Female gender does not increase perioperative risk in coronary bypass surgery

H Gulbins; I C Ennker; A Malkoc; J C Ennker

doi:10.1055/s-0030-1249924

Female gender does not increase perioperative risk in coronary bypass surgery

Standard

Female gender does not increase perioperative risk in coronary bypass surgery. / Gulbins, H; Ennker, I C; Malkoc, A; Ennker, J C.

In: THORAC CARDIOV SURG, Vol. 58, No. 7, 10.2010, p. 403-407.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Gulbins, H, Ennker, IC, Malkoc, A & Ennker, JC 2010, 'Female gender does not increase perioperative risk in coronary bypass surgery', THORAC CARDIOV SURG, vol. 58, no. 7, pp. 403-407. https://doi.org/10.1055/s-0030-1249924

APA

Gulbins, H., Ennker, I. C., Malkoc, A., & Ennker, J. C. (2010). Female gender does not increase perioperative risk in coronary bypass surgery. THORAC CARDIOV SURG, 58(7), 403-407. https://doi.org/10.1055/s-0030-1249924

Vancouver

Gulbins H, Ennker IC, Malkoc A, Ennker JC. Female gender does not increase perioperative risk in coronary bypass surgery. THORAC CARDIOV SURG. 2010 Oct;58(7):403-407. https://doi.org/10.1055/s-0030-1249924

Bibtex

@article{e12a79942c754c1c9776d34b25102e49,

title = "Female gender does not increase perioperative risk in coronary bypass surgery",

abstract = "INTRODUCTION: Female gender has been identified as an independent risk factor for perioperative mortality in several risk scores for cardiac surgery. Since no explanation has been given for this, this study aimed to evaluate potential differences in the distribution of other risk factors between the genders.PATIENTS AND METHODS: 10 714 consecutive coronary bypass patients were analyzed retrospectively. The distribution of the risk factors as used in the EuroSCORE was evaluated. Diabetes mellitus was added to the analysis as an additional risk factor. Patients aged between 60 and 70 years without any additional risk factors were directly compared in a subgroup analysis. Statistical analysis was done using the T-test or chi-square test where appropriate.RESULTS: Female patients were significantly older compared to male ones (69.1 ± 8.5 vs. 65.4 ± 4 years, P < 0.05). The distribution of the analyzed risk factors did not differ except for diabetes mellitus: female patients were more likely to present with diabetes (42 % vs. 29 %, P < 0.05) and in diabetic patients, the incidence of insulin dependency was higher in female patients (50 % vs. 33 %, P < 0.05). Overall perioperative mortality was higher in female patients (2.7 % vs. 1.8 %, P < 0.05). This difference increased when diabetes was present (3.9 % vs. 1.8 %, P < 0.05) and was even higher in insulin-dependent patients (4.9 % vs. 1.9 %, P < 0.05). However, when adjusting for age and diabetes, the differences were reduced. This was most evident when subgroups of age-adjusted patients without any additional risk factors were analyzed: no gender-specific difference in perioperative mortality was observed.CONCLUSIONS: Female gender itself did not present as an independent risk factor. The presence of diabetes mellitus increased the risk in female patients significantly more than in male patients. The higher prevalence of diabetes in female patients in combination with the older age at presentation might result in the higher overall mortality observed in female patients compared to men.",

keywords = "Age Factors, Aged, Chi-Square Distribution, Coronary Artery Bypass/mortality, Diabetes Mellitus, Type 1/complications, Female, Germany, Hospital Mortality, Humans, Male, Middle Aged, Prevalence, Retrospective Studies, Risk Assessment, Risk Factors, Sex Factors, Time Factors, Treatment Outcome",

author = "H Gulbins and Ennker, {I C} and A Malkoc and Ennker, {J C}",

note = "{\textcopyright} Georg Thieme Verlag KG Stuttgart · New York.",

year = "2010",

month = oct,

doi = "10.1055/s-0030-1249924",

language = "English",

volume = "58",

pages = "403--407",

journal = "THORAC CARDIOV SURG",

issn = "0171-6425",

publisher = "Georg Thieme Verlag KG",

number = "7",

}

RIS

TY - JOUR

T1 - Female gender does not increase perioperative risk in coronary bypass surgery

AU - Gulbins, H

AU - Ennker, I C

AU - Malkoc, A

AU - Ennker, J C

N1 - © Georg Thieme Verlag KG Stuttgart · New York.

