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Imitation in patients with Gilles de la Tourette syndrome--a behavioral study.

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Imitation in patients with Gilles de la Tourette syndrome--a behavioral study. / Jonas, Melanie; Thomalla, Götz; Biermann-Ruben, Katja; Siebner, Hartwig Roman; Müller-Vahl, Kirsten; Bäumer, Tobias; Gerloff, Christian; Schnitzler, Alfons; Orth, Michael; Münchau, Alexander.

In: MOVEMENT DISORD, Vol. 25, No. 8, 8, 2010, p. 991-999.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Jonas, M, Thomalla, G, Biermann-Ruben, K, Siebner, HR, Müller-Vahl, K, Bäumer, T, Gerloff, C, Schnitzler, A, Orth, M & Münchau, A 2010, 'Imitation in patients with Gilles de la Tourette syndrome--a behavioral study.', MOVEMENT DISORD, vol. 25, no. 8, 8, pp. 991-999.

APA

Jonas, M., Thomalla, G., Biermann-Ruben, K., Siebner, H. R., Müller-Vahl, K., Bäumer, T., Gerloff, C., Schnitzler, A., Orth, M., & Münchau, A. (2010). Imitation in patients with Gilles de la Tourette syndrome--a behavioral study. MOVEMENT DISORD, 25(8), 991-999. [8].

Vancouver

Jonas M, Thomalla G, Biermann-Ruben K, Siebner HR, Müller-Vahl K, Bäumer T et al. Imitation in patients with Gilles de la Tourette syndrome--a behavioral study. MOVEMENT DISORD. 2010;25(8):991-999. 8.

Bibtex

@article{d3f24170c5df4730946ad17acf491ec9,
title = "Imitation in patients with Gilles de la Tourette syndrome--a behavioral study.",
abstract = "Echophenomena in Gilles de la Tourette syndrome (GTS) may relate to deficient processing of observed biological movements. This would be reflected in altered effects of movement observation on motor responses in these patients. We studied reaction times in 11 unmedicated GTS patients without psychiatric comorbidity and healthy subjects. In experiment 1, participants imitated single biological finger movement stimuli or nonbiological dot movement stimuli immediately. In experiment 2, participants responded to a tone while viewing biological or nonbiological movement stimuli that were either compatible (identical) or incompatible (different) with their response. In experiment 1, both patients and healthy subjects responded faster to single biological than to nonbiological stimuli. In experiment 2, biological stimuli caused a larger compatibility-effect in responses than nonbiological stimuli in both groups, provided stimulus presentation and response initiation coincided. Healthy subjects responded faster to compatible biological than nonbiological stimuli. In contrast, GTS patients responded slower to incompatible biological than nonbiological stimuli. Patients' mean reaction time in experiment 2 correlated with phonic tic-frequency. Motor facilitation by observing biological movements appears to rely on concomitance of stimuli and responses in GTS patients and healthy individuals. Differing behavioral effects of movement observation in GTS might reflect altered activation of an action observation-execution matching system. To avoid unwanted movements GTS patients probably have to inhibit motor activation induced by observed movement automatically. Thus, movement stimuli may facilitate similar motor responses less but interfere more with different responses in these patients.",
author = "Melanie Jonas and G{\"o}tz Thomalla and Katja Biermann-Ruben and Siebner, {Hartwig Roman} and Kirsten M{\"u}ller-Vahl and Tobias B{\"a}umer and Christian Gerloff and Alfons Schnitzler and Michael Orth and Alexander M{\"u}nchau",
year = "2010",
language = "English",
volume = "25",
pages = "991--999",
journal = "MOVEMENT DISORD",
issn = "0885-3185",
publisher = "John Wiley and Sons Inc.",
number = "8",

}

RIS

TY - JOUR

T1 - Imitation in patients with Gilles de la Tourette syndrome--a behavioral study.

AU - Jonas, Melanie

AU - Thomalla, Götz

AU - Biermann-Ruben, Katja

AU - Siebner, Hartwig Roman

AU - Müller-Vahl, Kirsten

AU - Bäumer, Tobias

AU - Gerloff, Christian

AU - Schnitzler, Alfons

AU - Orth, Michael

AU - Münchau, Alexander

PY - 2010

Y1 - 2010

N2 - Echophenomena in Gilles de la Tourette syndrome (GTS) may relate to deficient processing of observed biological movements. This would be reflected in altered effects of movement observation on motor responses in these patients. We studied reaction times in 11 unmedicated GTS patients without psychiatric comorbidity and healthy subjects. In experiment 1, participants imitated single biological finger movement stimuli or nonbiological dot movement stimuli immediately. In experiment 2, participants responded to a tone while viewing biological or nonbiological movement stimuli that were either compatible (identical) or incompatible (different) with their response. In experiment 1, both patients and healthy subjects responded faster to single biological than to nonbiological stimuli. In experiment 2, biological stimuli caused a larger compatibility-effect in responses than nonbiological stimuli in both groups, provided stimulus presentation and response initiation coincided. Healthy subjects responded faster to compatible biological than nonbiological stimuli. In contrast, GTS patients responded slower to incompatible biological than nonbiological stimuli. Patients' mean reaction time in experiment 2 correlated with phonic tic-frequency. Motor facilitation by observing biological movements appears to rely on concomitance of stimuli and responses in GTS patients and healthy individuals. Differing behavioral effects of movement observation in GTS might reflect altered activation of an action observation-execution matching system. To avoid unwanted movements GTS patients probably have to inhibit motor activation induced by observed movement automatically. Thus, movement stimuli may facilitate similar motor responses less but interfere more with different responses in these patients.

AB - Echophenomena in Gilles de la Tourette syndrome (GTS) may relate to deficient processing of observed biological movements. This would be reflected in altered effects of movement observation on motor responses in these patients. We studied reaction times in 11 unmedicated GTS patients without psychiatric comorbidity and healthy subjects. In experiment 1, participants imitated single biological finger movement stimuli or nonbiological dot movement stimuli immediately. In experiment 2, participants responded to a tone while viewing biological or nonbiological movement stimuli that were either compatible (identical) or incompatible (different) with their response. In experiment 1, both patients and healthy subjects responded faster to single biological than to nonbiological stimuli. In experiment 2, biological stimuli caused a larger compatibility-effect in responses than nonbiological stimuli in both groups, provided stimulus presentation and response initiation coincided. Healthy subjects responded faster to compatible biological than nonbiological stimuli. In contrast, GTS patients responded slower to incompatible biological than nonbiological stimuli. Patients' mean reaction time in experiment 2 correlated with phonic tic-frequency. Motor facilitation by observing biological movements appears to rely on concomitance of stimuli and responses in GTS patients and healthy individuals. Differing behavioral effects of movement observation in GTS might reflect altered activation of an action observation-execution matching system. To avoid unwanted movements GTS patients probably have to inhibit motor activation induced by observed movement automatically. Thus, movement stimuli may facilitate similar motor responses less but interfere more with different responses in these patients.

M3 - SCORING: Journal article

VL - 25

SP - 991

EP - 999

JO - MOVEMENT DISORD

JF - MOVEMENT DISORD

SN - 0885-3185

IS - 8

M1 - 8

ER -