Heme oxygenase-1 germ line GTn promoter polymorphism is an independent prognosticator of tumor recurrence and survival in pancreatic cancer.

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Heme oxygenase-1 germ line GTn promoter polymorphism is an independent prognosticator of tumor recurrence and survival in pancreatic cancer. / Vashist, Yogesh; Uzunoglu, Faik Güntac; Kutup, Asad; Gebauer, Florian; König, Alexandra; Deutsch, Lena; Zehler, Oliver; Busch, Philipp; Kalinin, Vjacheslav; Izbicki, Jakob R.; Yekebas, Emre F.

In: J SURG ONCOL, Vol. 104, No. 3, 3, 2011, p. 305-311.

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@article{2fb1c2267e194bf9bbbcd77357b5bcdd,
title = "Heme oxygenase-1 germ line GTn promoter polymorphism is an independent prognosticator of tumor recurrence and survival in pancreatic cancer.",
abstract = "Heme oxygenase-1 (HO-1) correlates with aggressive tumor behavior and chemotherapy resistance in pancreatic cancer (PC). We evaluated the prognostic value of the basal transcription controlling germ line GTn repeat polymorphism (GTn) in the promoter region of the HO-1 gene in PC.",
keywords = "Humans, Male, Female, Middle Aged, Prospective Studies, Prognosis, Survival Rate, Genotype, Neoplasm Staging, Case-Control Studies, Polymerase Chain Reaction, Promoter Regions, Genetic/*genetics, DNA, Neoplasm/genetics, Adenocarcinoma/genetics/mortality, Germ Cells, Heme Oxygenase-1/*genetics, Neoplasm Recurrence, Local/diagnosis/*genetics/*mortality, Pancreatic Neoplasms/*genetics/*mortality, Polymorphism, Genetic/*genetics, Humans, Male, Female, Middle Aged, Prospective Studies, Prognosis, Survival Rate, Genotype, Neoplasm Staging, Case-Control Studies, Polymerase Chain Reaction, Promoter Regions, Genetic/*genetics, DNA, Neoplasm/genetics, Adenocarcinoma/genetics/mortality, Germ Cells, Heme Oxygenase-1/*genetics, Neoplasm Recurrence, Local/diagnosis/*genetics/*mortality, Pancreatic Neoplasms/*genetics/*mortality, Polymorphism, Genetic/*genetics",
author = "Yogesh Vashist and Uzunoglu, {Faik G{\"u}ntac} and Asad Kutup and Florian Gebauer and Alexandra K{\"o}nig and Lena Deutsch and Oliver Zehler and Philipp Busch and Vjacheslav Kalinin and Izbicki, {Jakob R.} and Yekebas, {Emre F.}",
year = "2011",
language = "English",
volume = "104",
pages = "305--311",
journal = "J SURG ONCOL",
issn = "0022-4790",
publisher = "Wiley-Liss Inc.",
number = "3",

}

RIS

TY - JOUR

T1 - Heme oxygenase-1 germ line GTn promoter polymorphism is an independent prognosticator of tumor recurrence and survival in pancreatic cancer.

AU - Vashist, Yogesh

AU - Uzunoglu, Faik Güntac

AU - Kutup, Asad

AU - Gebauer, Florian

AU - König, Alexandra

AU - Deutsch, Lena

AU - Zehler, Oliver

AU - Busch, Philipp

AU - Kalinin, Vjacheslav

AU - Izbicki, Jakob R.

AU - Yekebas, Emre F.

PY - 2011

Y1 - 2011

N2 - Heme oxygenase-1 (HO-1) correlates with aggressive tumor behavior and chemotherapy resistance in pancreatic cancer (PC). We evaluated the prognostic value of the basal transcription controlling germ line GTn repeat polymorphism (GTn) in the promoter region of the HO-1 gene in PC.

AB - Heme oxygenase-1 (HO-1) correlates with aggressive tumor behavior and chemotherapy resistance in pancreatic cancer (PC). We evaluated the prognostic value of the basal transcription controlling germ line GTn repeat polymorphism (GTn) in the promoter region of the HO-1 gene in PC.

KW - Humans

KW - Male

KW - Female

KW - Middle Aged

KW - Prospective Studies

KW - Prognosis

KW - Survival Rate

KW - Genotype

KW - Neoplasm Staging

KW - Case-Control Studies

KW - Polymerase Chain Reaction

KW - Promoter Regions, Genetic/genetics

KW - DNA, Neoplasm/genetics

KW - Adenocarcinoma/genetics/mortality

KW - Germ Cells

KW - Heme Oxygenase-1/genetics

KW - Neoplasm Recurrence, Local/diagnosis/genetics/mortality

KW - Pancreatic Neoplasms/genetics/mortality

KW - Polymorphism, Genetic/genetics

KW - Humans

KW - Male

KW - Female

KW - Middle Aged

KW - Prospective Studies

KW - Prognosis

KW - Survival Rate

KW - Genotype

KW - Neoplasm Staging

KW - Case-Control Studies

KW - Polymerase Chain Reaction

KW - Promoter Regions, Genetic/genetics

KW - DNA, Neoplasm/genetics

KW - Adenocarcinoma/genetics/mortality

KW - Germ Cells

KW - Heme Oxygenase-1/genetics

KW - Neoplasm Recurrence, Local/diagnosis/genetics/mortality

KW - Pancreatic Neoplasms/genetics/mortality

KW - Polymorphism, Genetic/genetics

M3 - SCORING: Journal article

VL - 104

SP - 305

EP - 311

JO - J SURG ONCOL

JF - J SURG ONCOL

SN - 0022-4790

IS - 3

M1 - 3

ER -