Feedforward somatosensory inhibition is normal in cervical dystonia

Elisa R Ferrè; Christos Ganos; Kailash P Bhatia; Patrick Haggard

doi:10.1016/j.parkreldis.2014.12.026

Feedforward somatosensory inhibition is normal in cervical dystonia

Standard

Feedforward somatosensory inhibition is normal in cervical dystonia. / Ferrè, Elisa R; Ganos, Christos; Bhatia, Kailash P; Haggard, Patrick.

In: PARKINSONISM RELAT D, Vol. 21, No. 3, 01.03.2015, p. 266-70.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Ferrè, ER, Ganos, C, Bhatia, KP & Haggard, P 2015, 'Feedforward somatosensory inhibition is normal in cervical dystonia', PARKINSONISM RELAT D, vol. 21, no. 3, pp. 266-70. https://doi.org/10.1016/j.parkreldis.2014.12.026

APA

Ferrè, E. R., Ganos, C., Bhatia, K. P., & Haggard, P. (2015). Feedforward somatosensory inhibition is normal in cervical dystonia. PARKINSONISM RELAT D, 21(3), 266-70. https://doi.org/10.1016/j.parkreldis.2014.12.026

Vancouver

Ferrè ER, Ganos C, Bhatia KP, Haggard P. Feedforward somatosensory inhibition is normal in cervical dystonia. PARKINSONISM RELAT D. 2015 Mar 1;21(3):266-70. https://doi.org/10.1016/j.parkreldis.2014.12.026

Bibtex

@article{eb90f7c186a74c82a1e541d10769c890,

title = "Feedforward somatosensory inhibition is normal in cervical dystonia",

abstract = "BACKGROUND: Insufficient cortical inhibition is a key pathophysiological finding in dystonia. Subliminal sensory stimuli were reported to transiently inhibit somatosensory processing. Here we investigated whether such subliminal feedforward inhibition is reduced in patients with cervical dystonia.METHODS: Sixteen cervical dystonia patients and 16 matched healthy controls performed a somatosensory detection task. We measured the drop in sensitivity to detect a threshold-level digital nerve shock when it was preceded by a subliminal conditioning shock, compared to when it was not.RESULTS: Subliminal conditioning shocks reduced sensitivity to threshold stimuli to a similar extent in both patients and controls, suggesting that somatosensory subliminal feedforward inhibition is normal in cervical dystonia.CONCLUSION: Somatosensory feedforward inhibition was normal in this group of cervical dystonia patients. Our results qualify previous concepts of a general dystonic deficit in sensorimotor inhibitory processing.",

author = "Ferr{\`e}, {Elisa R} and Christos Ganos and Bhatia, {Kailash P} and Patrick Haggard",

year = "2015",

month = mar,

day = "1",

doi = "10.1016/j.parkreldis.2014.12.026",

language = "English",

volume = "21",

pages = "266--70",

journal = "PARKINSONISM RELAT D",

issn = "1353-8020",

publisher = "Elsevier BV",

number = "3",

}

RIS

TY - JOUR

T1 - Feedforward somatosensory inhibition is normal in cervical dystonia

AU - Ferrè, Elisa R

AU - Ganos, Christos

AU - Bhatia, Kailash P

AU - Haggard, Patrick

PY - 2015/3/1

Y1 - 2015/3/1

N2 - BACKGROUND: Insufficient cortical inhibition is a key pathophysiological finding in dystonia. Subliminal sensory stimuli were reported to transiently inhibit somatosensory processing. Here we investigated whether such subliminal feedforward inhibition is reduced in patients with cervical dystonia.METHODS: Sixteen cervical dystonia patients and 16 matched healthy controls performed a somatosensory detection task. We measured the drop in sensitivity to detect a threshold-level digital nerve shock when it was preceded by a subliminal conditioning shock, compared to when it was not.RESULTS: Subliminal conditioning shocks reduced sensitivity to threshold stimuli to a similar extent in both patients and controls, suggesting that somatosensory subliminal feedforward inhibition is normal in cervical dystonia.CONCLUSION: Somatosensory feedforward inhibition was normal in this group of cervical dystonia patients. Our results qualify previous concepts of a general dystonic deficit in sensorimotor inhibitory processing.

AB - BACKGROUND: Insufficient cortical inhibition is a key pathophysiological finding in dystonia. Subliminal sensory stimuli were reported to transiently inhibit somatosensory processing. Here we investigated whether such subliminal feedforward inhibition is reduced in patients with cervical dystonia.METHODS: Sixteen cervical dystonia patients and 16 matched healthy controls performed a somatosensory detection task. We measured the drop in sensitivity to detect a threshold-level digital nerve shock when it was preceded by a subliminal conditioning shock, compared to when it was not.RESULTS: Subliminal conditioning shocks reduced sensitivity to threshold stimuli to a similar extent in both patients and controls, suggesting that somatosensory subliminal feedforward inhibition is normal in cervical dystonia.CONCLUSION: Somatosensory feedforward inhibition was normal in this group of cervical dystonia patients. Our results qualify previous concepts of a general dystonic deficit in sensorimotor inhibitory processing.

U2 - 10.1016/j.parkreldis.2014.12.026

DO - 10.1016/j.parkreldis.2014.12.026

M3 - SCORING: Journal article

C2 - 25601129

VL - 21

SP - 266

EP - 270

JO - PARKINSONISM RELAT D

JF - PARKINSONISM RELAT D

SN - 1353-8020

IS - 3

ER -