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Feasibility of extremely reduced-dose CT of the thoracic spine in human cadavers

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Feasibility of extremely reduced-dose CT of the thoracic spine in human cadavers. / Weinrich, Julius Matthias; Warncke, Malte; Wiese, Nis; Regier, Marc; Tahir, Enver; Heinemann, Axel; Sehner, Susanne; Püschel, Klaus; Adam, Gerhard; Laqmani, Azien.

In: ACTA RADIOL, Vol. 61, No. 8, 08.2020, p. 1034-1041.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Weinrich, JM, Warncke, M, Wiese, N, Regier, M, Tahir, E, Heinemann, A, Sehner, S, Püschel, K, Adam, G & Laqmani, A 2020, 'Feasibility of extremely reduced-dose CT of the thoracic spine in human cadavers', ACTA RADIOL, vol. 61, no. 8, pp. 1034-1041. https://doi.org/10.1177/0284185119891417

APA

Weinrich, J. M., Warncke, M., Wiese, N., Regier, M., Tahir, E., Heinemann, A., Sehner, S., Püschel, K., Adam, G., & Laqmani, A. (2020). Feasibility of extremely reduced-dose CT of the thoracic spine in human cadavers. ACTA RADIOL, 61(8), 1034-1041. https://doi.org/10.1177/0284185119891417

Vancouver

Weinrich JM, Warncke M, Wiese N, Regier M, Tahir E, Heinemann A et al. Feasibility of extremely reduced-dose CT of the thoracic spine in human cadavers. ACTA RADIOL. 2020 Aug;61(8):1034-1041. https://doi.org/10.1177/0284185119891417

Bibtex

@article{0fc30d3627dc4dc4b19f3904c649bcfb,
title = "Feasibility of extremely reduced-dose CT of the thoracic spine in human cadavers",
abstract = "BACKGROUND: According to the as low as reasonably achievable (ALARA) principle, radiation exposure in computed tomography (CT) should be minimized while maintaining adequate image quality. Dedicated CT protocols combined with iterative reconstruction (IR) can reduce radiation dose and/or improve image quality.PURPOSE: To investigate the feasibility of extremely reduced-dose (RD) CT of the thoracic spine in human cadavers using a standard-dose (SD) and three different RDCT protocols reconstructed with filtered back projection (FBP) and IR.MATERIAL AND METHODS: The thoracic spines of 11 cadavers were examined using different RDCT protocols with decreasing reference tube currents (RDCT-1: 50 mAs; RDCT-2: 30 mAs; RDCT-3: 10 mAs) at 140 kV. A clinical SDCT (70 mAs, 140 kV) served as reference. Raw data were reconstructed using FBP and two increasing levels of IR (IRL4 and IRL6). Images were evaluated for image quality, diagnostic acceptability, and visibility of anatomical structures according to a 5-point-scale.RESULTS: Regardless of the reconstruction technique, image quality was rated as diagnostically acceptable for all cadavers in SDCT and RDCT-1. Image quality of reconstructions with FBP were generally rated lower. Application of IR improved image quality ratings in SDCT and RDCT. RDCT-2 with IR was the most reduced-dose CT protocol which enabled diagnostically acceptable image quality in all cadavers. Compared to SDCT, RDCT protocols resulted in significantly reduced effective radiation doses (SDCT: 4.1 ± 1.5 mSv; RDCT-1: 2.9 ± 1.1 mSv; 2:1.7 ± 0.6 mSv; 3:0.6 ± 0.1 mSv; P = 0.001).CONCLUSION: Diagnostically acceptable RDCT of the thoracic spine with 1.7 mSv is feasible using IR.",
author = "Weinrich, {Julius Matthias} and Malte Warncke and Nis Wiese and Marc Regier and Enver Tahir and Axel Heinemann and Susanne Sehner and Klaus P{\"u}schel and Gerhard Adam and Azien Laqmani",
year = "2020",
month = aug,
doi = "10.1177/0284185119891417",
language = "English",
volume = "61",
pages = "1034--1041",
journal = "ACTA RADIOL",
issn = "0284-1851",
publisher = "SAGE Publications",
number = "8",

}

RIS

TY - JOUR

T1 - Feasibility of extremely reduced-dose CT of the thoracic spine in human cadavers

