Human kallikrein 8, a novel biomarker for ovarian carcinoma
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Human kallikrein 8, a novel biomarker for ovarian carcinoma. / Kishi, Tadaaki; Grass, Linda; Soosaipillai, Antoninus; Scorilas, Andreas; Harbeck, Nadia; Schmalfeldt, Barbara; Dorn, Julia; Mysliwiec, Michal; Schmitt, Manfred; Diamandis, Eleftherios P.
In: CANCER RES, Vol. 63, No. 11, 01.06.2003, p. 2771-4.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
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TY - JOUR
T1 - Human kallikrein 8, a novel biomarker for ovarian carcinoma
AU - Kishi, Tadaaki
AU - Grass, Linda
AU - Soosaipillai, Antoninus
AU - Scorilas, Andreas
AU - Harbeck, Nadia
AU - Schmalfeldt, Barbara
AU - Dorn, Julia
AU - Mysliwiec, Michal
AU - Schmitt, Manfred
AU - Diamandis, Eleftherios P
PY - 2003/6/1
Y1 - 2003/6/1
N2 - Human kallikrein 8 (hK8; neuropsin) is a serine protease and new member of the hK family. The aim of this study was to examine if hK8 may serve as a novel cancer biomarker. An hk8-ELISA, developed in-house, was used to study the distribution of hK8 in various biological fluids and tissue extracts from healthy individuals and ovarian cancer patients of different stages of the disease (International Federation of Obstetrics and Gynecology II-IV). For ovarian cancer patients, very high levels in ascites fluid were observed (
AB - Human kallikrein 8 (hK8; neuropsin) is a serine protease and new member of the hK family. The aim of this study was to examine if hK8 may serve as a novel cancer biomarker. An hk8-ELISA, developed in-house, was used to study the distribution of hK8 in various biological fluids and tissue extracts from healthy individuals and ovarian cancer patients of different stages of the disease (International Federation of Obstetrics and Gynecology II-IV). For ovarian cancer patients, very high levels in ascites fluid were observed (
KW - Ascitic Fluid
KW - Chromatography, High Pressure Liquid
KW - Cytosol
KW - Female
KW - Humans
KW - Immunoassay
KW - Kallikreins
KW - Neoplasm Staging
KW - Ovarian Neoplasms
KW - Tumor Markers, Biological
M3 - SCORING: Journal article
C2 - 12782581
VL - 63
SP - 2771
EP - 2774
JO - CANCER RES
JF - CANCER RES
SN - 0008-5472
IS - 11
ER -