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Harman and norharman plasma levels in weaned alcoholics

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Harman and norharman plasma levels in weaned alcoholics : correlations with depression and tobacco smoking. / Kiefer, F; Krödel, A; Jahn, H; Wolf, K; Barocka, A.

In: ADDICT BIOL, Vol. 5, No. 4, 01.10.2000, p. 437-41.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Kiefer, F, Krödel, A, Jahn, H, Wolf, K & Barocka, A 2000, 'Harman and norharman plasma levels in weaned alcoholics: correlations with depression and tobacco smoking', ADDICT BIOL, vol. 5, no. 4, pp. 437-41. https://doi.org/10.1111/j.1369-1600.2000.tb00213.x

APA

Kiefer, F., Krödel, A., Jahn, H., Wolf, K., & Barocka, A. (2000). Harman and norharman plasma levels in weaned alcoholics: correlations with depression and tobacco smoking. ADDICT BIOL, 5(4), 437-41. https://doi.org/10.1111/j.1369-1600.2000.tb00213.x

Vancouver

Kiefer F, Krödel A, Jahn H, Wolf K, Barocka A. Harman and norharman plasma levels in weaned alcoholics: correlations with depression and tobacco smoking. ADDICT BIOL. 2000 Oct 1;5(4):437-41. https://doi.org/10.1111/j.1369-1600.2000.tb00213.x

Bibtex

@article{ecaebc088f684dc783694073ff651336,
title = "Harman and norharman plasma levels in weaned alcoholics: correlations with depression and tobacco smoking",
abstract = "Based on the hypothesis that β-carbolines are involved in the pathogenesis of alcohol-related mood disturbance, harman and norharman levels were assayed in the blood plasma of alcoholics and correlated to the Hamilton Depression (HAM-D) scores after 3 and 5 weeks post-admission. Tobacco smoking was co-evaluated since it is known to influence β-carboline levels. After a 3-week period, plasma harman but not norharman was increased in depressed alcoholics and positively related to the HAM-D sum-score (r = 0.47; p < 0.04) and to tobacco smoking (r = 0.56; p < 0.02). Since no correlation between depression and smoking was found, these data could account for the higher incidence of depressive symptoms in withdrawn alcoholics with increased harman levels. The partial correlations support this hypothesis.",
author = "F Kiefer and A Kr{\"o}del and H Jahn and K Wolf and A Barocka",
year = "2000",
month = oct,
day = "1",
doi = "10.1111/j.1369-1600.2000.tb00213.x",
language = "English",
volume = "5",
pages = "437--41",
journal = "ADDICT BIOL",
issn = "1355-6215",
publisher = "Wiley-Blackwell",
number = "4",

}

RIS

TY - JOUR

T1 - Harman and norharman plasma levels in weaned alcoholics

T2 - correlations with depression and tobacco smoking

AU - Kiefer, F

AU - Krödel, A

AU - Jahn, H

AU - Wolf, K

AU - Barocka, A

PY - 2000/10/1

Y1 - 2000/10/1

N2 - Based on the hypothesis that β-carbolines are involved in the pathogenesis of alcohol-related mood disturbance, harman and norharman levels were assayed in the blood plasma of alcoholics and correlated to the Hamilton Depression (HAM-D) scores after 3 and 5 weeks post-admission. Tobacco smoking was co-evaluated since it is known to influence β-carboline levels. After a 3-week period, plasma harman but not norharman was increased in depressed alcoholics and positively related to the HAM-D sum-score (r = 0.47; p < 0.04) and to tobacco smoking (r = 0.56; p < 0.02). Since no correlation between depression and smoking was found, these data could account for the higher incidence of depressive symptoms in withdrawn alcoholics with increased harman levels. The partial correlations support this hypothesis.

AB - Based on the hypothesis that β-carbolines are involved in the pathogenesis of alcohol-related mood disturbance, harman and norharman levels were assayed in the blood plasma of alcoholics and correlated to the Hamilton Depression (HAM-D) scores after 3 and 5 weeks post-admission. Tobacco smoking was co-evaluated since it is known to influence β-carboline levels. After a 3-week period, plasma harman but not norharman was increased in depressed alcoholics and positively related to the HAM-D sum-score (r = 0.47; p < 0.04) and to tobacco smoking (r = 0.56; p < 0.02). Since no correlation between depression and smoking was found, these data could account for the higher incidence of depressive symptoms in withdrawn alcoholics with increased harman levels. The partial correlations support this hypothesis.

U2 - 10.1111/j.1369-1600.2000.tb00213.x

DO - 10.1111/j.1369-1600.2000.tb00213.x

M3 - SCORING: Journal article

C2 - 20575862

VL - 5

SP - 437

EP - 441

JO - ADDICT BIOL

JF - ADDICT BIOL

SN - 1355-6215

IS - 4

ER -