G2-delay after irradiation with alpha-particles as studied in synchronized cultures and by the bromodeoxyuridine-33258H technique.
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G2-delay after irradiation with alpha-particles as studied in synchronized cultures and by the bromodeoxyuridine-33258H technique. / Hieber, L; Beck-Bornholdt, Hans-Peter; Lücke-Huhle, C.
In: Cytometry, Vol. 2, No. 3, 3, 1981, p. 175-178.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
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TY - JOUR
T1 - G2-delay after irradiation with alpha-particles as studied in synchronized cultures and by the bromodeoxyuridine-33258H technique.
AU - Hieber, L
AU - Beck-Bornholdt, Hans-Peter
AU - Lücke-Huhle, C
PY - 1981
Y1 - 1981
N2 - Division delay of mouse L-929 fibroblasts after alpha-irradiation is due to a pronounced lengthening of their G2-phase. Experiments on synchronously and asynchronously growing cultures revealed a cell cycle phase-dependent sensitivity of this effect: Cells irradiated in G2 or at the G1/S border suffered a longer G2-delay than cells irradiated at mid- or late-S. Progression through G2 was nearly normal at doses up to 0.3 Gy if cells were exposed during G1 phase.
AB - Division delay of mouse L-929 fibroblasts after alpha-irradiation is due to a pronounced lengthening of their G2-phase. Experiments on synchronously and asynchronously growing cultures revealed a cell cycle phase-dependent sensitivity of this effect: Cells irradiated in G2 or at the G1/S border suffered a longer G2-delay than cells irradiated at mid- or late-S. Progression through G2 was nearly normal at doses up to 0.3 Gy if cells were exposed during G1 phase.
M3 - SCORING: Zeitschriftenaufsatz
VL - 2
SP - 175
EP - 178
IS - 3
M1 - 3
ER -
