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Gain of chromosome region 18q21 including the MALT1 gene is associated with the activated B-cell-like gene expression subtype and increased BCL2 gene dosage and protein expression in diffuse large B-cell lymphoma.

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Gain of chromosome region 18q21 including the MALT1 gene is associated with the activated B-cell-like gene expression subtype and increased BCL2 gene dosage and protein expression in diffuse large B-cell lymphoma. / Dierlamm, Judith; Murga-Penas, Eva-Maria; Eva, M; Bentink, Stefan; Wessendorf, Swen; Berger, Hilmar; Hummel, Michael; Klapper, Wolfram; Lenze, Dido; Rosenwald, Andreas; Haralambieva, Eugenia; Ott, German; Cogliatti, Sergio B; Möller, Peter; Schwaenen, Carsten; Stein, Harald; Löffler, Markus; Spang, Rainer; Trümper, Lorenz; Siebert, Reiner.

In: HAEMATOLOGICA, Vol. 93, No. 5, 5, 2008, p. 688-696.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Dierlamm, J, Murga-Penas, E-M, Eva, M, Bentink, S, Wessendorf, S, Berger, H, Hummel, M, Klapper, W, Lenze, D, Rosenwald, A, Haralambieva, E, Ott, G, Cogliatti, SB, Möller, P, Schwaenen, C, Stein, H, Löffler, M, Spang, R, Trümper, L & Siebert, R 2008, 'Gain of chromosome region 18q21 including the MALT1 gene is associated with the activated B-cell-like gene expression subtype and increased BCL2 gene dosage and protein expression in diffuse large B-cell lymphoma.', HAEMATOLOGICA, vol. 93, no. 5, 5, pp. 688-696. https://doi.org/10.3324/haematol.12057

APA

Dierlamm, J., Murga-Penas, E-M., Eva, M., Bentink, S., Wessendorf, S., Berger, H., Hummel, M., Klapper, W., Lenze, D., Rosenwald, A., Haralambieva, E., Ott, G., Cogliatti, S. B., Möller, P., Schwaenen, C., Stein, H., Löffler, M., Spang, R., Trümper, L., & Siebert, R. (2008). Gain of chromosome region 18q21 including the MALT1 gene is associated with the activated B-cell-like gene expression subtype and increased BCL2 gene dosage and protein expression in diffuse large B-cell lymphoma. HAEMATOLOGICA, 93(5), 688-696. [5]. https://doi.org/10.3324/haematol.12057

Vancouver

Dierlamm J, Murga-Penas E-M, Eva M, Bentink S, Wessendorf S, Berger H et al. Gain of chromosome region 18q21 including the MALT1 gene is associated with the activated B-cell-like gene expression subtype and increased BCL2 gene dosage and protein expression in diffuse large B-cell lymphoma. HAEMATOLOGICA. 2008;93(5):688-696. 5. https://doi.org/10.3324/haematol.12057

Bibtex

@article{1b136837854c4e689066e9e8e540ae8a,
title = "Gain of chromosome region 18q21 including the MALT1 gene is associated with the activated B-cell-like gene expression subtype and increased BCL2 gene dosage and protein expression in diffuse large B-cell lymphoma.",
abstract = "BACKGROUND: The aim of this study was to determine the impact of a gain of the MALT1 gene on gene expression and clinical parameters in diffuse large B-cell lymphoma. DESIGN AND METHODS: We analyzed 116 cases of diffuse large B-cell lymphoma by fluorescence in situ hybridization, array-based comparative genomic hybridization, and transcriptional profiling. RESULTS: A gain of 18q21 including MALT1 was detected in 44 cases (38%) and was accompanied by a gain of BCL2 in 43 cases. All cases with a 18q21/MALT1 gain showed BCL2 protein whereas 79% in the group without a 18q21/MALT1 gain did so (p",
author = "Judith Dierlamm and Eva-Maria Murga-Penas and M Eva and Stefan Bentink and Swen Wessendorf and Hilmar Berger and Michael Hummel and Wolfram Klapper and Dido Lenze and Andreas Rosenwald and Eugenia Haralambieva and German Ott and Cogliatti, {Sergio B} and Peter M{\"o}ller and Carsten Schwaenen and Harald Stein and Markus L{\"o}ffler and Rainer Spang and Lorenz Tr{\"u}mper and Reiner Siebert",
year = "2008",
doi = "10.3324/haematol.12057",
language = "Deutsch",
volume = "93",
pages = "688--696",
journal = "HAEMATOLOGICA",
issn = "0390-6078",
publisher = "Ferrata Storti Foundation",
number = "5",

}

RIS

TY - JOUR

T1 - Gain of chromosome region 18q21 including the MALT1 gene is associated with the activated B-cell-like gene expression subtype and increased BCL2 gene dosage and protein expression in diffuse large B-cell lymphoma.

AU - Dierlamm, Judith

AU - Murga-Penas, Eva-Maria

AU - Eva, M

AU - Bentink, Stefan

AU - Wessendorf, Swen

AU - Berger, Hilmar

AU - Hummel, Michael

AU - Klapper, Wolfram

AU - Lenze, Dido

AU - Rosenwald, Andreas

AU - Haralambieva, Eugenia

AU - Ott, German

AU - Cogliatti, Sergio B

AU - Möller, Peter

AU - Schwaenen, Carsten

AU - Stein, Harald

AU - Löffler, Markus

AU - Spang, Rainer

AU - Trümper, Lorenz

AU - Siebert, Reiner

PY - 2008

Y1 - 2008

N2 - BACKGROUND: The aim of this study was to determine the impact of a gain of the MALT1 gene on gene expression and clinical parameters in diffuse large B-cell lymphoma. DESIGN AND METHODS: We analyzed 116 cases of diffuse large B-cell lymphoma by fluorescence in situ hybridization, array-based comparative genomic hybridization, and transcriptional profiling. RESULTS: A gain of 18q21 including MALT1 was detected in 44 cases (38%) and was accompanied by a gain of BCL2 in 43 cases. All cases with a 18q21/MALT1 gain showed BCL2 protein whereas 79% in the group without a 18q21/MALT1 gain did so (p

AB - BACKGROUND: The aim of this study was to determine the impact of a gain of the MALT1 gene on gene expression and clinical parameters in diffuse large B-cell lymphoma. DESIGN AND METHODS: We analyzed 116 cases of diffuse large B-cell lymphoma by fluorescence in situ hybridization, array-based comparative genomic hybridization, and transcriptional profiling. RESULTS: A gain of 18q21 including MALT1 was detected in 44 cases (38%) and was accompanied by a gain of BCL2 in 43 cases. All cases with a 18q21/MALT1 gain showed BCL2 protein whereas 79% in the group without a 18q21/MALT1 gain did so (p

U2 - 10.3324/haematol.12057

DO - 10.3324/haematol.12057

M3 - SCORING: Zeitschriftenaufsatz

VL - 93

SP - 688

EP - 696

JO - HAEMATOLOGICA

JF - HAEMATOLOGICA

SN - 0390-6078

IS - 5

M1 - 5

ER -