Individual patient data meta-analysis shows no association between the SNP rs1800469 in TGFB and late radiotherapy toxicity.
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Individual patient data meta-analysis shows no association between the SNP rs1800469 in TGFB and late radiotherapy toxicity. / Barnett, Gillian C; Elliott, Rebecca M; Alsner, Jan; Andreassen, Christian N; Abdelhay, Osama; Burnet, Neil G; Chang-Claude, Jenny; Coles, Charlotte E; Gutiérrez-Enríquez, Sara; Fuentes-Raspall, Maria J; Alonso-Muñoz, Maria C; Kerns, Sarah; Raabe, Annette; Symonds, R Paul; Seibold, Petra; Talbot, Chris J; Wenz, Frederik; Wilkinson, Jennifer; Yarnold, John; Dunning, Alison M; Rosenstein, Barry S; West, Catharine M L; Bentzen, Søren M.
In: RADIOTHER ONCOL, Vol. 105, No. 3, 3, 2012, p. 289-295.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
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TY - JOUR
T1 - Individual patient data meta-analysis shows no association between the SNP rs1800469 in TGFB and late radiotherapy toxicity.
AU - Barnett, Gillian C
AU - Elliott, Rebecca M
AU - Alsner, Jan
AU - Andreassen, Christian N
AU - Abdelhay, Osama
AU - Burnet, Neil G
AU - Chang-Claude, Jenny
AU - Coles, Charlotte E
AU - Gutiérrez-Enríquez, Sara
AU - Fuentes-Raspall, Maria J
AU - Alonso-Muñoz, Maria C
AU - Kerns, Sarah
AU - Raabe, Annette
AU - Symonds, R Paul
AU - Seibold, Petra
AU - Talbot, Chris J
AU - Wenz, Frederik
AU - Wilkinson, Jennifer
AU - Yarnold, John
AU - Dunning, Alison M
AU - Rosenstein, Barry S
AU - West, Catharine M L
AU - Bentzen, Søren M
PY - 2012
Y1 - 2012
N2 - Reported associations between risk of radiation-induced normal tissue injury and single nucleotide polymorphisms (SNPs) in TGFB1, encoding the pro-fibrotic cytokine transforming growth factor-beta 1 (TGF-?1), remain controversial. To overcome publication bias, the international Radiogenomics Consortium collected and analysed individual patient level data from both published and unpublished studies.
AB - Reported associations between risk of radiation-induced normal tissue injury and single nucleotide polymorphisms (SNPs) in TGFB1, encoding the pro-fibrotic cytokine transforming growth factor-beta 1 (TGF-?1), remain controversial. To overcome publication bias, the international Radiogenomics Consortium collected and analysed individual patient level data from both published and unpublished studies.
KW - Humans
KW - Genotype
KW - Odds Ratio
KW - Alleles
KW - Risk
KW - Linear Models
KW - Polymorphism, Single Nucleotide
KW - Radiotherapy, Adjuvant/adverse effects
KW - Radiation Tolerance/genetics
KW - Breast Neoplasms/genetics/pathology/radiotherapy
KW - Fibrosis/etiology
KW - Radiation Injuries/genetics
KW - Transforming Growth Factor beta1/genetics
KW - Humans
KW - Genotype
KW - Odds Ratio
KW - Alleles
KW - Risk
KW - Linear Models
KW - Polymorphism, Single Nucleotide
KW - Radiotherapy, Adjuvant/adverse effects
KW - Radiation Tolerance/genetics
KW - Breast Neoplasms/genetics/pathology/radiotherapy
KW - Fibrosis/etiology
KW - Radiation Injuries/genetics
KW - Transforming Growth Factor beta1/genetics
M3 - SCORING: Journal article
VL - 105
SP - 289
EP - 295
JO - RADIOTHER ONCOL
JF - RADIOTHER ONCOL
SN - 0167-8140
IS - 3
M1 - 3
ER -