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Impact of TBX21, GATA3, and FOXP3 gene polymorphisms on acute cellular rejection after liver transplantation

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Impact of TBX21, GATA3, and FOXP3 gene polymorphisms on acute cellular rejection after liver transplantation. / Thude, Hansjörg; Tiede, Petra; Sterneck, Martina; Nashan, Björn; Koch, Martina.

In: HLA, Vol. 93, No. 2-3, 02.2019, p. 97-101.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research

Harvard

Thude, H, Tiede, P, Sterneck, M, Nashan, B & Koch, M 2019, 'Impact of TBX21, GATA3, and FOXP3 gene polymorphisms on acute cellular rejection after liver transplantation', HLA, vol. 93, no. 2-3, pp. 97-101. https://doi.org/10.1111/tan.13458

APA

Thude, H., Tiede, P., Sterneck, M., Nashan, B., & Koch, M. (2019). Impact of TBX21, GATA3, and FOXP3 gene polymorphisms on acute cellular rejection after liver transplantation. HLA, 93(2-3), 97-101. https://doi.org/10.1111/tan.13458

Vancouver

Thude H, Tiede P, Sterneck M, Nashan B, Koch M. Impact of TBX21, GATA3, and FOXP3 gene polymorphisms on acute cellular rejection after liver transplantation. HLA. 2019 Feb;93(2-3):97-101. https://doi.org/10.1111/tan.13458

Bibtex

@article{206efd466c954cb59c20bbded99403b1,
title = "Impact of TBX21, GATA3, and FOXP3 gene polymorphisms on acute cellular rejection after liver transplantation",
abstract = "The single nucleotide polymorphisms (SNPs) rs4794067, rs2275806, rs2232365, and rs3761548 map in the genes of TBX21, GATA3, and FOXP3 involved in mediating acute cellular rejection. We investigated whether these SNPs are associated with acute cellular liver transplant rejection. The SNPs were analyzed in recipients with early acute cellular rejection (n = 97), recipients with late acute cellular rejection (n = 49), and recipients without rejection (n = 149). There was no association between acute cellular rejection and SNPs rs4794067, rs2275806, and rs2232365. In contrast, the allele -3279A of FOXP3 SNP rs3761548 exhibited a higher frequency in recipients with late acute cellular rejection as compared with recipients without rejection. This result indicates that the allele -3279A of the SNP rs3761548 may predispose to the development of late acute cellular rejection.",
author = "Hansj{\"o}rg Thude and Petra Tiede and Martina Sterneck and Bj{\"o}rn Nashan and Martina Koch",
note = "{\textcopyright} 2019 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.",
year = "2019",
month = feb,
doi = "10.1111/tan.13458",
language = "English",
volume = "93",
pages = "97--101",
journal = "HLA",
issn = "2059-2302",
publisher = "Wiley-Blackwell",
number = "2-3",

}

RIS

TY - JOUR

T1 - Impact of TBX21, GATA3, and FOXP3 gene polymorphisms on acute cellular rejection after liver transplantation

AU - Thude, Hansjörg

AU - Tiede, Petra

AU - Sterneck, Martina

AU - Nashan, Björn

AU - Koch, Martina

N1 - © 2019 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

PY - 2019/2

Y1 - 2019/2

N2 - The single nucleotide polymorphisms (SNPs) rs4794067, rs2275806, rs2232365, and rs3761548 map in the genes of TBX21, GATA3, and FOXP3 involved in mediating acute cellular rejection. We investigated whether these SNPs are associated with acute cellular liver transplant rejection. The SNPs were analyzed in recipients with early acute cellular rejection (n = 97), recipients with late acute cellular rejection (n = 49), and recipients without rejection (n = 149). There was no association between acute cellular rejection and SNPs rs4794067, rs2275806, and rs2232365. In contrast, the allele -3279A of FOXP3 SNP rs3761548 exhibited a higher frequency in recipients with late acute cellular rejection as compared with recipients without rejection. This result indicates that the allele -3279A of the SNP rs3761548 may predispose to the development of late acute cellular rejection.

AB - The single nucleotide polymorphisms (SNPs) rs4794067, rs2275806, rs2232365, and rs3761548 map in the genes of TBX21, GATA3, and FOXP3 involved in mediating acute cellular rejection. We investigated whether these SNPs are associated with acute cellular liver transplant rejection. The SNPs were analyzed in recipients with early acute cellular rejection (n = 97), recipients with late acute cellular rejection (n = 49), and recipients without rejection (n = 149). There was no association between acute cellular rejection and SNPs rs4794067, rs2275806, and rs2232365. In contrast, the allele -3279A of FOXP3 SNP rs3761548 exhibited a higher frequency in recipients with late acute cellular rejection as compared with recipients without rejection. This result indicates that the allele -3279A of the SNP rs3761548 may predispose to the development of late acute cellular rejection.

U2 - 10.1111/tan.13458

DO - 10.1111/tan.13458

M3 - SCORING: Journal article

C2 - 30614205

VL - 93

SP - 97

EP - 101

JO - HLA

JF - HLA

SN - 2059-2302

IS - 2-3

ER -