Improved agreement between experienced and inexperienced observers using a standardized evaluation protocol for cardiac volumetry and infarct size measurement
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Improved agreement between experienced and inexperienced observers using a standardized evaluation protocol for cardiac volumetry and infarct size measurement. / Groth, M; Muellerleile, K; Klink, T; Säring, D; Halaj, S; Folwarski, G; Kaul, M; Bannas, P; Adam, G; Lund, G K.
In: ROFO-FORTSCHR RONTG, Vol. 184, No. 12, 12, 12.2012, p. 1131-1137.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
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TY - JOUR
T1 - Improved agreement between experienced and inexperienced observers using a standardized evaluation protocol for cardiac volumetry and infarct size measurement
AU - Groth, M
AU - Muellerleile, K
AU - Klink, T
AU - Säring, D
AU - Halaj, S
AU - Folwarski, G
AU - Kaul, M
AU - Bannas, P
AU - Adam, G
AU - Lund, G K
N1 - © Georg Thieme Verlag KG Stuttgart · New York.
PY - 2012/12
Y1 - 2012/12
N2 - PURPOSE: To study the agreement between experienced and inexperienced observers before and after training using a standardized evaluation protocol for cardiac magnetic resonance imaging (CMR) measurements of left ventricular (LV) volumes, mass and infarct size.MATERIALS AND METHODS: First, 10 CMR studies from patients with myocardial infarction were analyzed by 2 experienced and 4 inexperienced observers in respect to end-diastolic volume (EDV), end-systolic volume (ESV), ejection fraction (EF), LV mass and infarct size. Subsequently, the inexperienced observers were trained using a standardized evaluation protocol. Thereafter, all observers analyzed another 10 CMR studies.RESULTS: Before training the relative difference between experienced and inexperienced observers was -4.3±8.2% for EDV, -13.3±14.2% for ESV, 5.9±8.2% for EF, -12.2±10.9% for LV mass and -27.0±29.0% for infarct size in gram. After training, agreement significantly improved to 0.2±8.8% for EDV (p<0.05), -2.1±10.9 for ESV (p<0.01), 1.5±6.9% for EF (p<0.05), and -3.6±17.1% for infarct size (p<0.0001), but no improvement was seen for LV mass (-11.2±7.9, p=0.64). A slice based analysis showed, that the variable inclusion of the most basal and apical slices were mainly responsible for the low agreement of the measurements before training.CONCLUSION: Training using a standardized evaluation protocol significantly improved the agreement between experienced and inexperienced observers for important CMR parameters. The proposed evaluation protocol can be used for training to improve the reproducibility of CMR measurements.
AB - PURPOSE: To study the agreement between experienced and inexperienced observers before and after training using a standardized evaluation protocol for cardiac magnetic resonance imaging (CMR) measurements of left ventricular (LV) volumes, mass and infarct size.MATERIALS AND METHODS: First, 10 CMR studies from patients with myocardial infarction were analyzed by 2 experienced and 4 inexperienced observers in respect to end-diastolic volume (EDV), end-systolic volume (ESV), ejection fraction (EF), LV mass and infarct size. Subsequently, the inexperienced observers were trained using a standardized evaluation protocol. Thereafter, all observers analyzed another 10 CMR studies.RESULTS: Before training the relative difference between experienced and inexperienced observers was -4.3±8.2% for EDV, -13.3±14.2% for ESV, 5.9±8.2% for EF, -12.2±10.9% for LV mass and -27.0±29.0% for infarct size in gram. After training, agreement significantly improved to 0.2±8.8% for EDV (p<0.05), -2.1±10.9 for ESV (p<0.01), 1.5±6.9% for EF (p<0.05), and -3.6±17.1% for infarct size (p<0.0001), but no improvement was seen for LV mass (-11.2±7.9, p=0.64). A slice based analysis showed, that the variable inclusion of the most basal and apical slices were mainly responsible for the low agreement of the measurements before training.CONCLUSION: Training using a standardized evaluation protocol significantly improved the agreement between experienced and inexperienced observers for important CMR parameters. The proposed evaluation protocol can be used for training to improve the reproducibility of CMR measurements.
KW - Germany
KW - Humans
KW - Male
KW - Aged
KW - Female
KW - Middle Aged
KW - Reference Standards
KW - Reproducibility of Results
KW - Prognosis
KW - Observer Variation
KW - Magnetic Resonance Imaging/methods
KW - Image Interpretation, Computer-Assisted/methods
KW - Stroke Volume/physiology
KW - Systole/physiology
KW - Curriculum
KW - Diastole/physiology
KW - Students, Medical
KW - Cardiac Volume/physiology
KW - Cardiology/education
KW - Heart Ventricles/pathology
KW - Inservice Training
KW - Internship and Residency
KW - Myocardial Infarction/classification/diagnosis
KW - Papillary Muscles/pathology
KW - Radiology/education
KW - Germany
KW - Humans
KW - Male
KW - Aged
KW - Female
KW - Middle Aged
KW - Reference Standards
KW - Reproducibility of Results
KW - Prognosis
KW - Observer Variation
KW - Magnetic Resonance Imaging/methods
KW - Image Interpretation, Computer-Assisted/methods
KW - Stroke Volume/physiology
KW - Systole/physiology
KW - Curriculum
KW - Diastole/physiology
KW - Students, Medical
KW - Cardiac Volume/physiology
KW - Cardiology/education
KW - Heart Ventricles/pathology
KW - Inservice Training
KW - Internship and Residency
KW - Myocardial Infarction/classification/diagnosis
KW - Papillary Muscles/pathology
KW - Radiology/education
U2 - 10.1055/s-0032-1313171
DO - 10.1055/s-0032-1313171
M3 - SCORING: Journal article
C2 - 23023228
VL - 184
SP - 1131
EP - 1137
JO - ROFO-FORTSCHR RONTG
JF - ROFO-FORTSCHR RONTG
SN - 1438-9029
IS - 12
M1 - 12
ER -