Impact of obesity on acute complications of catheter ablation for cardiac arrhythmia
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Impact of obesity on acute complications of catheter ablation for cardiac arrhythmia. / Schenker, Niklas; von Blumenthal, Flurina; Hakmi, Samer; Lemes, Christine; Mathew, Shibu; Rottner, Laura; Wohlmuth, Peter; Reißmann, Bruno; Rillig, Andreas; Metzner, Andreas; Willems, Stephan; Ouyang, Feifan; Kuck, Karl-Heinz; Maurer, Tilman.
In: J CARDIOVASC ELECTR, Vol. 33, No. 4, 04.2022, p. 654-663.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
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TY - JOUR
T1 - Impact of obesity on acute complications of catheter ablation for cardiac arrhythmia
AU - Schenker, Niklas
AU - von Blumenthal, Flurina
AU - Hakmi, Samer
AU - Lemes, Christine
AU - Mathew, Shibu
AU - Rottner, Laura
AU - Wohlmuth, Peter
AU - Reißmann, Bruno
AU - Rillig, Andreas
AU - Metzner, Andreas
AU - Willems, Stephan
AU - Ouyang, Feifan
AU - Kuck, Karl-Heinz
AU - Maurer, Tilman
N1 - © 2022 Wiley Periodicals LLC.
PY - 2022/4
Y1 - 2022/4
N2 - INTRODUCTION: The prevalence of obesity is increasing. However, data on the periprocedural complication rate of catheter ablation for arrhythmia in patients stratified by body mass index (BMI) are scarce.METHODS: This study included 1000 consecutive patients (age 62.0 ± 14.4 years) undergoing catheter ablation for cardiac arrhythmia. The primary study endpoint was any periprocedural major complication (cardiac tamponade, pseudoaneurysm, arteriovenous fistula, transient ischemic attack, stroke, valve damage, myocardial infarction, or death).RESULTS: The mean BMI was 27.6 ± 5.1 kg/m2 and the majority of patients were overweight (BMI 25.0-29.9 kg/m2 , 43.4%). A BMI of 30.0-34.9 kg/m2 (Class I obesity) was present in 177 (17.7%) of patients, a BMI of 35.0-39.9 kg/m2 (Class II obesity) in 67 (6.7%), and a BMI ≥ 40 kg/m2 (Class III obesity) in 16 (1.6%). There were 31 major complications (3.1%) and one fatality (0.1%) due to terminal heart failure in a patient undergoing palliative ventricular tachycardia ablation. There was no significant impact of the BMI on the rate of major complications (p = .495). Compared to normal weight patients, odds ratios for complications in overweight patients, as well as Class I, II, and III obesity were 1.1 (95% confidence interval (CI): 0.8, 1.7), 1.3 (CI: 0.6, 2.6), 1.4 (CI: 0.5, 4.1), and 1.6 (CI: 0.4, 6.3), respectively. Radiation exposure and procedure duration were significantly increased in obese patients (p < .001 and p = .001, respectively).CONCLUSION: In this study, obesity did not have a significant impact on the incidence of periprocedural complications after CA for cardiac arrhythmia.
AB - INTRODUCTION: The prevalence of obesity is increasing. However, data on the periprocedural complication rate of catheter ablation for arrhythmia in patients stratified by body mass index (BMI) are scarce.METHODS: This study included 1000 consecutive patients (age 62.0 ± 14.4 years) undergoing catheter ablation for cardiac arrhythmia. The primary study endpoint was any periprocedural major complication (cardiac tamponade, pseudoaneurysm, arteriovenous fistula, transient ischemic attack, stroke, valve damage, myocardial infarction, or death).RESULTS: The mean BMI was 27.6 ± 5.1 kg/m2 and the majority of patients were overweight (BMI 25.0-29.9 kg/m2 , 43.4%). A BMI of 30.0-34.9 kg/m2 (Class I obesity) was present in 177 (17.7%) of patients, a BMI of 35.0-39.9 kg/m2 (Class II obesity) in 67 (6.7%), and a BMI ≥ 40 kg/m2 (Class III obesity) in 16 (1.6%). There were 31 major complications (3.1%) and one fatality (0.1%) due to terminal heart failure in a patient undergoing palliative ventricular tachycardia ablation. There was no significant impact of the BMI on the rate of major complications (p = .495). Compared to normal weight patients, odds ratios for complications in overweight patients, as well as Class I, II, and III obesity were 1.1 (95% confidence interval (CI): 0.8, 1.7), 1.3 (CI: 0.6, 2.6), 1.4 (CI: 0.5, 4.1), and 1.6 (CI: 0.4, 6.3), respectively. Radiation exposure and procedure duration were significantly increased in obese patients (p < .001 and p = .001, respectively).CONCLUSION: In this study, obesity did not have a significant impact on the incidence of periprocedural complications after CA for cardiac arrhythmia.
KW - Aged
KW - Atrial Fibrillation
KW - Body Mass Index
KW - Catheter Ablation/adverse effects
KW - Humans
KW - Middle Aged
KW - Obesity/complications
KW - Overweight/complications
KW - Risk Factors
U2 - 10.1111/jce.15400
DO - 10.1111/jce.15400
M3 - SCORING: Journal article
C2 - 35118743
VL - 33
SP - 654
EP - 663
JO - J CARDIOVASC ELECTR
JF - J CARDIOVASC ELECTR
SN - 1045-3873
IS - 4
ER -
