Immunocytochemical detection and characterisation of individual micrometastatic tumour cells.
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Immunocytochemical detection and characterisation of individual micrometastatic tumour cells. / Braun, Stephan; Pantel, Klaus.
In: Methods Mol Biol, Vol. 878, 2012, p. 63-70.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
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TY - JOUR
T1 - Immunocytochemical detection and characterisation of individual micrometastatic tumour cells.
AU - Braun, Stephan
AU - Pantel, Klaus
PY - 2012
Y1 - 2012
N2 - Detection of micrometastases in the bone marrow (BM) of cancer patients may be a helpful method for early detection of relapse. The diverse methodology employed across different laboratories, however, renders comparison of results difficult. This chapter describes a robust reliable system for the immunochemical detection of individual micrometastatic tumour cells from the BM aspirates of patients with solid epithelial tumours, based on the binding of antibody to cytokeratin proteins.
AB - Detection of micrometastases in the bone marrow (BM) of cancer patients may be a helpful method for early detection of relapse. The diverse methodology employed across different laboratories, however, renders comparison of results difficult. This chapter describes a robust reliable system for the immunochemical detection of individual micrometastatic tumour cells from the BM aspirates of patients with solid epithelial tumours, based on the binding of antibody to cytokeratin proteins.
KW - Humans
KW - Staining and Labeling
KW - Bone Marrow Neoplasms/pathology
KW - Immunohistochemistry/methods
KW - Neoplasm Micrometastasis/diagnosis/pathology
KW - Humans
KW - Staining and Labeling
KW - Bone Marrow Neoplasms/pathology
KW - Immunohistochemistry/methods
KW - Neoplasm Micrometastasis/diagnosis/pathology
M3 - SCORING: Journal article
VL - 878
SP - 63
EP - 70
JO - Methods Mol Biol
JF - Methods Mol Biol
SN - 1064-3745
ER -