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Framework and baseline examination of the German National Cohort (NAKO)

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Framework and baseline examination of the German National Cohort (NAKO). / Peters, Annette; Peters, Annette; Greiser, Karin Halina; Göttlicher, Susanne; Ahrens, Wolfgang; Albrecht, Maren; Bamberg, Fabian; Bärnighausen, Till; Becher, Heiko; Berger, Klaus; Beule, Achim; Boeing, Heiner; Bohn, Barbara; Bohnert, Kerstin; Braun, Bettina; Brenner, Hermann; Bülow, Robin; Castell, Stefanie; Damms-Machado, Antje; Dörr, Marcus; Ebert, Nina; Ecker, Margit; Emmel, Carina; Fischer, Beate; Franzke, Claus-Werner; Gastell, Sylvia; Giani, Guido; Günther, Matthias; Günther, Kathrin; Günther, Klaus-Peter; Haerting, Johannes; Haug, Ulrike; Heid, Iris M; Heier, Margit; Heinemeyer, Diana; Hendel, Thomas; Herbolsheimer, Florian; Hirsch, Jochen; Hoffmann, Wolfgang; Holleczek, Bernd; Hölling, Heike; Hörlein, Andreas; Jöckel, Karl-Heinz; Kaaks, Rudolf; Karch, André; Karrasch, Stefan; Kartschmit, Nadja; Kauczor, Hans-Ulrich; Keil, Thomas; Kemmling, Yvonne; Klee, Bianca; Klüppelholz, Birgit; Kluttig, Alexander; Kofink, Lisa; Köttgen, Anna; Kraft, Daniel; Krause, Gérard; Kretz, Lisa; Kühnisch, Jan; Kuß, Oliver; Legath, Nicole; Lehnich, Anna-Therese; Leitzmann, Michael; Lieb, Wolfgang; Linseisen, Jakob; Loeffler, Markus; Macdonald, Anke; Maier-Hein, Klaus H; Mangold, Nina; Meinke-Franze, Claudia; Meisinger, Christa; Melzer, Juliane; Mergarten, Björn; Michels, Karin B; Mikolajczyk, Rafael; Moebus, Susanne; Mueller, Ulrich; Nauck, Matthias; Niendorf, Thoralf; Nikolaou, Konstantin; Obi, Nadia; Ostrzinski, Stefan; Panreck, Leo; Pigeot, Iris; Pischon, Tobias; Pschibul-Thamm, Irene; Rathmann, Wolfgang; Reineke, Achim; Roloff, Stefanie; Rujescu, Dan; Rupf, Stefan; Sander, Oliver; Schikowski, Tamara; Schipf, Sabine; Schirmacher, Peter; Schlett, Christopher L; Schmidt, Börge; Schmidt, Georg; Schmidt, Martin; Schöne, Gina; Schulz, Holger; Schulze, Matthias B; Schweig, Alexandra; Sedlmeier, Anja M; Selder, Sonja; Six-Merker, Julia; Sowade, Ramona; Stang, Andreas; Stegle, Oliver; Steindorf, Karen; Stübs, Gunthard; Swart, Enno; Teismann, Henning; Thiele, Inke; Thierry, Sigrid; Ueffing, Marius; Völzke, Henry; Waniek, Sabina; Weber, Andrea; Werner, Nicole; Wichmann, H-Erich; Willich, Stefan N; Wirkner, Kerstin; Wolf, Kathrin; Wolff, Robert; Zeeb, Hajo; Zinkhan, Melanie; Zschocke, Johannes; NAKO Investigators.

