Fracture prevention by femoroplasty--cement augmentation of the proximal femur.
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Fracture prevention by femoroplasty--cement augmentation of the proximal femur. / Beckmann, J; Springorum, R; Vettorazzi, Eik; Bachmeier, S; Lüring, C; Tingart, M; Püschel, Klaus; Stark, Olaf Alexander; Grifka, J; Gehrke, T; Amling, Michael; Gebauer, Matthias.
In: J ORTHOP RES, Vol. 29, No. 11, 11, 2011, p. 1753-1758.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
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TY - JOUR
T1 - Fracture prevention by femoroplasty--cement augmentation of the proximal femur.
AU - Beckmann, J
AU - Springorum, R
AU - Vettorazzi, Eik
AU - Bachmeier, S
AU - Lüring, C
AU - Tingart, M
AU - Püschel, Klaus
AU - Stark, Olaf Alexander
AU - Grifka, J
AU - Gehrke, T
AU - Amling, Michael
AU - Gebauer, Matthias
PY - 2011
Y1 - 2011
N2 - The prevention of hip fractures is a desirable goal to reduce morbidity, mortality, and socio-economic burden. We evaluated the influence on femoral strength of different clinically applicable cementing techniques as "femoroplasty." Twenty-eight human cadaveric femora were augmented by means of four clinically applicable percutaneous cementing techniques and then tested biomechanically against their native contralateral control to determine fracture strength in an established biomechanical model mimicking a fall on the greater trochanter. The energy applied until fracture could be significantly increased by two of the methods by 160% (53.1?Nm vs. 20.4?Nm, p?<?0.001) and 164% (47.1?Nm vs. 17.8?Nm, p?=?0.008), respectively. The peak load to failure was significantly increased by three of the methods by 23% (3818.3?N vs. 3095.7?N, p?=?0.003), 35% (3698.4?N vs. 2737.5?N, p?=?0.007), and 12% (3056.8?N vs. 2742.8?N, p?=?0.005), respectively. The femora augmented with cemented double drill holes had a lower fracture strength than the single drilled ones. Experimental femoroplasty is a technically feasible procedure for the prophylactic reinforcement of the osteoporotic proximal femur and, hence, could be an auxiliary treatment option to protect the proximal femur against osteoporotic fractures.
AB - The prevention of hip fractures is a desirable goal to reduce morbidity, mortality, and socio-economic burden. We evaluated the influence on femoral strength of different clinically applicable cementing techniques as "femoroplasty." Twenty-eight human cadaveric femora were augmented by means of four clinically applicable percutaneous cementing techniques and then tested biomechanically against their native contralateral control to determine fracture strength in an established biomechanical model mimicking a fall on the greater trochanter. The energy applied until fracture could be significantly increased by two of the methods by 160% (53.1?Nm vs. 20.4?Nm, p?<?0.001) and 164% (47.1?Nm vs. 17.8?Nm, p?=?0.008), respectively. The peak load to failure was significantly increased by three of the methods by 23% (3818.3?N vs. 3095.7?N, p?=?0.003), 35% (3698.4?N vs. 2737.5?N, p?=?0.007), and 12% (3056.8?N vs. 2742.8?N, p?=?0.005), respectively. The femora augmented with cemented double drill holes had a lower fracture strength than the single drilled ones. Experimental femoroplasty is a technically feasible procedure for the prophylactic reinforcement of the osteoporotic proximal femur and, hence, could be an auxiliary treatment option to protect the proximal femur against osteoporotic fractures.
KW - Humans
KW - Male
KW - Aged
KW - Female
KW - Cadaver
KW - Stress, Mechanical
KW - Weight-Bearing/physiology
KW - Accidental Falls
KW - Biomechanics/physiology
KW - Bone Cements/pharmacology
KW - Femur Head/injuries/physiology/radiography
KW - Hip Fractures/physiopathology/prevention & control/radiography
KW - Osteoporosis/complications
KW - Humans
KW - Male
KW - Aged
KW - Female
KW - Cadaver
KW - Stress, Mechanical
KW - Weight-Bearing/physiology
KW - Accidental Falls
KW - Biomechanics/physiology
KW - Bone Cements/pharmacology
KW - Femur Head/injuries/physiology/radiography
KW - Hip Fractures/physiopathology/prevention & control/radiography
KW - Osteoporosis/complications
M3 - SCORING: Journal article
VL - 29
SP - 1753
EP - 1758
JO - J ORTHOP RES
JF - J ORTHOP RES
SN - 0736-0266
IS - 11
M1 - 11
ER -
