Genetic variation at chromosome 1p13.3 affects sortilin mRNA expression, cellular LDL-uptake and serum LDL levels which translates to the risk of coronary artery disease.
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Genetic variation at chromosome 1p13.3 affects sortilin mRNA expression, cellular LDL-uptake and serum LDL levels which translates to the risk of coronary artery disease. / Linsel-Nitschke, Patrick; Heeren, Jörg; Aherrahrou, Zouhair; Bruse, Petra; Gieger, Christian; Illig, Thomas; Prokisch, Holger; Heim, Katharina; Doering, Angela; Peters, Annette; Meitinger, Thomas; Wichmann, H-Erich; Hinney, Anke; Reinehr, Thomas; Roth, Christian; Ortlepp, Jan R; Soufi, Mouhidien; Sattler, Alexander M; Schaefer, Jürgen; Stark, Klaus; Hengstenberg, Christian; Schaefer, Arne; Schreiber, Stefan; Kronenberg, Florian; Samani, Nilesh J; Schunkert, Heribert; Erdmann, Jeanette.
In: ATHEROSCLEROSIS, Vol. 208, No. 1, 1, 2010, p. 183-189.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
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TY - JOUR
T1 - Genetic variation at chromosome 1p13.3 affects sortilin mRNA expression, cellular LDL-uptake and serum LDL levels which translates to the risk of coronary artery disease.
AU - Linsel-Nitschke, Patrick
AU - Heeren, Jörg
AU - Aherrahrou, Zouhair
AU - Bruse, Petra
AU - Gieger, Christian
AU - Illig, Thomas
AU - Prokisch, Holger
AU - Heim, Katharina
AU - Doering, Angela
AU - Peters, Annette
AU - Meitinger, Thomas
AU - Wichmann, H-Erich
AU - Hinney, Anke
AU - Reinehr, Thomas
AU - Roth, Christian
AU - Ortlepp, Jan R
AU - Soufi, Mouhidien
AU - Sattler, Alexander M
AU - Schaefer, Jürgen
AU - Stark, Klaus
AU - Hengstenberg, Christian
AU - Schaefer, Arne
AU - Schreiber, Stefan
AU - Kronenberg, Florian
AU - Samani, Nilesh J
AU - Schunkert, Heribert
AU - Erdmann, Jeanette
PY - 2010
Y1 - 2010
N2 - A single nucleotide polymorphism (SNP) rs599839 located at chromosome 1p13.3 has previously been associated with risk of coronary artery disease (CAD) and with serum levels of low-density lipoprotein cholesterol (LDL-C). A functional link explaining the association of SNP rs599839 with LDL-C levels and CAD risk has not yet been elucidated.
AB - A single nucleotide polymorphism (SNP) rs599839 located at chromosome 1p13.3 has previously been associated with risk of coronary artery disease (CAD) and with serum levels of low-density lipoprotein cholesterol (LDL-C). A functional link explaining the association of SNP rs599839 with LDL-C levels and CAD risk has not yet been elucidated.
M3 - SCORING: Zeitschriftenaufsatz
VL - 208
SP - 183
EP - 189
JO - ATHEROSCLEROSIS
JF - ATHEROSCLEROSIS
SN - 0021-9150
IS - 1
M1 - 1
ER -