Impaired LDL receptor-related protein 1 translocation correlates with improved dyslipidemia and atherosclerosis in apoE-deficient mice.

Philip L S M Gordts; Alexander Bartelt; Stefan K Nilsson; Wim Annaert; Christina Christoffersen; Lars Bo Nielsen; Jörg Heeren; Anton J M Roebroek

doi:10.1371/journal.pone.0038330

Impaired LDL receptor-related protein 1 translocation correlates with improved dyslipidemia and atherosclerosis in apoE-deficient mice.

Philip L S M Gordts
Alexander Bartelt
Stefan K Nilsson
Wim Annaert
Christina Christoffersen
Lars Bo Nielsen
Jörg Heeren
Anton J M Roebroek

Related Research units

Department of Biochemistry and Molecular Cell Biology

Abstract

Determination of the in vivo significance of LDL receptor-related protein 1 (LRP1) dysfunction on lipid metabolism and atherosclerosis development in absence of its main ligand apoE.

Bibliographical data

Original language	English
Article number	6
ISSN	1932-6203
DOIs	https://doi.org/10.1371/journal.pone.0038330
Publication status	Published - 2012

pubmed	22701627