Research ExplorerPublicationsHämatologischer Thoraxschmerz - Fall 3 / 2016

Hämatologischer Thoraxschmerz - Fall 3 / 2016

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Hämatologischer Thoraxschmerz - Fall 3 / 2016. / Haen, Sebastian Peter; Mannal, Rebekka; Steeg, Martin; Seizer, Peter; Rockenstiehl, Michaela; Mackensen-Haen, Susanne; Horger, Marius; Kanz, Lothar; Vogel, Wichard.

In: DEUT MED WOCHENSCHR, Vol. 141, No. 9, 04.2016, p. 634.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Haen, SP, Mannal, R, Steeg, M, Seizer, P, Rockenstiehl, M, Mackensen-Haen, S, Horger, M, Kanz, L & Vogel, W 2016, 'Hämatologischer Thoraxschmerz - Fall 3 / 2016', DEUT MED WOCHENSCHR, vol. 141, no. 9, pp. 634. https://doi.org/10.1055/s-0041-109909

APA

Haen, S. P., Mannal, R., Steeg, M., Seizer, P., Rockenstiehl, M., Mackensen-Haen, S., Horger, M., Kanz, L., & Vogel, W. (2016). Hämatologischer Thoraxschmerz - Fall 3 / 2016. DEUT MED WOCHENSCHR, 141(9), 634. https://doi.org/10.1055/s-0041-109909

Vancouver

Haen SP, Mannal R, Steeg M, Seizer P, Rockenstiehl M, Mackensen-Haen S et al. Hämatologischer Thoraxschmerz - Fall 3 / 2016. DEUT MED WOCHENSCHR. 2016 Apr;141(9):634. https://doi.org/10.1055/s-0041-109909

Bibtex

@article{1fd33b6af9174b41945f0242e188a1cf,
title = "H{\"a}matologischer Thoraxschmerz - Fall 3 / 2016",
abstract = "HISTORY AND ADMISSION FINDINGS: We report the case of a 59-year-old male who was admitted to hospital with acute chest pain. Coronary heart disease was known from the medical history. The patient reported recurrent ostealgia and susceptibility for infection during the last months before admission.INVESTIGATIONS: A 75% stenosis of the circumflex branch was treated with a drug eluting stent. Platelet aggregation was inhibited with acetylsalicylic acid and clopidogrel. Due to persisting ostealgia and inflammatory state, spondylodiscitis was excluded in MRI. However, platelets remained low after successful treatment of the infection.DIAGNOSIS, TREATMENT AND COURSE: Bone marrow biopsy revealed an acute lymphoblastic leukemia with positive detection of the Philadelphia chromosome. After chemotherapy and allogenic hematopoietic cell transplantation the patient remains in remission of his acute lymphoblastic leukemia.CONCLUSIONS: Especially in patients with documented history of coronary heart disease, the differential diagnosis of chest pain can be challenging. In this case, the chest pain was based on a subacute coronary ischemia as well as on proliferation of the acute lymphoblastic leukemia. The management of dual oral anticoagulation was performed with higher transfusion limits for thrombocytes and continuous application of thrombocyte aggregation inhibitors.",
keywords = "Allografts, Bone Marrow Examination, Chemotherapy, Adjuvant, Chest Pain/etiology, Coronary Disease/complications, Diagnosis, Differential, Hematopoietic Stem Cell Transplantation, Humans, Male, Middle Aged, Platelet Aggregation, Platelet Aggregation Inhibitors/therapeutic use, Precursor Cell Lymphoblastic Leukemia-Lymphoma/complications",
author = "Haen, {Sebastian Peter} and Rebekka Mannal and Martin Steeg and Peter Seizer and Michaela Rockenstiehl and Susanne Mackensen-Haen and Marius Horger and Lothar Kanz and Wichard Vogel",
note = "{\textcopyright} Georg Thieme Verlag KG Stuttgart · New York.",
year = "2016",
month = apr,
doi = "10.1055/s-0041-109909",
language = "Deutsch",
volume = "141",
pages = "634",
journal = "DEUT MED WOCHENSCHR",
issn = "0012-0472",
publisher = "Georg Thieme Verlag KG",
number = "9",

