Impact of childhood trauma on hypothalamus-pituitary-adrenal axis activity in alcohol-dependent patients.

Abstract

Studies in animals and humans suggest that early life stress alters hypothalamus-pituitary-adrenal (HPA) axis activity. The same alterations are related to the symptoms and course of alcohol dependence. This study examined relationships between childhood trauma and HPA axis activity in alcohol-dependent patients controlling for psychopathology and characteristics of dependence.

Bibliographical data

Original languageGerman
Article number2
ISSN1022-6877
Publication statusPublished - 2010
pubmed 20224278