Hypertrophic olivary degeneration with gadolinium enhancement after posterior fossa surgery in a child with medulloblastoma

Standard

Hypertrophic olivary degeneration with gadolinium enhancement after posterior fossa surgery in a child with medulloblastoma. / Nowak, Johannes; Alkonyi, Balint; Rutkowski, Stefan; Homola, György A; Warmuth-Metz, Monika.

In: CHILD NERV SYST, Vol. 30, No. 5, 01.05.2014, p. 959-62.

Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

Harvard

APA

Vancouver

Bibtex

@article{2bf4b6a611124581bb8bc6f73d228b47,
title = "Hypertrophic olivary degeneration with gadolinium enhancement after posterior fossa surgery in a child with medulloblastoma",
abstract = "Hypertrophic olivary degeneration (HOD) is a rare transsynaptic form of degeneration occurring secondary to the disruption of the dentato-rubro-olivary pathway ({"}Guillain-Mollaret triangle{"}). HOD can be caused by ischemic, hemorrhagic, traumatic, or neoplastic lesions, and it can also occur following posterior fossa surgery. MRI characteristics of HOD include T2 signal increase and hypertrophy. To date, blood–brain barrier disruption has not been reported in HOD. Here, we present the first case of HOD with temporary gadolinium enhancement in a 10-year-old child 7 months after resection of a posterior fossa medulloblastoma. The recognition of gadolinium enhancement as a radiological feature of HOD may help to distinguish between this benign secondary condition and tumor recurrence.",
author = "Johannes Nowak and Balint Alkonyi and Stefan Rutkowski and Homola, {Gy{\"o}rgy A} and Monika Warmuth-Metz",
year = "2014",
month = may,
day = "1",
doi = "10.1007/s00381-013-2296-0",
language = "English",
volume = "30",
pages = "959--62",
journal = "CHILD NERV SYST",
issn = "0256-7040",
publisher = "Springer",
number = "5",

}

RIS

TY - JOUR

T1 - Hypertrophic olivary degeneration with gadolinium enhancement after posterior fossa surgery in a child with medulloblastoma

AU - Nowak, Johannes

AU - Alkonyi, Balint

AU - Rutkowski, Stefan

AU - Homola, György A

AU - Warmuth-Metz, Monika

PY - 2014/5/1

Y1 - 2014/5/1

N2 - Hypertrophic olivary degeneration (HOD) is a rare transsynaptic form of degeneration occurring secondary to the disruption of the dentato-rubro-olivary pathway ("Guillain-Mollaret triangle"). HOD can be caused by ischemic, hemorrhagic, traumatic, or neoplastic lesions, and it can also occur following posterior fossa surgery. MRI characteristics of HOD include T2 signal increase and hypertrophy. To date, blood–brain barrier disruption has not been reported in HOD. Here, we present the first case of HOD with temporary gadolinium enhancement in a 10-year-old child 7 months after resection of a posterior fossa medulloblastoma. The recognition of gadolinium enhancement as a radiological feature of HOD may help to distinguish between this benign secondary condition and tumor recurrence.

AB - Hypertrophic olivary degeneration (HOD) is a rare transsynaptic form of degeneration occurring secondary to the disruption of the dentato-rubro-olivary pathway ("Guillain-Mollaret triangle"). HOD can be caused by ischemic, hemorrhagic, traumatic, or neoplastic lesions, and it can also occur following posterior fossa surgery. MRI characteristics of HOD include T2 signal increase and hypertrophy. To date, blood–brain barrier disruption has not been reported in HOD. Here, we present the first case of HOD with temporary gadolinium enhancement in a 10-year-old child 7 months after resection of a posterior fossa medulloblastoma. The recognition of gadolinium enhancement as a radiological feature of HOD may help to distinguish between this benign secondary condition and tumor recurrence.

U2 - 10.1007/s00381-013-2296-0

DO - 10.1007/s00381-013-2296-0

M3 - SCORING: Journal article

C2 - 24122017

VL - 30

SP - 959

EP - 962

JO - CHILD NERV SYST

JF - CHILD NERV SYST

SN - 0256-7040

IS - 5

ER -