescribed per patient varies among insurance holders and encompasses widely differing timeframes. Higher doses are observed with increasing age, as well as in patients with tuberculosis-related hospitalisations. The sex of the patient has no identifiable effect on the prescribed doses for any of the first-line tuberculosis drugs. Comorbidity partially has a significant impact on the duration and intensity of tuberculosis drug prescriptions.
AB - Background: So far, there is no reliable information on the drugs actually taken by tuberculosis patients. With billing data from a large German health insurance company, valid data from practice will be used for analysis. The objective here is to use the claims data of a health insurer to gain an insight into the prescriptions issued to patients with tuberculosis in Germany.Methods: The study design encompasses a longitudinal, analytical observational study of selected insurance holders. Descriptive analyses of the outpatient drug supply of pulmonary tuberculosis patients are determined for 6 payroll years. We have studied whether different doses of tuberculosis medication are associated with age, sex, inpatient status and comorbidity. Quantile regression is used as a method to identify subgroups or characteristic dosages.Results: The number of defined daily doses prescribed per patient varies among insurance holders and encompasses widely differing timeframes. Higher doses are observed with increasing age, as well as in patients with tuberculosis-related hospitalisations. The sex of the patient has no identifiable effect on the prescribed doses for any of the first-line tuberculosis drugs. Comorbidity partially has a significant impact on the duration and intensity of tuberculosis drug prescriptions.
U2 - 10.1183/23120541.00369-2019
DO - 10.1183/23120541.00369-2019
M3 - SCORING: Journal article
C2 - 32743006
VL - 6
JO - ERJ OPEN RES
JF - ERJ OPEN RES
SN - 2312-0541
IS - 3
ER -
