Implication of gender differences in heroin-assisted treatment: results from the German randomized controlled trial.
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Implication of gender differences in heroin-assisted treatment: results from the German randomized controlled trial. / Eiroa-Orosa, Francisco Jose; Verthein, Uwe; Kuhn, Silke; Lindemann, Christina; Karow, Anne; Haasen, Christian; Reimer, Jens.
In: AM J ADDICTION, Vol. 19, No. 4, 4, 2010, p. 312-318.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
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TY - JOUR
T1 - Implication of gender differences in heroin-assisted treatment: results from the German randomized controlled trial.
AU - Eiroa-Orosa, Francisco Jose
AU - Verthein, Uwe
AU - Kuhn, Silke
AU - Lindemann, Christina
AU - Karow, Anne
AU - Haasen, Christian
AU - Reimer, Jens
PY - 2010
Y1 - 2010
N2 - Despite a lower prevalence of opioid dependence among females, drug-related problems and risk factors such as prostitution have a negative effect for women in treatment. This study was conducted with the purpose of analyzing gender differences in the German trial on heroin-assisted treatment (HAT), which compared HAT with methadone maintenance treatment (MMT). Significant baseline gender differences were found, with females showing a greater extent of mental distress. Differences in retention and outcome were significant for male patients, but no differences between treatment options were found for female patients. Ongoing prostitution was found to influence drug use outcomes. Other outcome criteria may need to be stressed when assessing the effect of HAT for women.
AB - Despite a lower prevalence of opioid dependence among females, drug-related problems and risk factors such as prostitution have a negative effect for women in treatment. This study was conducted with the purpose of analyzing gender differences in the German trial on heroin-assisted treatment (HAT), which compared HAT with methadone maintenance treatment (MMT). Significant baseline gender differences were found, with females showing a greater extent of mental distress. Differences in retention and outcome were significant for male patients, but no differences between treatment options were found for female patients. Ongoing prostitution was found to influence drug use outcomes. Other outcome criteria may need to be stressed when assessing the effect of HAT for women.
KW - Adult
KW - Female
KW - Germany
KW - Heroin
KW - Humans
KW - Male
KW - Medication Adherence
KW - Methadone
KW - Narcotics
KW - Opioid-Related Disorders
KW - Prostitution
KW - Sex Characteristics
U2 - 10.1111/j.1521-0391.2010.00049.x
DO - 10.1111/j.1521-0391.2010.00049.x
M3 - SCORING: Journal article
C2 - 20653637
VL - 19
SP - 312
EP - 318
JO - AM J ADDICTION
JF - AM J ADDICTION
SN - 1055-0496
IS - 4
M1 - 4
ER -