Inflammatorische Erkrankungen mit Leber- und Gelenkbeteiligung. Eine differenzialdiagnostische Herausforderung
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Inflammatorische Erkrankungen mit Leber- und Gelenkbeteiligung. Eine differenzialdiagnostische Herausforderung. / Sebode, M; Schramm, C; Lohse, A W.
In: INTERNIST, Vol. 54, No. 4, 4, 2013, p. 441-448.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
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TY - JOUR
T1 - Inflammatorische Erkrankungen mit Leber- und Gelenkbeteiligung. Eine differenzialdiagnostische Herausforderung
AU - Sebode, M
AU - Schramm, C
AU - Lohse, A W
PY - 2013
Y1 - 2013
N2 - Elevated levels of liver enzymes in patients with rheumatic symptoms require a comprehensive differential diagnostic thought process. On the one hand there can be hepatic involvement of primarily rheumatological diseases but this is quite rare. Drug-induced liver injury by antirheumatic medication is more frequent. On the other hand arthralgia can be a sign of primary hepatopathy whereby hemochromatosis and autoimmune hepatitis (AIH) are typical examples. Furthermore, some liver diseases are associated with rheumatological diseases, such as primary biliary cirrhosis (PBC) and chronic hepatitis C infection (HCV). Only an exact diagnosis will lead to specific treatment which will improve the symptoms and course of disease.
AB - Elevated levels of liver enzymes in patients with rheumatic symptoms require a comprehensive differential diagnostic thought process. On the one hand there can be hepatic involvement of primarily rheumatological diseases but this is quite rare. Drug-induced liver injury by antirheumatic medication is more frequent. On the other hand arthralgia can be a sign of primary hepatopathy whereby hemochromatosis and autoimmune hepatitis (AIH) are typical examples. Furthermore, some liver diseases are associated with rheumatological diseases, such as primary biliary cirrhosis (PBC) and chronic hepatitis C infection (HCV). Only an exact diagnosis will lead to specific treatment which will improve the symptoms and course of disease.
KW - Arthritis
KW - Diagnosis, Differential
KW - Hepatitis
KW - Humans
KW - Systemic Inflammatory Response Syndrome
U2 - 10.1007/s00108-012-3191-6
DO - 10.1007/s00108-012-3191-6
M3 - SCORING: Zeitschriftenaufsatz
C2 - 23455625
VL - 54
SP - 441
EP - 448
JO - INTERNIST
JF - INTERNIST
SN - 0020-9554
IS - 4
M1 - 4
ER -