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Increasing rates of NCCN high and very high-risk prostate cancer versus number of prostate biopsy cores

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Increasing rates of NCCN high and very high-risk prostate cancer versus number of prostate biopsy cores. / Wenzel, Mike; Würnschimmel, Christoph; Ruvolo, Claudia C; Nocera, Luigi; Tian, Zhe; Saad, Fred; Briganti, Alberto; Tilki, Derya; Graefen, Markus; Kluth, Luis A; Mandel, Philipp; Chun, Felix K H; Karakiewicz, Pierre I.

In: PROSTATE, Vol. 81, No. 12, 09.2021, p. 874-881.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Wenzel, M, Würnschimmel, C, Ruvolo, CC, Nocera, L, Tian, Z, Saad, F, Briganti, A, Tilki, D, Graefen, M, Kluth, LA, Mandel, P, Chun, FKH & Karakiewicz, PI 2021, 'Increasing rates of NCCN high and very high-risk prostate cancer versus number of prostate biopsy cores', PROSTATE, vol. 81, no. 12, pp. 874-881. https://doi.org/10.1002/pros.24184

APA

Wenzel, M., Würnschimmel, C., Ruvolo, C. C., Nocera, L., Tian, Z., Saad, F., Briganti, A., Tilki, D., Graefen, M., Kluth, L. A., Mandel, P., Chun, F. K. H., & Karakiewicz, P. I. (2021). Increasing rates of NCCN high and very high-risk prostate cancer versus number of prostate biopsy cores. PROSTATE, 81(12), 874-881. https://doi.org/10.1002/pros.24184

Vancouver

Wenzel M, Würnschimmel C, Ruvolo CC, Nocera L, Tian Z, Saad F et al. Increasing rates of NCCN high and very high-risk prostate cancer versus number of prostate biopsy cores. PROSTATE. 2021 Sep;81(12):874-881. https://doi.org/10.1002/pros.24184

Bibtex

@article{3edc37f040c047ca949b06351eb984bd,
title = "Increasing rates of NCCN high and very high-risk prostate cancer versus number of prostate biopsy cores",
abstract = "BACKGROUND: Recently, an increase in the rates of high-risk prostate cancer (PCa) was reported. We tested whether the rates of and low, intermediate, high and very high-risk PCa changed over time. We also tested whether the number of prostate biopsy cores contributed to changes rates over time.METHODS: Within the Surveillance, Epidemiology and End Results (SEER) database (2010-2015), annual rates of low, intermediate, high-risk according to traditional National Comprehensive Cancer Network (NCCN) and high versus very high-risk PCa according to Johns Hopkins classification were tabulated without and with adjustment for the number of prostate biopsy cores.RESULTS: In 119,574 eligible prostate cancer patients, the rates of NCCN low, intermediate, and high-risk PCa were, respectively, 29.7%, 47.8%, and 22.5%. Of high-risk patients, 39.6% and 60.4% fulfilled high and very high-risk criteria. Without adjustment for number of prostate biopsy cores, the estimated annual percentage changes (EAPC) for low, intermediate, high and very high-risk were respectively -5.5% (32.4%-24.9%, p < .01), +0.5% (47.6%-48.4%, p = .09), +4.1% (8.2%-9.9%, p < .01), and +8.9% (11.8%-16.9%, p < .01), between 2010 and 2015. After adjustment for number of prostate biopsy cores, differences in rates over time disappeared and ranged from 29.8%-29.7% for low risk, 47.9%-47.9% for intermediate risk, 8.9%-9.0% for high-risk, and 13.6%-13.6% for very high-risk PCa (all p > .05).CONCLUSIONS: The rates of high and very high-risk PCa are strongly associated with the number of prostate biopsy cores, that in turn may be driven by broader use magnetic resonance imaging (MRI).",
author = "Mike Wenzel and Christoph W{\"u}rnschimmel and Ruvolo, {Claudia C} and Luigi Nocera and Zhe Tian and Fred Saad and Alberto Briganti and Derya Tilki and Markus Graefen and Kluth, {Luis A} and Philipp Mandel and Chun, {Felix K H} and Karakiewicz, {Pierre I}",
note = "{\textcopyright} 2021 The Authors. The Prostate published by Wiley Periodicals LLC.",
year = "2021",
month = sep,
doi = "10.1002/pros.24184",
language = "English",
volume = "81",
pages = "874--881",
journal = "PROSTATE",
issn = "0270-4137",
publisher = "Wiley-Liss Inc.",
number = "12",