}

RIS

TY - JOUR

T1 - Hämatologischer Thoraxschmerz - Fall 3 / 2016

AU - Haen, Sebastian Peter

AU - Mannal, Rebekka

AU - Steeg, Martin

AU - Seizer, Peter

AU - Rockenstiehl, Michaela

AU - Mackensen-Haen, Susanne

AU - Horger, Marius

AU - Kanz, Lothar

AU - Vogel, Wichard

N1 - © Georg Thieme Verlag KG Stuttgart · New York.

PY - 2016/4

Y1 - 2016/4

N2 - HISTORY AND ADMISSION FINDINGS: We report the case of a 59-year-old male who was admitted to hospital with acute chest pain. Coronary heart disease was known from the medical history. The patient reported recurrent ostealgia and susceptibility for infection during the last months before admission.INVESTIGATIONS: A 75% stenosis of the circumflex branch was treated with a drug eluting stent. Platelet aggregation was inhibited with acetylsalicylic acid and clopidogrel. Due to persisting ostealgia and inflammatory state, spondylodiscitis was excluded in MRI. However, platelets remained low after successful treatment of the infection.DIAGNOSIS, TREATMENT AND COURSE: Bone marrow biopsy revealed an acute lymphoblastic leukemia with positive detection of the Philadelphia chromosome. After chemotherapy and allogenic hematopoietic cell transplantation the patient remains in remission of his acute lymphoblastic leukemia.CONCLUSIONS: Especially in patients with documented history of coronary heart disease, the differential diagnosis of chest pain can be challenging. In this case, the chest pain was based on a subacute coronary ischemia as well as on proliferation of the acute lymphoblastic leukemia. The management of dual oral anticoagulation was performed with higher transfusion limits for thrombocytes and continuous application of thrombocyte aggregation inhibitors.

AB - HISTORY AND ADMISSION FINDINGS: We report the case of a 59-year-old male who was admitted to hospital with acute chest pain. Coronary heart disease was known from the medical history. The patient reported recurrent ostealgia and susceptibility for infection during the last months before admission.INVESTIGATIONS: A 75% stenosis of the circumflex branch was treated with a drug eluting stent. Platelet aggregation was inhibited with acetylsalicylic acid and clopidogrel. Due to persisting ostealgia and inflammatory state, spondylodiscitis was excluded in MRI. However, platelets remained low after successful treatment of the infection.DIAGNOSIS, TREATMENT AND COURSE: Bone marrow biopsy revealed an acute lymphoblastic leukemia with positive detection of the Philadelphia chromosome. After chemotherapy and allogenic hematopoietic cell transplantation the patient remains in remission of his acute lymphoblastic leukemia.CONCLUSIONS: Especially in patients with documented history of coronary heart disease, the differential diagnosis of chest pain can be challenging. In this case, the chest pain was based on a subacute coronary ischemia as well as on proliferation of the acute lymphoblastic leukemia. The management of dual oral anticoagulation was performed with higher transfusion limits for thrombocytes and continuous application of thrombocyte aggregation inhibitors.

KW - Allografts

KW - Bone Marrow Examination

KW - Chemotherapy, Adjuvant

KW - Chest Pain/etiology

KW - Coronary Disease/complications

KW - Diagnosis, Differential

KW - Hematopoietic Stem Cell Transplantation

KW - Humans

KW - Male

KW - Middle Aged

KW - Platelet Aggregation

KW - Platelet Aggregation Inhibitors/therapeutic use

KW - Precursor Cell Lymphoblastic Leukemia-Lymphoma/complications

U2 - 10.1055/s-0041-109909

DO - 10.1055/s-0041-109909

M3 - SCORING: Zeitschriftenaufsatz

C2 - 27123729

VL - 141

SP - 634

JO - DEUT MED WOCHENSCHR

JF - DEUT MED WOCHENSCHR

SN - 0012-0472

IS - 9

ER -