Focus on a rare clinical entity: unicuspid aortic valve disease

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Focus on a rare clinical entity: unicuspid aortic valve disease. / Naito, Shiho; Sequeira-Gross, Tatiana; Petersen, Johannes; Holst, Theresa; Reichenspurner, Hermann; Girdauskas, Evaldas.

In: EXPERT REV CARDIOVAS, Vol. 18, No. 9, 09.2020, p. 625-633.

Research output: SCORING: Contribution to journalSCORING: Review articleResearch

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@article{4fe168f5f46047388ea213caa4664488,
title = "Focus on a rare clinical entity: unicuspid aortic valve disease",
abstract = "INTRODUCTION: While the understanding of the pathophysiology and clinical implication of bicuspid aortic valves evolves rapidly, the natural history of unicuspid aortic valves is still poorly understood. Hence, a universally accepted diagnostic work-up process and therapy recommendations for UAV still have to be established.AREAS COVERED: This article aims to give an overview on the most recent literature addressing the pathophysiology, the diagnostic tools and appropriate surgical therapy options of unicuspid aortic valve. Due to the rare prevalence, the understanding of pathophysiology is still missing. Further, symptomatic aortic valve disease are seen much earlier life stage in this cohorts. Thus, it highlights the several surgical treatment options with pro and contra especially for the young adult cohorts.EXPERT OPINION: Large scale prospective observational studies using standardized diagnostic criteria are needed to reveal the clinical course. Further appropriate treatment strategies of unicuspid aortic valve patients is demanded.",
keywords = "Aortic Valve/physiopathology, Aortic Valve Disease/physiopathology, Heart Valve Diseases/physiopathology, Humans, Young Adult",
author = "Shiho Naito and Tatiana Sequeira-Gross and Johannes Petersen and Theresa Holst and Hermann Reichenspurner and Evaldas Girdauskas",
year = "2020",
month = sep,
doi = "10.1080/14779072.2020.1811685",
language = "English",
volume = "18",
pages = "625--633",
journal = "EXPERT REV CARDIOVAS",
issn = "1477-9072",
publisher = "Taylor and Francis Ltd.",
number = "9",

}

RIS

TY - JOUR

T1 - Focus on a rare clinical entity: unicuspid aortic valve disease

AU - Naito, Shiho

AU - Sequeira-Gross, Tatiana

AU - Petersen, Johannes

AU - Holst, Theresa

AU - Reichenspurner, Hermann

AU - Girdauskas, Evaldas

PY - 2020/9

Y1 - 2020/9

N2 - INTRODUCTION: While the understanding of the pathophysiology and clinical implication of bicuspid aortic valves evolves rapidly, the natural history of unicuspid aortic valves is still poorly understood. Hence, a universally accepted diagnostic work-up process and therapy recommendations for UAV still have to be established.AREAS COVERED: This article aims to give an overview on the most recent literature addressing the pathophysiology, the diagnostic tools and appropriate surgical therapy options of unicuspid aortic valve. Due to the rare prevalence, the understanding of pathophysiology is still missing. Further, symptomatic aortic valve disease are seen much earlier life stage in this cohorts. Thus, it highlights the several surgical treatment options with pro and contra especially for the young adult cohorts.EXPERT OPINION: Large scale prospective observational studies using standardized diagnostic criteria are needed to reveal the clinical course. Further appropriate treatment strategies of unicuspid aortic valve patients is demanded.

AB - INTRODUCTION: While the understanding of the pathophysiology and clinical implication of bicuspid aortic valves evolves rapidly, the natural history of unicuspid aortic valves is still poorly understood. Hence, a universally accepted diagnostic work-up process and therapy recommendations for UAV still have to be established.AREAS COVERED: This article aims to give an overview on the most recent literature addressing the pathophysiology, the diagnostic tools and appropriate surgical therapy options of unicuspid aortic valve. Due to the rare prevalence, the understanding of pathophysiology is still missing. Further, symptomatic aortic valve disease are seen much earlier life stage in this cohorts. Thus, it highlights the several surgical treatment options with pro and contra especially for the young adult cohorts.EXPERT OPINION: Large scale prospective observational studies using standardized diagnostic criteria are needed to reveal the clinical course. Further appropriate treatment strategies of unicuspid aortic valve patients is demanded.

KW - Aortic Valve/physiopathology

KW - Aortic Valve Disease/physiopathology

KW - Heart Valve Diseases/physiopathology

KW - Humans

KW - Young Adult

U2 - 10.1080/14779072.2020.1811685

DO - 10.1080/14779072.2020.1811685

M3 - SCORING: Review article

C2 - 32811206

VL - 18

SP - 625

EP - 633

JO - EXPERT REV CARDIOVAS

JF - EXPERT REV CARDIOVAS

SN - 1477-9072

IS - 9

ER -