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Heart regeneration

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Heart regeneration. / Breckwoldt, Kaja; Weinberger, Florian; Eschenhagen, Thomas.

In: BBA-MOL CELL RES, Vol. 1863, No. 7 Pt B, 01.07.2016, p. 1749-59.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Breckwoldt, K, Weinberger, F & Eschenhagen, T 2016, 'Heart regeneration', BBA-MOL CELL RES, vol. 1863, no. 7 Pt B, pp. 1749-59. https://doi.org/10.1016/j.bbamcr.2015.11.010

APA

Breckwoldt, K., Weinberger, F., & Eschenhagen, T. (2016). Heart regeneration. BBA-MOL CELL RES, 1863(7 Pt B), 1749-59. https://doi.org/10.1016/j.bbamcr.2015.11.010

Vancouver

Breckwoldt K, Weinberger F, Eschenhagen T. Heart regeneration. BBA-MOL CELL RES. 2016 Jul 1;1863(7 Pt B):1749-59. https://doi.org/10.1016/j.bbamcr.2015.11.010

Bibtex

@article{651daf127e11403b90109f8588caf749,
title = "Heart regeneration",
abstract = "Regenerating an injured heart holds great promise for millions of patients suffering from heart diseases. Since the human heart has very limited regenerative capacity, this is a challenging task. Numerous strategies aiming to improve heart function have been developed. In this review we focus on approaches intending to replace damaged heart muscle by new cardiomyocytes. Different strategies for the production of cardiomyocytes from human embryonic stem cells or human induced pluripotent stem cells, by direct reprogramming and induction of cardiomyocyte proliferation are discussed regarding their therapeutic potential and respective advantages and disadvantages. Furthermore, different methods for the transplantation of pluripotent stem cell-derived cardiomyocytes are described and their clinical perspectives are discussed. This article is part of a Special Issue entitled: Cardiomyocyte Biology: Integration of Develomental and Environmental Cues in the Heart edited by Marcus Schaub and Hughes Abriel.",
author = "Kaja Breckwoldt and Florian Weinberger and Thomas Eschenhagen",
note = "Copyright {\textcopyright} 2015 Elsevier B.V. All rights reserved.",
year = "2016",
month = jul,
day = "1",
doi = "10.1016/j.bbamcr.2015.11.010",
language = "English",
volume = "1863",
pages = "1749--59",
journal = "BBA-MOL CELL RES",
issn = "0167-4889",
publisher = "Elsevier",
number = "7 Pt B",

}

RIS

TY - JOUR

T1 - Heart regeneration

AU - Breckwoldt, Kaja

AU - Weinberger, Florian

AU - Eschenhagen, Thomas

N1 - Copyright © 2015 Elsevier B.V. All rights reserved.

PY - 2016/7/1

Y1 - 2016/7/1

N2 - Regenerating an injured heart holds great promise for millions of patients suffering from heart diseases. Since the human heart has very limited regenerative capacity, this is a challenging task. Numerous strategies aiming to improve heart function have been developed. In this review we focus on approaches intending to replace damaged heart muscle by new cardiomyocytes. Different strategies for the production of cardiomyocytes from human embryonic stem cells or human induced pluripotent stem cells, by direct reprogramming and induction of cardiomyocyte proliferation are discussed regarding their therapeutic potential and respective advantages and disadvantages. Furthermore, different methods for the transplantation of pluripotent stem cell-derived cardiomyocytes are described and their clinical perspectives are discussed. This article is part of a Special Issue entitled: Cardiomyocyte Biology: Integration of Develomental and Environmental Cues in the Heart edited by Marcus Schaub and Hughes Abriel.

AB - Regenerating an injured heart holds great promise for millions of patients suffering from heart diseases. Since the human heart has very limited regenerative capacity, this is a challenging task. Numerous strategies aiming to improve heart function have been developed. In this review we focus on approaches intending to replace damaged heart muscle by new cardiomyocytes. Different strategies for the production of cardiomyocytes from human embryonic stem cells or human induced pluripotent stem cells, by direct reprogramming and induction of cardiomyocyte proliferation are discussed regarding their therapeutic potential and respective advantages and disadvantages. Furthermore, different methods for the transplantation of pluripotent stem cell-derived cardiomyocytes are described and their clinical perspectives are discussed. This article is part of a Special Issue entitled: Cardiomyocyte Biology: Integration of Develomental and Environmental Cues in the Heart edited by Marcus Schaub and Hughes Abriel.

U2 - 10.1016/j.bbamcr.2015.11.010

DO - 10.1016/j.bbamcr.2015.11.010

M3 - SCORING: Journal article

C2 - 26597703

VL - 1863

SP - 1749

EP - 1759

JO - BBA-MOL CELL RES

JF - BBA-MOL CELL RES

SN - 0167-4889

IS - 7 Pt B

ER -