PY - 2010/10

Y1 - 2010/10

N2 - INTRODUCTION: Female gender has been identified as an independent risk factor for perioperative mortality in several risk scores for cardiac surgery. Since no explanation has been given for this, this study aimed to evaluate potential differences in the distribution of other risk factors between the genders.PATIENTS AND METHODS: 10 714 consecutive coronary bypass patients were analyzed retrospectively. The distribution of the risk factors as used in the EuroSCORE was evaluated. Diabetes mellitus was added to the analysis as an additional risk factor. Patients aged between 60 and 70 years without any additional risk factors were directly compared in a subgroup analysis. Statistical analysis was done using the T-test or chi-square test where appropriate.RESULTS: Female patients were significantly older compared to male ones (69.1 ± 8.5 vs. 65.4 ± 4 years, P < 0.05). The distribution of the analyzed risk factors did not differ except for diabetes mellitus: female patients were more likely to present with diabetes (42 % vs. 29 %, P < 0.05) and in diabetic patients, the incidence of insulin dependency was higher in female patients (50 % vs. 33 %, P < 0.05). Overall perioperative mortality was higher in female patients (2.7 % vs. 1.8 %, P < 0.05). This difference increased when diabetes was present (3.9 % vs. 1.8 %, P < 0.05) and was even higher in insulin-dependent patients (4.9 % vs. 1.9 %, P < 0.05). However, when adjusting for age and diabetes, the differences were reduced. This was most evident when subgroups of age-adjusted patients without any additional risk factors were analyzed: no gender-specific difference in perioperative mortality was observed.CONCLUSIONS: Female gender itself did not present as an independent risk factor. The presence of diabetes mellitus increased the risk in female patients significantly more than in male patients. The higher prevalence of diabetes in female patients in combination with the older age at presentation might result in the higher overall mortality observed in female patients compared to men.

AB - INTRODUCTION: Female gender has been identified as an independent risk factor for perioperative mortality in several risk scores for cardiac surgery. Since no explanation has been given for this, this study aimed to evaluate potential differences in the distribution of other risk factors between the genders.PATIENTS AND METHODS: 10 714 consecutive coronary bypass patients were analyzed retrospectively. The distribution of the risk factors as used in the EuroSCORE was evaluated. Diabetes mellitus was added to the analysis as an additional risk factor. Patients aged between 60 and 70 years without any additional risk factors were directly compared in a subgroup analysis. Statistical analysis was done using the T-test or chi-square test where appropriate.RESULTS: Female patients were significantly older compared to male ones (69.1 ± 8.5 vs. 65.4 ± 4 years, P < 0.05). The distribution of the analyzed risk factors did not differ except for diabetes mellitus: female patients were more likely to present with diabetes (42 % vs. 29 %, P < 0.05) and in diabetic patients, the incidence of insulin dependency was higher in female patients (50 % vs. 33 %, P < 0.05). Overall perioperative mortality was higher in female patients (2.7 % vs. 1.8 %, P < 0.05). This difference increased when diabetes was present (3.9 % vs. 1.8 %, P < 0.05) and was even higher in insulin-dependent patients (4.9 % vs. 1.9 %, P < 0.05). However, when adjusting for age and diabetes, the differences were reduced. This was most evident when subgroups of age-adjusted patients without any additional risk factors were analyzed: no gender-specific difference in perioperative mortality was observed.CONCLUSIONS: Female gender itself did not present as an independent risk factor. The presence of diabetes mellitus increased the risk in female patients significantly more than in male patients. The higher prevalence of diabetes in female patients in combination with the older age at presentation might result in the higher overall mortality observed in female patients compared to men.

KW - Age Factors

KW - Aged

KW - Chi-Square Distribution

KW - Coronary Artery Bypass/mortality

KW - Diabetes Mellitus, Type 1/complications

KW - Female

KW - Germany

KW - Hospital Mortality

KW - Humans

KW - Male

KW - Middle Aged

KW - Prevalence

KW - Retrospective Studies

KW - Risk Assessment

KW - Risk Factors

KW - Sex Factors

KW - Time Factors

KW - Treatment Outcome

U2 - 10.1055/s-0030-1249924

DO - 10.1055/s-0030-1249924

M3 - SCORING: Journal article

C2 - 20922623

VL - 58

SP - 403

EP - 407

JO - THORAC CARDIOV SURG

JF - THORAC CARDIOV SURG

SN - 0171-6425

IS - 7

ER -