Immune regulation in renal inflammation

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Immune regulation in renal inflammation. / Neumann, Katrin; Tiegs, Gisa.

In: CELL TISSUE RES, Vol. 385, No. 2, 08.2021, p. 305-322.

Research output: SCORING: Contribution to journalSCORING: Review articleResearch

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@article{5238437c4a064f7a8eddc0c2269851f8,
title = "Immune regulation in renal inflammation",
abstract = "Renal inflammation, induced by autoantigen recognition or toxic drugs, leads to renal tissue injury and decline in kidney function. Recent studies have demonstrated the crucial role for regulatory T cells in suppressing pathogenic adaptive but also innate immune responses in the inflamed kidney. However, there is also evidence for other immune cell populations with immunosuppressive function in renal inflammation. This review summarizes mechanisms of immune cell regulation in immune-mediated glomerulonephritis and acute and chronic nephrotoxicity.",
author = "Katrin Neumann and Gisa Tiegs",
year = "2021",
month = aug,
doi = "10.1007/s00441-020-03351-1",
language = "English",
volume = "385",
pages = "305--322",
journal = "CELL TISSUE RES",
issn = "0302-766X",
publisher = "Springer",
number = "2",

}

RIS

TY - JOUR

T1 - Immune regulation in renal inflammation

AU - Neumann, Katrin

AU - Tiegs, Gisa

PY - 2021/8

Y1 - 2021/8

N2 - Renal inflammation, induced by autoantigen recognition or toxic drugs, leads to renal tissue injury and decline in kidney function. Recent studies have demonstrated the crucial role for regulatory T cells in suppressing pathogenic adaptive but also innate immune responses in the inflamed kidney. However, there is also evidence for other immune cell populations with immunosuppressive function in renal inflammation. This review summarizes mechanisms of immune cell regulation in immune-mediated glomerulonephritis and acute and chronic nephrotoxicity.

AB - Renal inflammation, induced by autoantigen recognition or toxic drugs, leads to renal tissue injury and decline in kidney function. Recent studies have demonstrated the crucial role for regulatory T cells in suppressing pathogenic adaptive but also innate immune responses in the inflamed kidney. However, there is also evidence for other immune cell populations with immunosuppressive function in renal inflammation. This review summarizes mechanisms of immune cell regulation in immune-mediated glomerulonephritis and acute and chronic nephrotoxicity.

U2 - 10.1007/s00441-020-03351-1

DO - 10.1007/s00441-020-03351-1

M3 - SCORING: Review article

C2 - 33496881

VL - 385

SP - 305

EP - 322

JO - CELL TISSUE RES

JF - CELL TISSUE RES

SN - 0302-766X

IS - 2

ER -