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Impact of large-volume thoracentesis on transpulmonary thermodilution-derived extravascular lung water in medical intensive care unit patients

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Impact of large-volume thoracentesis on transpulmonary thermodilution-derived extravascular lung water in medical intensive care unit patients. / Saugel, Bernd; Phillip, Veit; Ernesti, Christina; Messer, Marlena; Meidert, Agnes S; Schmid, Roland M; Huber, Wolfgang.

In: J CRIT CARE, Vol. 28, No. 2, 01.04.2013, p. 196-201.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Saugel, B, Phillip, V, Ernesti, C, Messer, M, Meidert, AS, Schmid, RM & Huber, W 2013, 'Impact of large-volume thoracentesis on transpulmonary thermodilution-derived extravascular lung water in medical intensive care unit patients', J CRIT CARE, vol. 28, no. 2, pp. 196-201. https://doi.org/10.1016/j.jcrc.2012.05.002

APA

Saugel, B., Phillip, V., Ernesti, C., Messer, M., Meidert, A. S., Schmid, R. M., & Huber, W. (2013). Impact of large-volume thoracentesis on transpulmonary thermodilution-derived extravascular lung water in medical intensive care unit patients. J CRIT CARE, 28(2), 196-201. https://doi.org/10.1016/j.jcrc.2012.05.002

Vancouver

Saugel B, Phillip V, Ernesti C, Messer M, Meidert AS, Schmid RM et al. Impact of large-volume thoracentesis on transpulmonary thermodilution-derived extravascular lung water in medical intensive care unit patients. J CRIT CARE. 2013 Apr 1;28(2):196-201. https://doi.org/10.1016/j.jcrc.2012.05.002

Bibtex

@article{43cae9ee8fa1405ba04e4bdf317b89fb,
title = "Impact of large-volume thoracentesis on transpulmonary thermodilution-derived extravascular lung water in medical intensive care unit patients",
abstract = "PURPOSE: The purpose of this study was to investigate the impact of large-volume thoracentesis (>1000 mL) on transpulmonary thermodilution (TPTD)-derived cardiopulmonary parameters with special regard to extravascular lung water index (EVLWI).MATERIALS AND METHODS: Retrospective analysis of a prospectively maintained database including TPTD measurements of patients treated in a medical intensive care unit of a German university hospital between January 2009 and September 2010. Data of 17 patients treated with large-volume thoracentesis were analyzed.RESULTS: A median of 1350 (25%-75% interquartile range [IQR], 1200-1590) mL of pleural fluid was removed. Extravascular lung water index was statistically significantly higher after thoracentesis compared with baseline (9.0 [IQR, 8.0-13.0] vs 8.0 [IQR, 7.0-13.0] mL/kg) (P = .039). Pulmonary vascular permeability index (PVPI) also increased significantly after thoracentesis (1.7 [IQR, 1.3-2.4] vs 1.4 [IQR, 1.1-2.1]) (P = .019). When determined 2 and 6 hours after thoracentesis, EVLWI and PVPI even further increased. Six hours after removal of pleural fluid, we observed a median EVLWI of 11.0 (IQR, 8.0-15.0) mL/kg (P = .048 compared with baseline) and a median PVPI of 2.0 (IQR, 1.5-2.7) (P = .040 compared with baseline).CONCLUSIONS: Large-volume thoracentesis results in a statistically significant increase in TPTD-derived EVLWI. Because EVLWI was higher after removal of pleural fluid, we conclude that pleural effusions do not take part in single-indicator TPTD as a part of the pulmonary thermovolume and do not increase TPTD-derived EVLWI.",
keywords = "Aged, Extravascular Lung Water, Female, Hemodynamics, Hospitals, University, Humans, Intensive Care Units, Male, Middle Aged, Pleural Effusion, Pulmonary Circulation, Retrospective Studies, Thermodilution",
author = "Bernd Saugel and Veit Phillip and Christina Ernesti and Marlena Messer and Meidert, {Agnes S} and Schmid, {Roland M} and Wolfgang Huber",
note = "Copyright {\textcopyright} 2013 Elsevier Inc. All rights reserved.",
year = "2013",
month = apr,
day = "1",
doi = "10.1016/j.jcrc.2012.05.002",
language = "English",
volume = "28",
pages = "196--201",
journal = "J CRIT CARE",
issn = "0883-9441",
publisher = "Elsevier BV",
number = "2",

}

RIS

TY - JOUR

T1 - Impact of large-volume thoracentesis on transpulmonary thermodilution-derived extravascular lung water in medical intensive care unit patients

AU - Saugel, Bernd

AU - Phillip, Veit

AU - Ernesti, Christina

AU - Messer, Marlena

AU - Meidert, Agnes S

AU - Schmid, Roland M

AU - Huber, Wolfgang

N1 - Copyright © 2013 Elsevier Inc. All rights reserved.

