Health-Related Quality of Life and Psychological Aspects of Adults With Hemophilia in Iran
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Health-Related Quality of Life and Psychological Aspects of Adults With Hemophilia in Iran. / Rambod, Masoume; Sharif, Farkhondeh; Molazem, Zahra; Khair, Kate; von Mackensen, Sylvia.
In: CLIN APPL THROMB-HEM, Vol. 24, No. 7, 10.2018, p. 1073-1081.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
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TY - JOUR
T1 - Health-Related Quality of Life and Psychological Aspects of Adults With Hemophilia in Iran
AU - Rambod, Masoume
AU - Sharif, Farkhondeh
AU - Molazem, Zahra
AU - Khair, Kate
AU - von Mackensen, Sylvia
PY - 2018/10
Y1 - 2018/10
N2 - Hemophilia causes bleeding that may affect patients' psychological aspects and quality of life. This study aims to evaluate the impact of psychological aspects and pain on health-related quality of life (HRQoL) in adult patients with hemophilia. This cross-sectional study was conducted on 103 patients with hemophilia. Data were collected using hemophilia-specific quality of life, Depression Anxiety Stress Scales, and pain visual analogue scales. Data were analyzed using correlation coefficients, analysis of covariance, and regression analysis. The results showed that 71.7% of patients with hemophilia experienced pain on the study day. The mean score of HRQoL of patients with hemophilia was 51.09 (standard deviation = 19.37). Moreover, 57.4%, 64.6%, and 44.6% of the patients had mild to severe depression, anxiety, and stress, respectively. In addition, a significant association was observed between HRQoL and depression, anxiety, and severity of pain. In the regression model, 48% of changes in HRQOL were explained by the study variables, with the severity of pain and depression being significant predictors. Therefore, attention should be paid to these aspects to improve patients' quality of life and psychosocial health.
AB - Hemophilia causes bleeding that may affect patients' psychological aspects and quality of life. This study aims to evaluate the impact of psychological aspects and pain on health-related quality of life (HRQoL) in adult patients with hemophilia. This cross-sectional study was conducted on 103 patients with hemophilia. Data were collected using hemophilia-specific quality of life, Depression Anxiety Stress Scales, and pain visual analogue scales. Data were analyzed using correlation coefficients, analysis of covariance, and regression analysis. The results showed that 71.7% of patients with hemophilia experienced pain on the study day. The mean score of HRQoL of patients with hemophilia was 51.09 (standard deviation = 19.37). Moreover, 57.4%, 64.6%, and 44.6% of the patients had mild to severe depression, anxiety, and stress, respectively. In addition, a significant association was observed between HRQoL and depression, anxiety, and severity of pain. In the regression model, 48% of changes in HRQOL were explained by the study variables, with the severity of pain and depression being significant predictors. Therefore, attention should be paid to these aspects to improve patients' quality of life and psychosocial health.
KW - Cross-Sectional Studies
KW - Female
KW - Hemophilia A/pathology
KW - Humans
KW - Iran
KW - Male
KW - Quality of Life/psychology
KW - Surveys and Questionnaires
U2 - 10.1177/1076029618758954
DO - 10.1177/1076029618758954
M3 - SCORING: Journal article
C2 - 29575928
VL - 24
SP - 1073
EP - 1081
JO - CLIN APPL THROMB-HEM
JF - CLIN APPL THROMB-HEM
SN - 1076-0296
IS - 7
ER -
