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In the Search of Marine Pestiviruses:First Case of Phocoena Pestivirus in a Belt Sea Harbour Porpoise

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In the Search of Marine Pestiviruses:First Case of Phocoena Pestivirus in a Belt Sea Harbour Porpoise. / Stokholm, Iben; Fischer, Nicole; Baechlein, Christine; Postel, Alexander; Galatius, Anders; Kyhn, Line Anker; Thøstesen, Charlotte Bie; Persson, Sara; Siebert, Ursula; Olsen, Morten Tange; Becher, Paul.

In: VIRUSES-BASEL, Vol. 14, No. 1, 161, 17.01.2022.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Stokholm, I, Fischer, N, Baechlein, C, Postel, A, Galatius, A, Kyhn, LA, Thøstesen, CB, Persson, S, Siebert, U, Olsen, MT & Becher, P 2022, 'In the Search of Marine Pestiviruses:First Case of Phocoena Pestivirus in a Belt Sea Harbour Porpoise', VIRUSES-BASEL, vol. 14, no. 1, 161. https://doi.org/10.3390/v14010161

APA

Stokholm, I., Fischer, N., Baechlein, C., Postel, A., Galatius, A., Kyhn, L. A., Thøstesen, C. B., Persson, S., Siebert, U., Olsen, M. T., & Becher, P. (2022). In the Search of Marine Pestiviruses:First Case of Phocoena Pestivirus in a Belt Sea Harbour Porpoise. VIRUSES-BASEL, 14(1), [161]. https://doi.org/10.3390/v14010161

Vancouver

Stokholm I, Fischer N, Baechlein C, Postel A, Galatius A, Kyhn LA et al. In the Search of Marine Pestiviruses:First Case of Phocoena Pestivirus in a Belt Sea Harbour Porpoise. VIRUSES-BASEL. 2022 Jan 17;14(1). 161. https://doi.org/10.3390/v14010161

Bibtex

@article{6d1a8d055036484d98785226b8928c2b,
title = "In the Search of Marine Pestiviruses:First Case of Phocoena Pestivirus in a Belt Sea Harbour Porpoise",
abstract = "Pestiviruses are widespread pathogens causing severe acute and chronic diseases among terrestrial mammals. Recently, Phocoena pestivirus (PhoPeV) was described in harbour porpoises (Phocoena phocoena) of the North Sea, expanding the host range to marine mammals. While the role of the virus is unknown, intrauterine infections with the most closely related pestiviruses- Bungowannah pestivirus (BuPV) and Linda virus (LindaV)-can cause increased rates of abortions and deaths in young piglets. Such diseases could severely impact already vulnerable harbour porpoise populations. Here, we investigated the presence of PhoPeV in 77 harbour porpoises, 277 harbour seals (Phoca vitulina), grey seals (Halichoerus grypus) and ringed seals (Pusa hispida) collected in the Baltic Sea region between 2002 and 2019. The full genome sequence of a pestivirus was obtained from a juvenile female porpoise collected along the coast of Zealand in Denmark in 2011. The comparative Bayesian phylogenetic analyses revealed a close relationship between the new PhoPeV sequence and previously published North Sea sequences with a recent divergence from genotype 1 sequences between 2005 and 2009. Our findings provide further insight into the circulation of PhoPeV and expand the distribution from the North Sea to the Baltic Sea region with possible implications for the vulnerable Belt Sea and endangered Baltic Proper harbour porpoise populations.",
keywords = "Animals, Bayes Theorem, Denmark, Female, Host Specificity, Oceans and Seas, Pestivirus/classification, Phoca/virology, Phylogeny",
author = "Iben Stokholm and Nicole Fischer and Christine Baechlein and Alexander Postel and Anders Galatius and Kyhn, {Line Anker} and Th{\o}stesen, {Charlotte Bie} and Sara Persson and Ursula Siebert and Olsen, {Morten Tange} and Paul Becher",
year = "2022",
month = jan,
day = "17",
doi = "10.3390/v14010161",
language = "English",
volume = "14",
journal = "VIRUSES-BASEL",
issn = "1999-4915",
publisher = "Multidisciplinary Digital Publishing Institute (MDPI)",
number = "1",