In: EUR J EPIDEMIOL, Vol. 37, No. 10, 10.2022, p. 1107-1124.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Peters, A, Peters, A, Greiser, KH, Göttlicher, S, Ahrens, W, Albrecht, M, Bamberg, F, Bärnighausen, T, Becher, H, Berger, K, Beule, A, Boeing, H, Bohn, B, Bohnert, K, Braun, B, Brenner, H, Bülow, R, Castell, S, Damms-Machado, A, Dörr, M, Ebert, N, Ecker, M, Emmel, C, Fischer, B, Franzke, C-W, Gastell, S, Giani, G, Günther, M, Günther, K, Günther, K-P, Haerting, J, Haug, U, Heid, IM, Heier, M, Heinemeyer, D, Hendel, T, Herbolsheimer, F, Hirsch, J, Hoffmann, W, Holleczek, B, Hölling, H, Hörlein, A, Jöckel, K-H, Kaaks, R, Karch, A, Karrasch, S, Kartschmit, N, Kauczor, H-U, Keil, T, Kemmling, Y, Klee, B, Klüppelholz, B, Kluttig, A, Kofink, L, Köttgen, A, Kraft, D, Krause, G, Kretz, L, Kühnisch, J, Kuß, O, Legath, N, Lehnich, A-T, Leitzmann, M, Lieb, W, Linseisen, J, Loeffler, M, Macdonald, A, Maier-Hein, KH, Mangold, N, Meinke-Franze, C, Meisinger, C, Melzer, J, Mergarten, B, Michels, KB, Mikolajczyk, R, Moebus, S, Mueller, U, Nauck, M, Niendorf, T, Nikolaou, K, Obi, N, Ostrzinski, S, Panreck, L, Pigeot, I, Pischon, T, Pschibul-Thamm, I, Rathmann, W, Reineke, A, Roloff, S, Rujescu, D, Rupf, S, Sander, O, Schikowski, T, Schipf, S, Schirmacher, P, Schlett, CL, Schmidt, B, Schmidt, G, Schmidt, M, Schöne, G, Schulz, H, Schulze, MB, Schweig, A, Sedlmeier, AM, Selder, S, Six-Merker, J, Sowade, R, Stang, A, Stegle, O, Steindorf, K, Stübs, G, Swart, E, Teismann, H, Thiele, I, Thierry, S, Ueffing, M, Völzke, H, Waniek, S, Weber, A, Werner, N, Wichmann, H-E, Willich, SN, Wirkner, K, Wolf, K, Wolff, R, Zeeb, H, Zinkhan, M, Zschocke, J & NAKO Investigators 2022, 'Framework and baseline examination of the German National Cohort (NAKO)', EUR J EPIDEMIOL, vol. 37, no. 10, pp. 1107-1124. https://doi.org/10.1007/s10654-022-00890-5

APA

Peters, A., Peters, A., Greiser, K. H., Göttlicher, S., Ahrens, W., Albrecht, M., Bamberg, F., Bärnighausen, T., Becher, H., Berger, K., Beule, A., Boeing, H., Bohn, B., Bohnert, K., Braun, B., Brenner, H., Bülow, R., Castell, S., Damms-Machado, A., ... NAKO Investigators (2022). Framework and baseline examination of the German National Cohort (NAKO). EUR J EPIDEMIOL, 37(10), 1107-1124. https://doi.org/10.1007/s10654-022-00890-5

Vancouver

Peters A, Peters A, Greiser KH, Göttlicher S, Ahrens W, Albrecht M et al. Framework and baseline examination of the German National Cohort (NAKO). EUR J EPIDEMIOL. 2022 Oct;37(10):1107-1124. https://doi.org/10.1007/s10654-022-00890-5