PY - 2013/4/1

Y1 - 2013/4/1

N2 - PURPOSE: The purpose of this study was to investigate the impact of large-volume thoracentesis (>1000 mL) on transpulmonary thermodilution (TPTD)-derived cardiopulmonary parameters with special regard to extravascular lung water index (EVLWI).MATERIALS AND METHODS: Retrospective analysis of a prospectively maintained database including TPTD measurements of patients treated in a medical intensive care unit of a German university hospital between January 2009 and September 2010. Data of 17 patients treated with large-volume thoracentesis were analyzed.RESULTS: A median of 1350 (25%-75% interquartile range [IQR], 1200-1590) mL of pleural fluid was removed. Extravascular lung water index was statistically significantly higher after thoracentesis compared with baseline (9.0 [IQR, 8.0-13.0] vs 8.0 [IQR, 7.0-13.0] mL/kg) (P = .039). Pulmonary vascular permeability index (PVPI) also increased significantly after thoracentesis (1.7 [IQR, 1.3-2.4] vs 1.4 [IQR, 1.1-2.1]) (P = .019). When determined 2 and 6 hours after thoracentesis, EVLWI and PVPI even further increased. Six hours after removal of pleural fluid, we observed a median EVLWI of 11.0 (IQR, 8.0-15.0) mL/kg (P = .048 compared with baseline) and a median PVPI of 2.0 (IQR, 1.5-2.7) (P = .040 compared with baseline).CONCLUSIONS: Large-volume thoracentesis results in a statistically significant increase in TPTD-derived EVLWI. Because EVLWI was higher after removal of pleural fluid, we conclude that pleural effusions do not take part in single-indicator TPTD as a part of the pulmonary thermovolume and do not increase TPTD-derived EVLWI.

AB - PURPOSE: The purpose of this study was to investigate the impact of large-volume thoracentesis (>1000 mL) on transpulmonary thermodilution (TPTD)-derived cardiopulmonary parameters with special regard to extravascular lung water index (EVLWI).MATERIALS AND METHODS: Retrospective analysis of a prospectively maintained database including TPTD measurements of patients treated in a medical intensive care unit of a German university hospital between January 2009 and September 2010. Data of 17 patients treated with large-volume thoracentesis were analyzed.RESULTS: A median of 1350 (25%-75% interquartile range [IQR], 1200-1590) mL of pleural fluid was removed. Extravascular lung water index was statistically significantly higher after thoracentesis compared with baseline (9.0 [IQR, 8.0-13.0] vs 8.0 [IQR, 7.0-13.0] mL/kg) (P = .039). Pulmonary vascular permeability index (PVPI) also increased significantly after thoracentesis (1.7 [IQR, 1.3-2.4] vs 1.4 [IQR, 1.1-2.1]) (P = .019). When determined 2 and 6 hours after thoracentesis, EVLWI and PVPI even further increased. Six hours after removal of pleural fluid, we observed a median EVLWI of 11.0 (IQR, 8.0-15.0) mL/kg (P = .048 compared with baseline) and a median PVPI of 2.0 (IQR, 1.5-2.7) (P = .040 compared with baseline).CONCLUSIONS: Large-volume thoracentesis results in a statistically significant increase in TPTD-derived EVLWI. Because EVLWI was higher after removal of pleural fluid, we conclude that pleural effusions do not take part in single-indicator TPTD as a part of the pulmonary thermovolume and do not increase TPTD-derived EVLWI.

KW - Aged

KW - Extravascular Lung Water

KW - Female

KW - Hemodynamics

KW - Hospitals, University

KW - Humans

KW - Intensive Care Units

KW - Male

KW - Middle Aged

KW - Pleural Effusion

KW - Pulmonary Circulation

KW - Retrospective Studies

KW - Thermodilution

U2 - 10.1016/j.jcrc.2012.05.002

DO - 10.1016/j.jcrc.2012.05.002

M3 - SCORING: Journal article

C2 - 22765875

VL - 28

SP - 196

EP - 201

JO - J CRIT CARE

JF - J CRIT CARE

SN - 0883-9441

IS - 2

ER -