Incidence and timing of serious arrhythmias after early revascularization in non ST-elevation myocardial infarction
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Incidence and timing of serious arrhythmias after early revascularization in non ST-elevation myocardial infarction. / Wildi, Karin; Cuculi, Florim; Twerenbold, Raphael; Marxer, Tanja; Rubini Gimenez, Maria; Reichlin, Tobias; Haaf, Philip; Monsch, Raphael; Marsch, Stefan; Hunziker, Patrick; Bingisser, Roland; Osswald, Stefan; Erne, Paul; Mueller, Christian.
In: EUR HEART J-ACUTE CA, Vol. 4, No. 4, 01.08.2015, p. 359-364.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
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TY - JOUR
T1 - Incidence and timing of serious arrhythmias after early revascularization in non ST-elevation myocardial infarction
AU - Wildi, Karin
AU - Cuculi, Florim
AU - Twerenbold, Raphael
AU - Marxer, Tanja
AU - Rubini Gimenez, Maria
AU - Reichlin, Tobias
AU - Haaf, Philip
AU - Monsch, Raphael
AU - Marsch, Stefan
AU - Hunziker, Patrick
AU - Bingisser, Roland
AU - Osswald, Stefan
AU - Erne, Paul
AU - Mueller, Christian
N1 - Publisher Copyright: © The European Society of Cardiology 2014.
PY - 2015/8/1
Y1 - 2015/8/1
N2 - BACKGROUND: In contrast to ST-elevation myocardial infarction (STEMI), in non-STEMI (NSTEMI) patients the need for continuous rhythm monitoring in a coronary care unit, respective incidence and timing of serious arrhythmias are poorly defined.METHODS: We used a derivation-validation design and data from two independent prospective cohorts of consecutive haemodynamically stable NSTEMI patients to evaluate the incidence and timing of serious arrhythmias after successful early percutaneous revascularization. Serious arrhythmia was prospectively defined as any arrhythmia that requires immediate medical attention including persistent ventricular tachycardia (>30 s), ventricular fibrillation, asystole, and high degree atrioventricular (AV)-block requiring pacemaker insertion during hospitalization.RESULTS: In the derivation cohort, among 228 NSTEMI patients who underwent successful early percutaneous revascularization, one patient (0.4%, 95% confidence interval 0.02-2.8%) had a serious arrhythmia which occurred 21 h after revascularization. In the validation cohort, among 293 NSTEMI patients who underwent successful early percutaneous revascularization, no patient (0%, 95% confidence interval 0-1.6%) had a serious arrhythmia after revascularization.CONCLUSION: The incidence of serious arrhythmias in NSTEMI patients after successful early revascularization seems to be very low.
AB - BACKGROUND: In contrast to ST-elevation myocardial infarction (STEMI), in non-STEMI (NSTEMI) patients the need for continuous rhythm monitoring in a coronary care unit, respective incidence and timing of serious arrhythmias are poorly defined.METHODS: We used a derivation-validation design and data from two independent prospective cohorts of consecutive haemodynamically stable NSTEMI patients to evaluate the incidence and timing of serious arrhythmias after successful early percutaneous revascularization. Serious arrhythmia was prospectively defined as any arrhythmia that requires immediate medical attention including persistent ventricular tachycardia (>30 s), ventricular fibrillation, asystole, and high degree atrioventricular (AV)-block requiring pacemaker insertion during hospitalization.RESULTS: In the derivation cohort, among 228 NSTEMI patients who underwent successful early percutaneous revascularization, one patient (0.4%, 95% confidence interval 0.02-2.8%) had a serious arrhythmia which occurred 21 h after revascularization. In the validation cohort, among 293 NSTEMI patients who underwent successful early percutaneous revascularization, no patient (0%, 95% confidence interval 0-1.6%) had a serious arrhythmia after revascularization.CONCLUSION: The incidence of serious arrhythmias in NSTEMI patients after successful early revascularization seems to be very low.
KW - coronary care unit
KW - monitoring
KW - NSTEMI
KW - serious arrhythmia
KW - successful revascularization
UR - http://www.scopus.com/inward/record.url?scp=84998085999&partnerID=8YFLogxK
U2 - 10.1177/2048872614557230
DO - 10.1177/2048872614557230
M3 - SCORING: Journal article
C2 - 25348273
AN - SCOPUS:84998085999
VL - 4
SP - 359
EP - 364
JO - EUR HEART J-ACUTE CA
JF - EUR HEART J-ACUTE CA
SN - 2048-8726
IS - 4
ER -