Foreign Body Abscess Mimicking a Malignant Peripheral Nerve Sheath Tumor in a Patient With Neurofibromatosis Type 1
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Foreign Body Abscess Mimicking a Malignant Peripheral Nerve Sheath Tumor in a Patient With Neurofibromatosis Type 1. / Salamon, Johannes; Hagel, Christian; Friedrich, Reinhard E; Mautner, Viktor-Felix; Derlin, Thorsten.
In: CLIN NUCL MED, Vol. 40, No. 8, 08.2015, p. 674-675.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
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TY - JOUR
T1 - Foreign Body Abscess Mimicking a Malignant Peripheral Nerve Sheath Tumor in a Patient With Neurofibromatosis Type 1
AU - Salamon, Johannes
AU - Hagel, Christian
AU - Friedrich, Reinhard E
AU - Mautner, Viktor-Felix
AU - Derlin, Thorsten
PY - 2015/8
Y1 - 2015/8
N2 - We report a case of a 47-year-old man with neurofibromatosis type 1 presenting with a growing and painful lesion within the right thigh, suggesting a malignant peripheral nerve sheath tumor. MRI showed a T2-weighted hyperintense lesion with surrounding edema and contrast enhancement. F-FDG PET/CT demonstrated inhomogeneously increased tracer uptake within the right thigh. Histopathologic evaluation revealed a foreign body with purulent fibroinflammatory reaction. F-FDG PET/CT is a highly sensitive tool for detection of malignant transformation in neurofibromatosis type 1, but false-positive findings may be observed in benign lesions, for example, inflammatory processes.
AB - We report a case of a 47-year-old man with neurofibromatosis type 1 presenting with a growing and painful lesion within the right thigh, suggesting a malignant peripheral nerve sheath tumor. MRI showed a T2-weighted hyperintense lesion with surrounding edema and contrast enhancement. F-FDG PET/CT demonstrated inhomogeneously increased tracer uptake within the right thigh. Histopathologic evaluation revealed a foreign body with purulent fibroinflammatory reaction. F-FDG PET/CT is a highly sensitive tool for detection of malignant transformation in neurofibromatosis type 1, but false-positive findings may be observed in benign lesions, for example, inflammatory processes.
U2 - 10.1097/RLU.0000000000000824
DO - 10.1097/RLU.0000000000000824
M3 - SCORING: Journal article
C2 - 26018702
VL - 40
SP - 674
EP - 675
JO - CLIN NUCL MED
JF - CLIN NUCL MED
SN - 0363-9762
IS - 8
ER -