Gender differences in abdominal aortic aneurysm therapy - a systematic review
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Gender differences in abdominal aortic aneurysm therapy - a systematic review. / Stoberock, Konstanze; Kölbel, Tilo; Atlihan, Gülsen; Debus, Eike Sebastian; Tsilimparis, Nikolaos; Larena-Avellaneda, Axel; Behrendt, Christian Alexander; Wipper, Sabine.
In: VASA, Vol. 47, No. 4, 06.2018, p. 267-271.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
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TY - JOUR
T1 - Gender differences in abdominal aortic aneurysm therapy - a systematic review
AU - Stoberock, Konstanze
AU - Kölbel, Tilo
AU - Atlihan, Gülsen
AU - Debus, Eike Sebastian
AU - Tsilimparis, Nikolaos
AU - Larena-Avellaneda, Axel
AU - Behrendt, Christian Alexander
AU - Wipper, Sabine
PY - 2018/6
Y1 - 2018/6
N2 - This article analyses if and to what extent gender differences exist in abdominal aortic aneurysm (AAA) therapy. For this purpose Medline (PubMed) was searched from January 1999 to January 2018. Keywords were: "abdominal aortic aneurysm", "gender", "prevalence", "EVAR", and "open surgery of abdominal aortic aneurysm". Regardless of open or endovascular treatment of abdominal aortic aneurysms, women have a higher rate of complications and longer hospitalizations compared to men. The majority of studies showed that women have a lower survival rate for surgical and endovascular treatment of abdominal aneurysms after both elective and emergency interventions. Women receive less surgical/interventional and protective medical treatment. Women seem to have a higher risk of rupture, a lower survival rate in AAA, and a higher rate of complications, regardless of endovascular or open treatment. The gender differences may be due to a higher age of women at diagnosis and therapy associated with higher comorbidity, but also because of genetic, hormonal, anatomical, biological, and socio-cultural differences. Strategies for treatment in female patients must be further defined to optimize outcome.
AB - This article analyses if and to what extent gender differences exist in abdominal aortic aneurysm (AAA) therapy. For this purpose Medline (PubMed) was searched from January 1999 to January 2018. Keywords were: "abdominal aortic aneurysm", "gender", "prevalence", "EVAR", and "open surgery of abdominal aortic aneurysm". Regardless of open or endovascular treatment of abdominal aortic aneurysms, women have a higher rate of complications and longer hospitalizations compared to men. The majority of studies showed that women have a lower survival rate for surgical and endovascular treatment of abdominal aneurysms after both elective and emergency interventions. Women receive less surgical/interventional and protective medical treatment. Women seem to have a higher risk of rupture, a lower survival rate in AAA, and a higher rate of complications, regardless of endovascular or open treatment. The gender differences may be due to a higher age of women at diagnosis and therapy associated with higher comorbidity, but also because of genetic, hormonal, anatomical, biological, and socio-cultural differences. Strategies for treatment in female patients must be further defined to optimize outcome.
KW - Age Factors
KW - Aortic Aneurysm, Abdominal/diagnostic imaging
KW - Comorbidity
KW - Endovascular Procedures/adverse effects
KW - Female
KW - Health Status Disparities
KW - Healthcare Disparities
KW - Humans
KW - Life Style
KW - Male
KW - Postoperative Complications/mortality
KW - Risk Factors
KW - Sex Factors
KW - Treatment Outcome
KW - Vascular Surgical Procedures/adverse effects
U2 - 10.1024/0301-1526/a000703
DO - 10.1024/0301-1526/a000703
M3 - SCORING: Review article
C2 - 29733253
VL - 47
SP - 267
EP - 271
JO - VASA
JF - VASA
SN - 0301-1526
IS - 4
ER -