Hyperfractionation: where do we stand?
Standard
Hyperfractionation: where do we stand? / Beck-Bornholdt, Hans-Peter; Dubben, H H; Liertz-Petersen, C; Willers, H.
In: RADIOTHER ONCOL, Vol. 43, No. 1, 1, 1997, p. 1-21.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Harvard
APA
Vancouver
Bibtex
}
RIS
TY - JOUR
T1 - Hyperfractionation: where do we stand?
AU - Beck-Bornholdt, Hans-Peter
AU - Dubben, H H
AU - Liertz-Petersen, C
AU - Willers, H
PY - 1997
Y1 - 1997
N2 - Hyperfractionation is generally expected to allow an escalation of total dose, thereby increasing tumour control rate, without increasing the risk of late complications. The purpose of this review is to assess the empirical evidence for this therapeutic gain from hyperfractionated radiotherapy. Although extensive clinical data have been accumulated until now, especially on treatment of head and neck cancer, the line of evidence is not consistent. The present analysis indicates that the dose per fraction generally used in standard radiotherapy is already a good choice.
AB - Hyperfractionation is generally expected to allow an escalation of total dose, thereby increasing tumour control rate, without increasing the risk of late complications. The purpose of this review is to assess the empirical evidence for this therapeutic gain from hyperfractionated radiotherapy. Although extensive clinical data have been accumulated until now, especially on treatment of head and neck cancer, the line of evidence is not consistent. The present analysis indicates that the dose per fraction generally used in standard radiotherapy is already a good choice.
M3 - SCORING: Zeitschriftenaufsatz
VL - 43
SP - 1
EP - 21
JO - RADIOTHER ONCOL
JF - RADIOTHER ONCOL
SN - 0167-8140
IS - 1
M1 - 1
ER -