Bibtex

@article{95af8d4938ad4997a4820a298d7e5171,
title = "Framework and baseline examination of the German National Cohort (NAKO)",
abstract = "The German National Cohort (NAKO) is a multidisciplinary, population-based prospective cohort study that aims to investigate the causes of widespread diseases, identify risk factors and improve early detection and prevention of disease. Specifically, NAKO is designed to identify novel and better characterize established risk and protection factors for the development of cardiovascular diseases, cancer, diabetes, neurodegenerative and psychiatric diseases, musculoskeletal diseases, respiratory and infectious diseases in a random sample of the general population. Between 2014 and 2019, a total of 205,415 men and women aged 19-74 years were recruited and examined in 18 study centres in Germany. The baseline assessment included a face-to-face interview, self-administered questionnaires and a wide range of biomedical examinations. Biomaterials were collected from all participants including serum, EDTA plasma, buffy coats, RNA and erythrocytes, urine, saliva, nasal swabs and stool. In 56,971 participants, an intensified examination programme was implemented. Whole-body 3T magnetic resonance imaging was performed in 30,861 participants on dedicated scanners. NAKO collects follow-up information on incident diseases through a combination of active follow-up using self-report via written questionnaires at 2-3 year intervals and passive follow-up via record linkages. All study participants are invited for re-examinations at the study centres in 4-5 year intervals. Thereby, longitudinal information on changes in risk factor profiles and in vascular, cardiac, metabolic, neurocognitive, pulmonary and sensory function is collected. NAKO is a major resource for population-based epidemiology to identify new and tailored strategies for early detection, prediction, prevention and treatment of major diseases for the next 30 years.",
keywords = "Male, Humans, Female, Prospective Studies, Cohort Studies, Germany/epidemiology, Surveys and Questionnaires, Self Report",
author = "Annette Peters and Annette Peters and Greiser, {Karin Halina} and Susanne G{\"o}ttlicher and Wolfgang Ahrens and Maren Albrecht and Fabian Bamberg and Till B{\"a}rnighausen and Heiko Becher and Klaus Berger and Achim Beule and Heiner Boeing and Barbara Bohn and Kerstin Bohnert and Bettina Braun and Hermann Brenner and Robin B{\"u}low and Stefanie Castell and Antje Damms-Machado and Marcus D{\"o}rr and Nina Ebert and Margit Ecker and Carina Emmel and Beate Fischer and Claus-Werner Franzke and Sylvia Gastell and Guido Giani and Matthias G{\"u}nther and Kathrin G{\"u}nther and Klaus-Peter G{\"u}nther and Johannes Haerting and Ulrike Haug and Heid, {Iris M} and Margit Heier and Diana Heinemeyer and Thomas Hendel and Florian Herbolsheimer and Jochen Hirsch and Wolfgang Hoffmann and Bernd Holleczek and Heike H{\"o}lling and Andreas H{\"o}rlein and Karl-Heinz J{\"o}ckel and Rudolf Kaaks and Andr{\'e} Karch and Stefan Karrasch and Nadja Kartschmit and Hans-Ulrich Kauczor and Thomas Keil and Yvonne Kemmling and Bianca Klee and Birgit Kl{\"u}ppelholz and Alexander Kluttig and Lisa Kofink and Anna K{\"o}ttgen and Daniel Kraft and G{\'e}rard Krause and Lisa Kretz and Jan K{\"u}hnisch and Oliver Ku{\ss} and Nicole Legath and Anna-Therese Lehnich and Michael Leitzmann and Wolfgang Lieb and Jakob Linseisen and Markus Loeffler and Anke Macdonald and Maier-Hein, {Klaus H} and Nina Mangold and Claudia Meinke-Franze and Christa Meisinger and Juliane Melzer and Bj{\"o}rn Mergarten and Michels, {Karin B} and Rafael Mikolajczyk and Susanne Moebus and Ulrich Mueller and Matthias Nauck and Thoralf Niendorf and Konstantin Nikolaou and Nadia Obi and Stefan Ostrzinski and Leo Panreck and Iris Pigeot and Tobias Pischon and Irene Pschibul-Thamm and Wolfgang Rathmann and Achim Reineke and Stefanie Roloff and Dan Rujescu and Stefan Rupf and Oliver Sander and Tamara Schikowski and Sabine Schipf and Peter Schirmacher and Schlett, {Christopher L} and B{\"o}rge Schmidt and Georg Schmidt and Martin Schmidt and Gina Sch{\"o}ne and Holger Schulz and Schulze, {Matthias B} and Alexandra Schweig and Sedlmeier, {Anja M} and Sonja Selder and Julia Six-Merker and Ramona Sowade and Andreas Stang and Oliver Stegle and Karen Steindorf and Gunthard St{\"u}bs and Enno Swart and Henning Teismann and Inke Thiele and Sigrid Thierry and Marius Ueffing and Henry V{\"o}lzke and Sabina Waniek and Andrea Weber and Nicole Werner and H-Erich Wichmann and Willich, {Stefan N} and Kerstin Wirkner and Kathrin Wolf and Robert Wolff and Hajo Zeeb and Melanie Zinkhan and Johannes Zschocke and {NAKO Investigators}",
note = "{\textcopyright} 2022. The Author(s).",
year = "2022",
month = oct,
doi = "10.1007/s10654-022-00890-5",
language = "English",
volume = "37",
pages = "1107--1124",
journal = "EUR J EPIDEMIOL",
issn = "0393-2990",
publisher = "Springer",
number = "10",

