Gene expression analysis identifies potential biomarkers of neurofibromatosis type 1 including adrenomedullin.
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Gene expression analysis identifies potential biomarkers of neurofibromatosis type 1 including adrenomedullin. / Hummel, Trent R; Jessen, Walter J; Miller, Shyra J; Kluwe, Lan; Mautner, Viktor Felix; Wallace, Margaret R; Lázaro, Conxi; Page, Grier P; Worley, Paul F; Aronow, Bruce J; Schorry, Elizabeth K; Ratner, Nancy.
In: CLIN CANCER RES, Vol. 16, No. 20, 20, 2010, p. 5048-5057.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
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TY - JOUR
T1 - Gene expression analysis identifies potential biomarkers of neurofibromatosis type 1 including adrenomedullin.
AU - Hummel, Trent R
AU - Jessen, Walter J
AU - Miller, Shyra J
AU - Kluwe, Lan
AU - Mautner, Viktor Felix
AU - Wallace, Margaret R
AU - Lázaro, Conxi
AU - Page, Grier P
AU - Worley, Paul F
AU - Aronow, Bruce J
AU - Schorry, Elizabeth K
AU - Ratner, Nancy
PY - 2010
Y1 - 2010
N2 - Plexiform neurofibromas (pNF) are Schwann cell tumors found in a third of individuals with neurofibromatosis type 1 (NF1). pNF can undergo transformation to malignant peripheral nerve sheath tumors (MPNST). There are no identified serum biomarkers of pNF tumor burden or transformation to MPNST. Serum biomarkers would be useful to verify NF1 diagnosis, monitor tumor burden, and/or detect transformation.
AB - Plexiform neurofibromas (pNF) are Schwann cell tumors found in a third of individuals with neurofibromatosis type 1 (NF1). pNF can undergo transformation to malignant peripheral nerve sheath tumors (MPNST). There are no identified serum biomarkers of pNF tumor burden or transformation to MPNST. Serum biomarkers would be useful to verify NF1 diagnosis, monitor tumor burden, and/or detect transformation.
M3 - SCORING: Zeitschriftenaufsatz
VL - 16
SP - 5048
EP - 5057
JO - CLIN CANCER RES
JF - CLIN CANCER RES
SN - 1078-0432
IS - 20
M1 - 20
ER -