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Hodgkin's lymphoma as a rare variant of Richter's transformation in chronic lymphocytic leukemia: A case report and review of the literature

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Hodgkin's lymphoma as a rare variant of Richter's transformation in chronic lymphocytic leukemia: A case report and review of the literature. / Janjetovic, Snjezana; Bernd, Heinz-Wolfram; Bokemeyer, Carsten; Fiedler, Walter.

In: MOL CLIN ONCOL, Vol. 4, No. 3, 03.2016, p. 390-392.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Janjetovic, S, Bernd, H-W, Bokemeyer, C & Fiedler, W 2016, 'Hodgkin's lymphoma as a rare variant of Richter's transformation in chronic lymphocytic leukemia: A case report and review of the literature', MOL CLIN ONCOL, vol. 4, no. 3, pp. 390-392. https://doi.org/10.3892/mco.2016.727

APA

Janjetovic, S., Bernd, H-W., Bokemeyer, C., & Fiedler, W. (2016). Hodgkin's lymphoma as a rare variant of Richter's transformation in chronic lymphocytic leukemia: A case report and review of the literature. MOL CLIN ONCOL, 4(3), 390-392. https://doi.org/10.3892/mco.2016.727

Vancouver

Janjetovic S, Bernd H-W, Bokemeyer C, Fiedler W. Hodgkin's lymphoma as a rare variant of Richter's transformation in chronic lymphocytic leukemia: A case report and review of the literature. MOL CLIN ONCOL. 2016 Mar;4(3):390-392. https://doi.org/10.3892/mco.2016.727

Bibtex

@article{73239455d6a3458993f235ede379dd5a,
title = "Hodgkin's lymphoma as a rare variant of Richter's transformation in chronic lymphocytic leukemia: A case report and review of the literature",
abstract = "Richter's transformation induces an aggressive clinical course in chronic lymphocytic leukemia (CLL). In the majority of cases, Richter's transformation manifests itself as a high-grade B-cell non-Hodgkin's lymphoma (B-NHL). However, other histological types, such as classical Hodgkin lymphoma (cHL), lymphoblastic lymphoma, hairy cell leukemia and high-grade T-cell NHL have been described previously. The present study reports a rare case of CLL with transformation into classical Hodgkin's lymphoma (cHL). The common clonal origin of CLL and cHL was documented by immunoglobulin gene rearrangement analysis performed using multiplex polymerase chain reaction. Following a review of the literature, treatment of secondary Hodgkin's lymphoma is discussed, and prognosis is often poor.",
author = "Snjezana Janjetovic and Heinz-Wolfram Bernd and Carsten Bokemeyer and Walter Fiedler",
year = "2016",
month = mar,
doi = "10.3892/mco.2016.727",
language = "English",
volume = "4",
pages = "390--392",
journal = "MOL CLIN ONCOL",
issn = "2049-9450",
publisher = "Spandidos Publications",
number = "3",

}

RIS

TY - JOUR

T1 - Hodgkin's lymphoma as a rare variant of Richter's transformation in chronic lymphocytic leukemia: A case report and review of the literature

AU - Janjetovic, Snjezana

AU - Bernd, Heinz-Wolfram

AU - Bokemeyer, Carsten

AU - Fiedler, Walter

PY - 2016/3

Y1 - 2016/3

N2 - Richter's transformation induces an aggressive clinical course in chronic lymphocytic leukemia (CLL). In the majority of cases, Richter's transformation manifests itself as a high-grade B-cell non-Hodgkin's lymphoma (B-NHL). However, other histological types, such as classical Hodgkin lymphoma (cHL), lymphoblastic lymphoma, hairy cell leukemia and high-grade T-cell NHL have been described previously. The present study reports a rare case of CLL with transformation into classical Hodgkin's lymphoma (cHL). The common clonal origin of CLL and cHL was documented by immunoglobulin gene rearrangement analysis performed using multiplex polymerase chain reaction. Following a review of the literature, treatment of secondary Hodgkin's lymphoma is discussed, and prognosis is often poor.

AB - Richter's transformation induces an aggressive clinical course in chronic lymphocytic leukemia (CLL). In the majority of cases, Richter's transformation manifests itself as a high-grade B-cell non-Hodgkin's lymphoma (B-NHL). However, other histological types, such as classical Hodgkin lymphoma (cHL), lymphoblastic lymphoma, hairy cell leukemia and high-grade T-cell NHL have been described previously. The present study reports a rare case of CLL with transformation into classical Hodgkin's lymphoma (cHL). The common clonal origin of CLL and cHL was documented by immunoglobulin gene rearrangement analysis performed using multiplex polymerase chain reaction. Following a review of the literature, treatment of secondary Hodgkin's lymphoma is discussed, and prognosis is often poor.

U2 - 10.3892/mco.2016.727

DO - 10.3892/mco.2016.727

M3 - SCORING: Journal article

C2 - 26998289

VL - 4

SP - 390

EP - 392

JO - MOL CLIN ONCOL

JF - MOL CLIN ONCOL

SN - 2049-9450

IS - 3

ER -