Homo- and heterotypic cell-cell contacts in Merkel cells and Merkel cell carcinomas: heterogeneity and indications for cadherin switching.

  • Anna M Werling
  • Yvette Doerflinger
  • Johanna Brandner
  • Franca Fuchs
  • Jürgen C Becker
  • David Schrama
  • Hjalmar Kurzen
  • Sergij Goerdt
  • Wiebke K Peitsch

Abstract

Merkel cell carcinomas (MCCs) are rare but aggressive tumours associated recently with Merkel cell polyomavirus (MCV). As development and progression of several types of carcinomas can be promoted by changes in cell adhesion proteins, the aim of this study was to examine homo- and heterotypic cell contacts of Merkel cells and MCCs.

Bibliographical data

Original languageEnglish
Article number2
ISSN0309-0167
Publication statusPublished - 2011
pubmed 21323954