}

RIS

TY - JOUR

T1 - Framework and baseline examination of the German National Cohort (NAKO)

AU - Peters, Annette

AU - Peters, Annette

AU - Greiser, Karin Halina

AU - Göttlicher, Susanne

AU - Ahrens, Wolfgang

AU - Albrecht, Maren

AU - Bamberg, Fabian

AU - Bärnighausen, Till

AU - Becher, Heiko

AU - Berger, Klaus

AU - Beule, Achim

AU - Boeing, Heiner

AU - Bohn, Barbara

AU - Bohnert, Kerstin

AU - Braun, Bettina

AU - Brenner, Hermann

AU - Bülow, Robin

AU - Castell, Stefanie

AU - Damms-Machado, Antje

AU - Dörr, Marcus

AU - Ebert, Nina

AU - Ecker, Margit

AU - Emmel, Carina

AU - Fischer, Beate

AU - Franzke, Claus-Werner

AU - Gastell, Sylvia

AU - Giani, Guido

AU - Günther, Matthias

AU - Günther, Kathrin

AU - Günther, Klaus-Peter

AU - Haerting, Johannes

AU - Haug, Ulrike

AU - Heid, Iris M

AU - Heier, Margit

AU - Heinemeyer, Diana

AU - Hendel, Thomas

AU - Herbolsheimer, Florian

AU - Hirsch, Jochen

AU - Hoffmann, Wolfgang

AU - Holleczek, Bernd

AU - Hölling, Heike

AU - Hörlein, Andreas

AU - Jöckel, Karl-Heinz

AU - Kaaks, Rudolf

AU - Karch, André

AU - Karrasch, Stefan

AU - Kartschmit, Nadja

AU - Kauczor, Hans-Ulrich

AU - Keil, Thomas

AU - Kemmling, Yvonne

AU - Klee, Bianca

AU - Klüppelholz, Birgit

AU - Kluttig, Alexander

AU - Kofink, Lisa

AU - Köttgen, Anna

AU - Kraft, Daniel

AU - Krause, Gérard

AU - Kretz, Lisa

AU - Kühnisch, Jan

AU - Kuß, Oliver

AU - Legath, Nicole

AU - Lehnich, Anna-Therese

AU - Leitzmann, Michael

AU - Lieb, Wolfgang

AU - Linseisen, Jakob

AU - Loeffler, Markus

AU - Macdonald, Anke

AU - Maier-Hein, Klaus H

AU - Mangold, Nina

AU - Meinke-Franze, Claudia

AU - Meisinger, Christa

AU - Melzer, Juliane

AU - Mergarten, Björn

AU - Michels, Karin B

AU - Mikolajczyk, Rafael

AU - Moebus, Susanne

AU - Mueller, Ulrich

AU - Nauck, Matthias

AU - Niendorf, Thoralf

AU - Nikolaou, Konstantin

AU - Obi, Nadia

AU - Ostrzinski, Stefan

AU - Panreck, Leo

AU - Pigeot, Iris

AU - Pischon, Tobias

AU - Pschibul-Thamm, Irene

AU - Rathmann, Wolfgang

AU - Reineke, Achim

AU - Roloff, Stefanie

AU - Rujescu, Dan

AU - Rupf, Stefan

AU - Sander, Oliver

AU - Schikowski, Tamara

AU - Schipf, Sabine

AU - Schirmacher, Peter

AU - Schlett, Christopher L

AU - Schmidt, Börge

AU - Schmidt, Georg

AU - Schmidt, Martin

AU - Schöne, Gina

AU - Schulz, Holger

AU - Schulze, Matthias B

AU - Schweig, Alexandra

AU - Sedlmeier, Anja M

AU - Selder, Sonja

AU - Six-Merker, Julia

AU - Sowade, Ramona

AU - Stang, Andreas

AU - Stegle, Oliver

AU - Steindorf, Karen

AU - Stübs, Gunthard

AU - Swart, Enno

AU - Teismann, Henning

AU - Thiele, Inke

AU - Thierry, Sigrid

AU - Ueffing, Marius

AU - Völzke, Henry

AU - Waniek, Sabina

AU - Weber, Andrea

AU - Werner, Nicole

AU - Wichmann, H-Erich

AU - Willich, Stefan N

AU - Wirkner, Kerstin

AU - Wolf, Kathrin

AU - Wolff, Robert

AU - Zeeb, Hajo

AU - Zinkhan, Melanie

AU - Zschocke, Johannes

AU - NAKO Investigators

N1 - © 2022. The Author(s).

