Impaired melanoma growth in VASP deficient mice.
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Abstract
Progression of tumors depends on interactions of cancer cells with the host environment. Expression of the cytoskeleton protein VASP is upregulated in various cancer entities. We analyzed the role of VASP for melanoma growth in murine allograft models. Growth of VASP expressing melanomas was retarded in VASP(-/-) versus wild-type animals. Over time tumor size was
Bibliographical data
| Original language | English |
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| Article number | 15 |
| ISSN | 0014-5793 |
| Publication status | Published - 2011 |
| pubmed | 21762694 |
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