Functional neuroimaging of inner fields-of-view with 2D-selective RF excitations

Jürgen Finsterbusch

doi:10.1016/j.mri.2013.03.005

Functional neuroimaging of inner fields-of-view with 2D-selective RF excitations

Standard

Functional neuroimaging of inner fields-of-view with 2D-selective RF excitations. / Finsterbusch, Jürgen.

In: MAGN RESON IMAGING, Vol. 31, No. 7, 01.09.2013, p. 1228-35.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Finsterbusch, J 2013, 'Functional neuroimaging of inner fields-of-view with 2D-selective RF excitations', MAGN RESON IMAGING, vol. 31, no. 7, pp. 1228-35. https://doi.org/10.1016/j.mri.2013.03.005

APA

Finsterbusch, J. (2013). Functional neuroimaging of inner fields-of-view with 2D-selective RF excitations. MAGN RESON IMAGING, 31(7), 1228-35. https://doi.org/10.1016/j.mri.2013.03.005

Vancouver

Finsterbusch J. Functional neuroimaging of inner fields-of-view with 2D-selective RF excitations. MAGN RESON IMAGING. 2013 Sep 1;31(7):1228-35. https://doi.org/10.1016/j.mri.2013.03.005

Bibtex

@article{8ebab00b55ca4ef7a07c815a6f82d372,

title = "Functional neuroimaging of inner fields-of-view with 2D-selective RF excitations",

abstract = "Echo-planar imaging is widely used in functional neuroimaging but suffers from its pronounced sensitivity to field inhomogeneities that cause geometric distortions and image blurring which both limit the effective in-plane resolution achievable. In this work, it is shown how inner-field-of-view techniques based on 2D-selective RF excitations (2DRF) can be applied to reduce the field-of-view in the phase-encoding direction without aliasing and increase the in-plane resolution accordingly. Free-induction-decay (FID) EPI and echo-train-shifted (T2*-weighted) and standard (T2-weighted) spin-echo (SE) EPI with in-plane resolutions of up to 0.5×1.0mm(2) (slice thickness 5mm) were acquired at 3T. Unwanted signal contributions of 2DRF side excitations were shifted out of the object (FID-EPI) or of the refocusing plane by tilting the excitation plane (SE-EPI). Brain activation in healthy volunteers was investigated with checkerboard and finger-tapping block-design paradigms. Brain activation could be detected with all sequences and contrasts, most reliably with FID-EPI due to its higher signal amplitude and the longer 2DRF excitation that are more sensitive to magnetic field inhomogeneities. In conclusion, inner-FOV EPI based on 2DRF excitations could help to improve the spatial resolution of fMRI of focal target regions, e.g., for applications in the spinal cord.",

keywords = "Algorithms, Brain, Brain Mapping, Echo-Planar Imaging, Functional Neuroimaging, Humans, Image Processing, Computer-Assisted, Magnetic Resonance Imaging, Phantoms, Imaging, Software",

author = "J{\"u}rgen Finsterbusch",

year = "2013",

month = sep,

day = "1",

doi = "10.1016/j.mri.2013.03.005",

language = "English",

volume = "31",

pages = "1228--35",

journal = "MAGN RESON IMAGING",

issn = "0730-725X",

publisher = "Elsevier Inc.",

number = "7",

}

RIS

TY - JOUR

T1 - Functional neuroimaging of inner fields-of-view with 2D-selective RF excitations

AU - Finsterbusch, Jürgen

PY - 2013/9/1

Y1 - 2013/9/1

N2 - Echo-planar imaging is widely used in functional neuroimaging but suffers from its pronounced sensitivity to field inhomogeneities that cause geometric distortions and image blurring which both limit the effective in-plane resolution achievable. In this work, it is shown how inner-field-of-view techniques based on 2D-selective RF excitations (2DRF) can be applied to reduce the field-of-view in the phase-encoding direction without aliasing and increase the in-plane resolution accordingly. Free-induction-decay (FID) EPI and echo-train-shifted (T2*-weighted) and standard (T2-weighted) spin-echo (SE) EPI with in-plane resolutions of up to 0.5×1.0mm(2) (slice thickness 5mm) were acquired at 3T. Unwanted signal contributions of 2DRF side excitations were shifted out of the object (FID-EPI) or of the refocusing plane by tilting the excitation plane (SE-EPI). Brain activation in healthy volunteers was investigated with checkerboard and finger-tapping block-design paradigms. Brain activation could be detected with all sequences and contrasts, most reliably with FID-EPI due to its higher signal amplitude and the longer 2DRF excitation that are more sensitive to magnetic field inhomogeneities. In conclusion, inner-FOV EPI based on 2DRF excitations could help to improve the spatial resolution of fMRI of focal target regions, e.g., for applications in the spinal cord.

AB - Echo-planar imaging is widely used in functional neuroimaging but suffers from its pronounced sensitivity to field inhomogeneities that cause geometric distortions and image blurring which both limit the effective in-plane resolution achievable. In this work, it is shown how inner-field-of-view techniques based on 2D-selective RF excitations (2DRF) can be applied to reduce the field-of-view in the phase-encoding direction without aliasing and increase the in-plane resolution accordingly. Free-induction-decay (FID) EPI and echo-train-shifted (T2*-weighted) and standard (T2-weighted) spin-echo (SE) EPI with in-plane resolutions of up to 0.5×1.0mm(2) (slice thickness 5mm) were acquired at 3T. Unwanted signal contributions of 2DRF side excitations were shifted out of the object (FID-EPI) or of the refocusing plane by tilting the excitation plane (SE-EPI). Brain activation in healthy volunteers was investigated with checkerboard and finger-tapping block-design paradigms. Brain activation could be detected with all sequences and contrasts, most reliably with FID-EPI due to its higher signal amplitude and the longer 2DRF excitation that are more sensitive to magnetic field inhomogeneities. In conclusion, inner-FOV EPI based on 2DRF excitations could help to improve the spatial resolution of fMRI of focal target regions, e.g., for applications in the spinal cord.

KW - Algorithms

KW - Brain

KW - Brain Mapping

KW - Echo-Planar Imaging

KW - Functional Neuroimaging

KW - Humans

KW - Image Processing, Computer-Assisted

KW - Magnetic Resonance Imaging

KW - Phantoms, Imaging

KW - Software

U2 - 10.1016/j.mri.2013.03.005

DO - 10.1016/j.mri.2013.03.005

M3 - SCORING: Journal article

C2 - 23602726

VL - 31

SP - 1228

EP - 1235

JO - MAGN RESON IMAGING

JF - MAGN RESON IMAGING

SN - 0730-725X

IS - 7

ER -