PY - 2022/10

Y1 - 2022/10

N2 - The German National Cohort (NAKO) is a multidisciplinary, population-based prospective cohort study that aims to investigate the causes of widespread diseases, identify risk factors and improve early detection and prevention of disease. Specifically, NAKO is designed to identify novel and better characterize established risk and protection factors for the development of cardiovascular diseases, cancer, diabetes, neurodegenerative and psychiatric diseases, musculoskeletal diseases, respiratory and infectious diseases in a random sample of the general population. Between 2014 and 2019, a total of 205,415 men and women aged 19-74 years were recruited and examined in 18 study centres in Germany. The baseline assessment included a face-to-face interview, self-administered questionnaires and a wide range of biomedical examinations. Biomaterials were collected from all participants including serum, EDTA plasma, buffy coats, RNA and erythrocytes, urine, saliva, nasal swabs and stool. In 56,971 participants, an intensified examination programme was implemented. Whole-body 3T magnetic resonance imaging was performed in 30,861 participants on dedicated scanners. NAKO collects follow-up information on incident diseases through a combination of active follow-up using self-report via written questionnaires at 2-3 year intervals and passive follow-up via record linkages. All study participants are invited for re-examinations at the study centres in 4-5 year intervals. Thereby, longitudinal information on changes in risk factor profiles and in vascular, cardiac, metabolic, neurocognitive, pulmonary and sensory function is collected. NAKO is a major resource for population-based epidemiology to identify new and tailored strategies for early detection, prediction, prevention and treatment of major diseases for the next 30 years.

AB - The German National Cohort (NAKO) is a multidisciplinary, population-based prospective cohort study that aims to investigate the causes of widespread diseases, identify risk factors and improve early detection and prevention of disease. Specifically, NAKO is designed to identify novel and better characterize established risk and protection factors for the development of cardiovascular diseases, cancer, diabetes, neurodegenerative and psychiatric diseases, musculoskeletal diseases, respiratory and infectious diseases in a random sample of the general population. Between 2014 and 2019, a total of 205,415 men and women aged 19-74 years were recruited and examined in 18 study centres in Germany. The baseline assessment included a face-to-face interview, self-administered questionnaires and a wide range of biomedical examinations. Biomaterials were collected from all participants including serum, EDTA plasma, buffy coats, RNA and erythrocytes, urine, saliva, nasal swabs and stool. In 56,971 participants, an intensified examination programme was implemented. Whole-body 3T magnetic resonance imaging was performed in 30,861 participants on dedicated scanners. NAKO collects follow-up information on incident diseases through a combination of active follow-up using self-report via written questionnaires at 2-3 year intervals and passive follow-up via record linkages. All study participants are invited for re-examinations at the study centres in 4-5 year intervals. Thereby, longitudinal information on changes in risk factor profiles and in vascular, cardiac, metabolic, neurocognitive, pulmonary and sensory function is collected. NAKO is a major resource for population-based epidemiology to identify new and tailored strategies for early detection, prediction, prevention and treatment of major diseases for the next 30 years.

KW - Male

KW - Humans

KW - Female

KW - Prospective Studies

KW - Cohort Studies

KW - Germany/epidemiology

KW - Surveys and Questionnaires

KW - Self Report

U2 - 10.1007/s10654-022-00890-5

DO - 10.1007/s10654-022-00890-5

M3 - SCORING: Journal article

C2 - 36260190

VL - 37

SP - 1107

EP - 1124

JO - EUR J EPIDEMIOL

JF - EUR J EPIDEMIOL

SN - 0393-2990

IS - 10

ER -