}

RIS

TY - JOUR

T1 - Increasing rates of NCCN high and very high-risk prostate cancer versus number of prostate biopsy cores

AU - Wenzel, Mike

AU - Würnschimmel, Christoph

AU - Ruvolo, Claudia C

AU - Nocera, Luigi

AU - Tian, Zhe

AU - Saad, Fred

AU - Briganti, Alberto

AU - Tilki, Derya

AU - Graefen, Markus

AU - Kluth, Luis A

AU - Mandel, Philipp

AU - Chun, Felix K H

AU - Karakiewicz, Pierre I

N1 - © 2021 The Authors. The Prostate published by Wiley Periodicals LLC.

PY - 2021/9

Y1 - 2021/9

N2 - BACKGROUND: Recently, an increase in the rates of high-risk prostate cancer (PCa) was reported. We tested whether the rates of and low, intermediate, high and very high-risk PCa changed over time. We also tested whether the number of prostate biopsy cores contributed to changes rates over time.METHODS: Within the Surveillance, Epidemiology and End Results (SEER) database (2010-2015), annual rates of low, intermediate, high-risk according to traditional National Comprehensive Cancer Network (NCCN) and high versus very high-risk PCa according to Johns Hopkins classification were tabulated without and with adjustment for the number of prostate biopsy cores.RESULTS: In 119,574 eligible prostate cancer patients, the rates of NCCN low, intermediate, and high-risk PCa were, respectively, 29.7%, 47.8%, and 22.5%. Of high-risk patients, 39.6% and 60.4% fulfilled high and very high-risk criteria. Without adjustment for number of prostate biopsy cores, the estimated annual percentage changes (EAPC) for low, intermediate, high and very high-risk were respectively -5.5% (32.4%-24.9%, p < .01), +0.5% (47.6%-48.4%, p = .09), +4.1% (8.2%-9.9%, p < .01), and +8.9% (11.8%-16.9%, p < .01), between 2010 and 2015. After adjustment for number of prostate biopsy cores, differences in rates over time disappeared and ranged from 29.8%-29.7% for low risk, 47.9%-47.9% for intermediate risk, 8.9%-9.0% for high-risk, and 13.6%-13.6% for very high-risk PCa (all p > .05).CONCLUSIONS: The rates of high and very high-risk PCa are strongly associated with the number of prostate biopsy cores, that in turn may be driven by broader use magnetic resonance imaging (MRI).

AB - BACKGROUND: Recently, an increase in the rates of high-risk prostate cancer (PCa) was reported. We tested whether the rates of and low, intermediate, high and very high-risk PCa changed over time. We also tested whether the number of prostate biopsy cores contributed to changes rates over time.METHODS: Within the Surveillance, Epidemiology and End Results (SEER) database (2010-2015), annual rates of low, intermediate, high-risk according to traditional National Comprehensive Cancer Network (NCCN) and high versus very high-risk PCa according to Johns Hopkins classification were tabulated without and with adjustment for the number of prostate biopsy cores.RESULTS: In 119,574 eligible prostate cancer patients, the rates of NCCN low, intermediate, and high-risk PCa were, respectively, 29.7%, 47.8%, and 22.5%. Of high-risk patients, 39.6% and 60.4% fulfilled high and very high-risk criteria. Without adjustment for number of prostate biopsy cores, the estimated annual percentage changes (EAPC) for low, intermediate, high and very high-risk were respectively -5.5% (32.4%-24.9%, p < .01), +0.5% (47.6%-48.4%, p = .09), +4.1% (8.2%-9.9%, p < .01), and +8.9% (11.8%-16.9%, p < .01), between 2010 and 2015. After adjustment for number of prostate biopsy cores, differences in rates over time disappeared and ranged from 29.8%-29.7% for low risk, 47.9%-47.9% for intermediate risk, 8.9%-9.0% for high-risk, and 13.6%-13.6% for very high-risk PCa (all p > .05).CONCLUSIONS: The rates of high and very high-risk PCa are strongly associated with the number of prostate biopsy cores, that in turn may be driven by broader use magnetic resonance imaging (MRI).

U2 - 10.1002/pros.24184

DO - 10.1002/pros.24184

M3 - SCORING: Journal article

C2 - 34184780

VL - 81

SP - 874

EP - 881

JO - PROSTATE

JF - PROSTATE

SN - 0270-4137

IS - 12

ER -