Inflammation and infections in asthma

Adrian Gillissen; Maria Paparoupa

doi:10.1111/crj.12135

Inflammation and infections in asthma

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Inflammation and infections in asthma. / Gillissen, Adrian; Paparoupa, Maria.

In: CLIN RESPIR J, Vol. 9, No. 3, 07.2015, p. 257-69.

Research output: SCORING: Contribution to journal › SCORING: Review article › Research

Harvard

Gillissen, A & Paparoupa, M 2015, 'Inflammation and infections in asthma', CLIN RESPIR J, vol. 9, no. 3, pp. 257-69. https://doi.org/10.1111/crj.12135

APA

Gillissen, A., & Paparoupa, M. (2015). Inflammation and infections in asthma. CLIN RESPIR J, 9(3), 257-69. https://doi.org/10.1111/crj.12135

Vancouver

Gillissen A, Paparoupa M. Inflammation and infections in asthma. CLIN RESPIR J. 2015 Jul;9(3):257-69. https://doi.org/10.1111/crj.12135

Bibtex

@article{1121ee8b6af64f57a134844d42805d3a,

title = "Inflammation and infections in asthma",

abstract = "INTRODUCTION: Asthma is driven by an inflammatory response against normally harmless environmental inorganic and organic compounds in the respiratory tract. Immune responses to airborne pathogens such as viruses and bacteria may reduce the allergic responses but are also known to trigger asthma attacks and eventually lead to severe disease condition.OBJECTIVE: To investigate the role of respiratory pathogens concerning the induction or protection against acute or chronic asthma manifestations.METHODS: We included 131 articles for the final review according to their relevance with the subject.RESULTS: There is apparently contradictory interaction of respiratory germs in the airways of asthmatics which may be protective on one angle but deleterious on the other.CONCLUSION: The relationship between inflammation and remodeling and the pathogenic role of viral and bacterial infection in the airways of asthmatic patients is still highly debatable and incompletely understood.",

keywords = "Airway Remodeling, Asthma, Humans, Inflammation, Respiratory Tract Infections, Journal Article, Review",

author = "Adrian Gillissen and Maria Paparoupa",

note = "{\textcopyright} 2014 John Wiley & Sons Ltd.",

year = "2015",

month = jul,

doi = "10.1111/crj.12135",

language = "English",

volume = "9",

pages = "257--69",

journal = "CLIN RESPIR J",

issn = "1752-6981",

publisher = "Wiley-Blackwell",

number = "3",

}

RIS

TY - JOUR

T1 - Inflammation and infections in asthma

AU - Gillissen, Adrian

AU - Paparoupa, Maria

PY - 2015/7

Y1 - 2015/7

N2 - INTRODUCTION: Asthma is driven by an inflammatory response against normally harmless environmental inorganic and organic compounds in the respiratory tract. Immune responses to airborne pathogens such as viruses and bacteria may reduce the allergic responses but are also known to trigger asthma attacks and eventually lead to severe disease condition.OBJECTIVE: To investigate the role of respiratory pathogens concerning the induction or protection against acute or chronic asthma manifestations.METHODS: We included 131 articles for the final review according to their relevance with the subject.RESULTS: There is apparently contradictory interaction of respiratory germs in the airways of asthmatics which may be protective on one angle but deleterious on the other.CONCLUSION: The relationship between inflammation and remodeling and the pathogenic role of viral and bacterial infection in the airways of asthmatic patients is still highly debatable and incompletely understood.

AB - INTRODUCTION: Asthma is driven by an inflammatory response against normally harmless environmental inorganic and organic compounds in the respiratory tract. Immune responses to airborne pathogens such as viruses and bacteria may reduce the allergic responses but are also known to trigger asthma attacks and eventually lead to severe disease condition.OBJECTIVE: To investigate the role of respiratory pathogens concerning the induction or protection against acute or chronic asthma manifestations.METHODS: We included 131 articles for the final review according to their relevance with the subject.RESULTS: There is apparently contradictory interaction of respiratory germs in the airways of asthmatics which may be protective on one angle but deleterious on the other.CONCLUSION: The relationship between inflammation and remodeling and the pathogenic role of viral and bacterial infection in the airways of asthmatic patients is still highly debatable and incompletely understood.

KW - Airway Remodeling

KW - Asthma

KW - Humans

KW - Inflammation

KW - Respiratory Tract Infections

KW - Journal Article

KW - Review

U2 - 10.1111/crj.12135

DO - 10.1111/crj.12135

M3 - SCORING: Review article

C2 - 24725460

VL - 9

SP - 257

EP - 269

JO - CLIN RESPIR J

JF - CLIN RESPIR J

SN - 1752-6981

IS - 3

ER -