}

RIS

TY - JOUR

T1 - In the Search of Marine Pestiviruses:First Case of Phocoena Pestivirus in a Belt Sea Harbour Porpoise

AU - Stokholm, Iben

AU - Fischer, Nicole

AU - Baechlein, Christine

AU - Postel, Alexander

AU - Galatius, Anders

AU - Kyhn, Line Anker

AU - Thøstesen, Charlotte Bie

AU - Persson, Sara

AU - Siebert, Ursula

AU - Olsen, Morten Tange

AU - Becher, Paul

PY - 2022/1/17

Y1 - 2022/1/17

N2 - Pestiviruses are widespread pathogens causing severe acute and chronic diseases among terrestrial mammals. Recently, Phocoena pestivirus (PhoPeV) was described in harbour porpoises (Phocoena phocoena) of the North Sea, expanding the host range to marine mammals. While the role of the virus is unknown, intrauterine infections with the most closely related pestiviruses- Bungowannah pestivirus (BuPV) and Linda virus (LindaV)-can cause increased rates of abortions and deaths in young piglets. Such diseases could severely impact already vulnerable harbour porpoise populations. Here, we investigated the presence of PhoPeV in 77 harbour porpoises, 277 harbour seals (Phoca vitulina), grey seals (Halichoerus grypus) and ringed seals (Pusa hispida) collected in the Baltic Sea region between 2002 and 2019. The full genome sequence of a pestivirus was obtained from a juvenile female porpoise collected along the coast of Zealand in Denmark in 2011. The comparative Bayesian phylogenetic analyses revealed a close relationship between the new PhoPeV sequence and previously published North Sea sequences with a recent divergence from genotype 1 sequences between 2005 and 2009. Our findings provide further insight into the circulation of PhoPeV and expand the distribution from the North Sea to the Baltic Sea region with possible implications for the vulnerable Belt Sea and endangered Baltic Proper harbour porpoise populations.

AB - Pestiviruses are widespread pathogens causing severe acute and chronic diseases among terrestrial mammals. Recently, Phocoena pestivirus (PhoPeV) was described in harbour porpoises (Phocoena phocoena) of the North Sea, expanding the host range to marine mammals. While the role of the virus is unknown, intrauterine infections with the most closely related pestiviruses- Bungowannah pestivirus (BuPV) and Linda virus (LindaV)-can cause increased rates of abortions and deaths in young piglets. Such diseases could severely impact already vulnerable harbour porpoise populations. Here, we investigated the presence of PhoPeV in 77 harbour porpoises, 277 harbour seals (Phoca vitulina), grey seals (Halichoerus grypus) and ringed seals (Pusa hispida) collected in the Baltic Sea region between 2002 and 2019. The full genome sequence of a pestivirus was obtained from a juvenile female porpoise collected along the coast of Zealand in Denmark in 2011. The comparative Bayesian phylogenetic analyses revealed a close relationship between the new PhoPeV sequence and previously published North Sea sequences with a recent divergence from genotype 1 sequences between 2005 and 2009. Our findings provide further insight into the circulation of PhoPeV and expand the distribution from the North Sea to the Baltic Sea region with possible implications for the vulnerable Belt Sea and endangered Baltic Proper harbour porpoise populations.

KW - Animals

KW - Bayes Theorem

KW - Denmark

KW - Female

KW - Host Specificity

KW - Oceans and Seas

KW - Pestivirus/classification

KW - Phoca/virology

KW - Phylogeny

U2 - 10.3390/v14010161

DO - 10.3390/v14010161

M3 - SCORING: Journal article

C2 - 35062365

VL - 14

JO - VIRUSES-BASEL

JF - VIRUSES-BASEL

SN - 1999-4915

IS - 1

M1 - 161

ER -