AU - Weinrich, Julius Matthias

AU - Warncke, Malte

AU - Wiese, Nis

AU - Regier, Marc

AU - Tahir, Enver

AU - Heinemann, Axel

AU - Sehner, Susanne

AU - Püschel, Klaus

AU - Adam, Gerhard

AU - Laqmani, Azien

PY - 2020/8

Y1 - 2020/8

N2 - BACKGROUND: According to the as low as reasonably achievable (ALARA) principle, radiation exposure in computed tomography (CT) should be minimized while maintaining adequate image quality. Dedicated CT protocols combined with iterative reconstruction (IR) can reduce radiation dose and/or improve image quality.PURPOSE: To investigate the feasibility of extremely reduced-dose (RD) CT of the thoracic spine in human cadavers using a standard-dose (SD) and three different RDCT protocols reconstructed with filtered back projection (FBP) and IR.MATERIAL AND METHODS: The thoracic spines of 11 cadavers were examined using different RDCT protocols with decreasing reference tube currents (RDCT-1: 50 mAs; RDCT-2: 30 mAs; RDCT-3: 10 mAs) at 140 kV. A clinical SDCT (70 mAs, 140 kV) served as reference. Raw data were reconstructed using FBP and two increasing levels of IR (IRL4 and IRL6). Images were evaluated for image quality, diagnostic acceptability, and visibility of anatomical structures according to a 5-point-scale.RESULTS: Regardless of the reconstruction technique, image quality was rated as diagnostically acceptable for all cadavers in SDCT and RDCT-1. Image quality of reconstructions with FBP were generally rated lower. Application of IR improved image quality ratings in SDCT and RDCT. RDCT-2 with IR was the most reduced-dose CT protocol which enabled diagnostically acceptable image quality in all cadavers. Compared to SDCT, RDCT protocols resulted in significantly reduced effective radiation doses (SDCT: 4.1 ± 1.5 mSv; RDCT-1: 2.9 ± 1.1 mSv; 2:1.7 ± 0.6 mSv; 3:0.6 ± 0.1 mSv; P = 0.001).CONCLUSION: Diagnostically acceptable RDCT of the thoracic spine with 1.7 mSv is feasible using IR.

AB - BACKGROUND: According to the as low as reasonably achievable (ALARA) principle, radiation exposure in computed tomography (CT) should be minimized while maintaining adequate image quality. Dedicated CT protocols combined with iterative reconstruction (IR) can reduce radiation dose and/or improve image quality.PURPOSE: To investigate the feasibility of extremely reduced-dose (RD) CT of the thoracic spine in human cadavers using a standard-dose (SD) and three different RDCT protocols reconstructed with filtered back projection (FBP) and IR.MATERIAL AND METHODS: The thoracic spines of 11 cadavers were examined using different RDCT protocols with decreasing reference tube currents (RDCT-1: 50 mAs; RDCT-2: 30 mAs; RDCT-3: 10 mAs) at 140 kV. A clinical SDCT (70 mAs, 140 kV) served as reference. Raw data were reconstructed using FBP and two increasing levels of IR (IRL4 and IRL6). Images were evaluated for image quality, diagnostic acceptability, and visibility of anatomical structures according to a 5-point-scale.RESULTS: Regardless of the reconstruction technique, image quality was rated as diagnostically acceptable for all cadavers in SDCT and RDCT-1. Image quality of reconstructions with FBP were generally rated lower. Application of IR improved image quality ratings in SDCT and RDCT. RDCT-2 with IR was the most reduced-dose CT protocol which enabled diagnostically acceptable image quality in all cadavers. Compared to SDCT, RDCT protocols resulted in significantly reduced effective radiation doses (SDCT: 4.1 ± 1.5 mSv; RDCT-1: 2.9 ± 1.1 mSv; 2:1.7 ± 0.6 mSv; 3:0.6 ± 0.1 mSv; P = 0.001).CONCLUSION: Diagnostically acceptable RDCT of the thoracic spine with 1.7 mSv is feasible using IR.

UR - https://journals.sagepub.com/doi/abs/10.1177/0284185119891417?rfr_dat=cr_pub%3Dpubmed&url_ver=Z39.88-2003&rfr_id=ori%3Arid%3Acrossref.org&journalCode=acrc

U2 - 10.1177/0284185119891417

DO - 10.1177/0284185119891417

M3 - SCORING: Journal article

C2 - 31840526

VL - 61

SP - 1034

EP - 1041

JO - ACTA RADIOL

JF - ACTA RADIOL

SN - 0284-1851

IS - 8

ER -