Functional magnetic resonance imaging and treatment strategies in schizophrenia.

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Functional magnetic resonance imaging and treatment strategies in schizophrenia. / Karch, Susanne; Pogarell, Oliver; Mulert, Christoph.

In: CURR PHARM BIOTECHNO, Vol. 13, No. 8, 8, 2012, p. 1622-1629.

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@article{51110ae14651495f9890686d162506f7,
title = "Functional magnetic resonance imaging and treatment strategies in schizophrenia.",
abstract = "Neurobiological correlates of various treatment approaches (e.g. psychopharmacology, cognitive behavioural therapy) have become an important issue in recent neuroimaging studies. In schizophrenia, dysfunctions especially in frontal and parietal brain regions as well as the ventral striatum have been demonstrated in numerous studies. The review includes functional MRI studies about neurobiological correlates of treatment effects in schizophrenic patients. Treatment-associated changes in brain activity were shown especially in the anterior cingulate cortex, the dorsolateral prefrontal cortex, the ventral striatum and the amygdala. In addition, the differential effects of various treatment approaches including different neuroleptics (atypical neuroleptics, typical neuroleptics) as well as cognitive behavioural therapy will be considered in this review. The influence of functional differences on the differential effect of typical and atypical antipsychotics on cognitive functions will be discussed.",
keywords = "Animals, Humans, Cognitive Therapy, Schizophrenic Psychology, *Magnetic Resonance Imaging, Antipsychotic Agents/therapeutic use, Schizophrenia/physiopathology/*therapy, Animals, Humans, Cognitive Therapy, Schizophrenic Psychology, *Magnetic Resonance Imaging, Antipsychotic Agents/therapeutic use, Schizophrenia/physiopathology/*therapy",
author = "Susanne Karch and Oliver Pogarell and Christoph Mulert",
year = "2012",
language = "English",
volume = "13",
pages = "1622--1629",
journal = "CURR PHARM BIOTECHNO",
issn = "1389-2010",
publisher = "Bentham Science Publishers B.V.",
number = "8",

}

RIS

TY - JOUR

T1 - Functional magnetic resonance imaging and treatment strategies in schizophrenia.

AU - Karch, Susanne

AU - Pogarell, Oliver

AU - Mulert, Christoph

PY - 2012

Y1 - 2012

N2 - Neurobiological correlates of various treatment approaches (e.g. psychopharmacology, cognitive behavioural therapy) have become an important issue in recent neuroimaging studies. In schizophrenia, dysfunctions especially in frontal and parietal brain regions as well as the ventral striatum have been demonstrated in numerous studies. The review includes functional MRI studies about neurobiological correlates of treatment effects in schizophrenic patients. Treatment-associated changes in brain activity were shown especially in the anterior cingulate cortex, the dorsolateral prefrontal cortex, the ventral striatum and the amygdala. In addition, the differential effects of various treatment approaches including different neuroleptics (atypical neuroleptics, typical neuroleptics) as well as cognitive behavioural therapy will be considered in this review. The influence of functional differences on the differential effect of typical and atypical antipsychotics on cognitive functions will be discussed.

AB - Neurobiological correlates of various treatment approaches (e.g. psychopharmacology, cognitive behavioural therapy) have become an important issue in recent neuroimaging studies. In schizophrenia, dysfunctions especially in frontal and parietal brain regions as well as the ventral striatum have been demonstrated in numerous studies. The review includes functional MRI studies about neurobiological correlates of treatment effects in schizophrenic patients. Treatment-associated changes in brain activity were shown especially in the anterior cingulate cortex, the dorsolateral prefrontal cortex, the ventral striatum and the amygdala. In addition, the differential effects of various treatment approaches including different neuroleptics (atypical neuroleptics, typical neuroleptics) as well as cognitive behavioural therapy will be considered in this review. The influence of functional differences on the differential effect of typical and atypical antipsychotics on cognitive functions will be discussed.

KW - Animals

KW - Humans

KW - Cognitive Therapy

KW - Schizophrenic Psychology

KW - Magnetic Resonance Imaging

KW - Antipsychotic Agents/therapeutic use

KW - Schizophrenia/physiopathology/therapy

KW - Animals

KW - Humans

KW - Cognitive Therapy

KW - Schizophrenic Psychology

KW - Magnetic Resonance Imaging

KW - Antipsychotic Agents/therapeutic use

KW - Schizophrenia/physiopathology/therapy

M3 - SCORING: Journal article

VL - 13

SP - 1622

EP - 1629

JO - CURR PHARM BIOTECHNO

JF - CURR PHARM BIOTECHNO

SN - 1389-2010

IS - 8

M1 - 8

ER -